Cosmetics with peptides: TOP best manufacturers and creams, serums, masks, products from the pharmacy

Cosmetics with peptides have a beneficial effect on the deep layers of the skin, delivery of nutritional components to the dermis, and improvement of biological processes occurring in cells. The substances are contained in creams, preparations for mesotherapy and biorevitalization. Cosmetics should be selected in accordance with age and problems, because peptides not only rejuvenate, but also erase hyperpigmentation and relieve inflammation.

The most well-known products with them are creams and serums from Evalar, Mizon, Secret Key, The Ordinary, Vitex-Belita. It is best to use them in courses and alternate.

How do peptides work in cosmetology?

Peptides are used in cosmetology due to the following properties of these particles:

the ability to restore blood circulation and oxygen supply to the skin;
normalization of the moisture level of the dermis;
increased production of collagen and elastin;
delivery of nutritional components of care products to the deep layers of the skin;
counteracting the aging process;
neutralization of the effects of toxins on the dermis;
restoration of the process of skin cell division characteristic of youth.

Synthetic peptides found in creams are particles of alpha amino acids that have the ability to penetrate deep enough into tissues. They are used as transport to deliver nutritional components missing to the skin.

Types of peptides

Cosmetologists distinguish 7 main groups of peptides used in creams from pharmacies or professional ones:

Stimulants – like palmitoyl tetrapeptide-3. This substance is part of immunoglobulin G in combination with hexadecanoic acid. Stimulants have a strong anti-inflammatory and protective effect, activate the restoration of innate tissues and capillary intima. In addition, stimulants inhibit the activity of elastase and collagenase, enzymes that destroy collagen and elastin. Face cream with peptides of this group is used to quickly restore the skin, remove swelling and heal wounds.
Stabilizers act as antioxidants, normalize the production of collagen and elastin, restore and maintain water balance. These include, for example, palmitoyl tripeptide-5, matrixyl TM. A cream with such substances is recognized as the best anti-aging face cream, because... promotes skin rejuvenation even at a very mature age.

Blockers – argireline, acetyl ocapeptide-3 (better known under the commercial name “New snap-8”). Their role is to suppress nerve impulses that cause contraction of facial muscles. They act in different ways: they inhibit the corresponding neurotransmitter, reproduce the effect of a neuromuscular antidote, etc. In any case, such a cream reduces involuntary muscle tension, which, in turn, allows you to get rid of many facial wrinkles.
Regulators – melanostatin-5TM. These kinds of substances suppress the production of melanin, which leads to noticeable lightening of the skin. This is one of the most powerful bleaches.
Immunomodulators - like the already mentioned palmitoyl tetrapeptide-3. A cream with immunomodulators increases the skin's resistance to inflammation and irritants, as well as pathogenic microflora.
Neurotransmitters – developed for the most sensitive skin. For example, rigin is a substance that inhibits the activity of interleukins, inflammatory mediators. This remedy reduces allergic reactions to external factors. Well, the absence of inflammation and irritation quickly puts delicate skin in order.
Improving microcirculation - palmitoyl tripeptide-5, for example. It stimulates the regeneration of not only the skin, but also connective tissue and vascular walls. And with improved microcirculation, swelling automatically decreases and dark spots disappear.

Peptide creams can be used at any age. However, the indication for their use is, of course, age-related changes. For young beauties, the cream will be useful only if the skin is highly sensitive and prone to allergies.

The benefits and harms of peptides

Peptides for aging skin are beneficial, but in some cases they are also harmful. The benefits of exposure to these substances are as follows:

the process of cell division accelerates, that is, the skin rejuvenates;
it receives more nutrients, which also promotes regeneration and increased elasticity;
the protective properties of the epidermis are enhanced, it reacts less to negative influences from the inside and outside;
a noticeable cosmetic effect appears, that is, increased skin elasticity, disappearance of acne, irritation and greasy shine, improved color, disappearance of bruises around the eyes, fine wrinkles, swelling and spots.

It is difficult to harm cosmetics with peptides, but a negative reaction can still occur:

If a woman is allergic to any of these substances. They are used with auxiliary components; they themselves are artificially created.
If you have diseases: diabetes, tumors, infections, dermatological problems, rheumatoid arthritis. Peptides, due to their active action, can provoke an exacerbation.

Some women complain about the lack of effect from cosmetics. But this may mean that it is too early for them to use such products, since the skin itself copes with recovery.

We recommend reading about the benefits of using peptides in injections for facial skin. From the article you will learn about the mechanism of action of peptides, use for mesotherapy, before and after results, the best drugs. And here is more information about how to choose a cream for mature skin.

Peptide cosmetics, reviews from cosmetologists

Cosmetologists often use peptide cosmetics in their procedures and note its positive properties and visible effect. However, there are also those who are afraid of the short term use of peptides and their possibility of interfering with the activity of skin cells and the body. Because due to the short period of use of the product in cosmetology, the possibility of its negative effects may not have been well studied.

Thus, science does not stand still, and its innovation, such as peptides, is already competing with many cosmetic substances and procedures. Therefore, today they can be called the future of cosmetology.

What do peptides contain?

Peptides can be contained in external products (creams, masks, serums for the face, eyelids), injectable preparations and capsules, powders for oral administration. The first ones are used in normal daily care, but it takes several weeks to get the effect.

Preparations for injection are used during mesotherapy or biorevitalization. They provide the expected result faster and more pronounced. But the procedures are accompanied by side effects: redness of the skin, papules.

Peptide complex - what is it?

A peptide complex is a set of particles of different alpha amino acids, the action of which not only does not contradict each other, but also gives a more noticeable effect than when using each component separately. Each of them differs in composition and type of effect on the skin.

For example, clotorphine stimulates collagen production, which provides a lifting effect. Argireline works to relieve muscle spasm, that is, smoothes out wrinkles. Rigin relieves inflammation, melanostatin-5TM eliminates hyperpigmentation.

Several peptides are almost always used in cosmetic products. But the packaging must bear the designation “peptide complex” or IPH.

Consumer Reviews

Reviews from women who have tried products containing peptides are very positive. Many people note a significant visible lifting effect after several weeks of using the face cream. They also talk about the cumulative effect of body creams that help fight skin imperfections and orange peel, since the effect does not appear immediately, but after a long time. Peptide cosmetics "Lora" also receives positive reviews. The effect is noted after the first procedure. The pleasant smell and light consistency of the creams in this line are often mentioned.

Cosmetics with peptides by manufacturer

Cosmetics with various types of peptides and complexes of these substances are produced in South Korea, Belarus, Russia, the USA, Switzerland, and France. The most affordable products are from manufacturers from the first three countries.

Russian-made cream

The most famous peptide creams and serums produced in Russia:

"New Line" from "Kora"

This is a whole line of cosmetics, it contains compositions for day and night care of the face, eyelids, etc.

The creams contain palmitoyl tripeptide-38 complex, as well as vegetable oils, glycerin, cocoa, and soy extract. They are suitable for dry skin, nourish and moisturize it.

Products from "Repharm"

The company produces not only a cream with peptides for the skin around the eyes and face, but also lip balms, a body massage composition, and an anti-cellulite product.

Repharm has cosmetics for older ladies and anti-acne cosmetics for young consumers.

Remedies from "Evalar"

These are mainly creams for the face, eyelids, and hands with peptide components. Evalar has products for oral use that help improve well-being and skin condition.

Belarusian cosmetics

Belarusian peptide cosmetics are represented by the following brands:

"Vitex-Belita", which has a series of "Peptide Youth Vaccine";
“Masstige”, which has among its products an eye gel with rice and soy peptides “Volcanic Ash”.
“DNC”, with “Peptides-Botox-Effect”, supplemented with hyaluronic acid.

The first brand on the list is the most popular. But this is not surprising, since Vitex has products for the face, skin around the eyes, hands, and body. And not only creams, but also washes, concentrates, masks. All are designed to combat aging and dry skin.

Korean cosmetics

Korean anti-aging peptide cosmetics are the following brands:

"Mizon"
"Secret Key"
"Ottie"

Each has entire lines of products with peptides to provide not just a one-time, but a complex effect. These are washing gels, toners, emulsions, day and night creams, serums, masks, including fabric masks, and eyelid patches. With them, the skin receives nourishing and moisturizing components around the clock. It is very important to use all means so that a noticeable visual effect appears.

Watch this video about how peptides work, their types and applications:

How to use it correctly

Cosmetics of this kind are not considered medicinal, and peptides, despite their effectiveness, are not biologically active substances in the full sense of the word. That is, there are no restrictions on use - in courses, at certain intervals, there are no.

The cream, of course, includes not only peptides. However, additional ingredients are rarely active. Rather, these are substances that allow the product to be used by owners of different skin types. So, for oily skin, it is worth choosing a product with the lightest possible structure, and for dry skin, an option containing oils like olive or grape.

Recommendations for using cream with peptides are extremely simple:

Peptides do not accumulate in the dermis layer, so a visible effect is possible only with regular use. As a rule, the cream is applied twice a day.
To enhance the effect of the composition, you should resort to scrubs and peels as often as possible: they free the skin from dead horny scales. The fact is that the particles ready to peel off change their arrangement, and, therefore, prevent the penetration of peptides, since they block the gaps between the scales.

Find out which scrubs are best for oily faces in this material.

You need to check the expiration date. When opened, the product produces an effect only for 2–4 months.
For better care, especially for dry skin, it is recommended to use combined cosmetics, such as peptide-placental cream.

Peptide-placental cream average cost is 350 rubles.

Peptides do not cause allergies, but other components may be allergens. A skin test is necessary.

TOP 10 creams with peptides for the face

It is best to choose a face cream with peptides from the top 10, which includes formulations from Russia, South Korea and France. It is possible to say which one is suitable in a particular case only after use.

Libriderm

Peptide Librederm is a cream from the Librederm Collagen line. It includes tools for:

faces at night and morning;
hands;
century;
neck and décolleté areas (can also be used for the face).

The set is complemented by an alginate mask with collagen, a serum that is applied under creams, and hygienic lipstick. The products moisturize, regenerate and tighten the skin, which smooths out fine wrinkles and defines the oval of the face more clearly. Creams protect against the negative influence of the environment and prevent moisture from evaporating from the surface.

Meiyanqiong

The Chinese remedy Meiyanqiong contains argireline and 6 more peptides, aloe vera, and therefore acts as follows:

increases the level of moisture in the epidermis;
helps relax tense facial muscles;
smoothes out small wrinkles.

The first effect will appear after a week of daily use. The cream-serum has a high concentration of active substances, so it is advisable to buy it no earlier than 30 years. Meiyanqiong is indicated for any skin type; it can be applied to the eyelids, neck and below.

Mizon

Mizon Peptide Ampoule Cream contains a large volume of 3-peptide nanocomplex and hyaluronic acid. Therefore, it is perfectly absorbed and acts quite quickly:

stimulates collagen production;
maintains an optimal level of moisture in the dermis;
improves blood circulation, making the complexion fresher.

You can enhance the result of application by using Mizon Peptid 500 serum cream. It is applied to clean skin first. Serum can be added to foundation and masks.

Refarm for eyelids

Repharm is a peptide eyelid product that is best used during the day under makeup. In addition to useful components, sodium alginate, chamomile extracts, green tea, hyaluronic acid, it also contains silicones - cyclomethicone and dimethicone. The product evens out the skin of the eyelids and protects it from drying out and thinning. But this effect is present while the cream is on its surface; after washing it off, it disappears.

Evalar

The Evalar concern has an anti-aging product called Qi-Clim Botoeffect. The composition contains argireline, phytoestrogens and hyaluronic acid, so the cream is suitable for women over 30. The manufacturer promises an increase in skin elasticity and the disappearance of mild facial wrinkles. The effect will be noticeable after 10 days of use at night (the product has a dense consistency).

Anti-aging face cream "Lora"

Anti-aging peptide face cream “Lora” also contains hyaluronic acid, panthenol, vitamins, glycerin, and a complex of oils. And the composition does not contain parabens or sulfates, which dry out the skin. The components of the product provide a moisturizing effect, stimulate the division of collagen cells, increase elasticity, and even out the complexion. The cream is needed from the age of 30. You can apply it day and night; such regularity will give the best results.

Revilain peptide cosmetics: night anti-aging cream, anti-wrinkle

Revilain is a peptide cosmetics for the face, eyelids and body, but the most famous product is a night cream, which contains:

peptide complex A-6;
concentrated extracts of chamomile, St. John's wort, calendula, sage;
hydrolyzed collagen;
glycerol;
olive and castor oils;
betaine;
titanium dioxide.

Its use cleanses the skin of toxins, improves blood circulation, moisturizes, smoothes, and restores complexion. The cream visually rejuvenates and prevents the appearance of new age-related changes in cells. It can be used for the neck.

Vichy

The peptide remedy from Vichy is called “LIFTACTIV Nuit”. It is intended for

evening care for women over 30 years old. Contains:

a unique patented component of rhamnose, which stimulates collagen production and increases elasticity;
apricot oil, karite;
vitamins.

All this allows you to detect the lifting effect after 4 days of use. The skin also brightens and pigment spots disappear.

Syn-ake Lifting Cream Set with snake peptide

Snake peptide, which has a beneficial effect on aging skin, is found in the “Syn-ake Lifting Cream Set” from Secret Key. The main component is synthesized artificially. But its properties are similar to the effect that occurs when applied externally from the venom of the temple viper:

relaxation of superficial facial muscles;
erasing fine wrinkles;
stimulation of regeneration processes in the epidermis;
increased blood circulation;
improvement of complexion;
protected from irritation.

The cream is used twice a day, applied to skin cleansed of decorative cosmetics.

"Argireline Solution" - a unique cream with argireline

Among creams and serums with argireline, the most popular today is “Argireline Solution” 10% from The Ordinary brand, created for local use. The composition is applied 2 times a day to problem areas - the most noticeable facial wrinkles. It works especially well on the forehead and eyelids. After half a minute, the product is absorbed, and then you can smear the cream on top of the skin.

Folds and creases from the Argireline Solution do not disappear, but become less pronounced, and the face looks much younger. The use should be supplemented with products containing retinol; this combination will make the effect more noticeable.

Reviline cosmetics

Reviline peptide cosmetics are presented by such a manufacturer as NPTsRIZ. This institute is engaged in the production of products containing peptides. Scientist V.Kh. Khavinson has been studying their nature and the results of their impact on the body for many years. Therefore, the peptides included in the products produced by the institute bear his name. The institute’s products cannot be found in a regular pharmacy; they are sold only by partners of the Scientific and Research Center for Reproductive Medicine and Health. The Reviline cream line consists of fifteen products. Peptide cosmetics NPTsRIZ includes the following care products:

Micellar cleansing toner;
Tonic ph balance;
Anti-spider veins cream;
Intensive eye creams, anti-swelling;
Day, night, anti-wrinkle face cream;
Face cream for problematic skin prone to acne and comedones;
Foot cream for corns and calluses;
Cream for varicose veins;
Nourishing hand cream;
Anti-cellulite body cream;
Body cream for stretch marks and scars.

Among the presented options of creams, anyone will be able to choose the one that suits them, and the result will not be long in coming.

Eye cream with peptides: which one is better to use?

When choosing an eye cream with peptides, you should pay attention to the best products, according to girls who have tried them on themselves:

"Mad Hippie Skin Care Products"	The cream contains matrixyl, haloxyl, niacinamide and vitamin K. The rich composition helps not only get rid of dryness, erase wrinkles and provide lifting, but also lighten dark circles under the eyes.
“Firming DMAE Eye Lift with Liftessence Peptides and Goji” by Derma E	It contains matrixyl, argireline, hyaluronic acid, DMAE, caffeine. The complex of substances stimulates collagenosis, moisturizes, and restores the protective barrier of thin eyelid skin without weighing it down.
"MyChelle Dermaceuticals"	The eye cream contains matrixyl, oligopeptides, squalane, rose moschetta oil, olive oil, jojoba oil, mango oil, hyaluronic acid, marine collagen, so it is quite expensive. But the price is justified; the result of use is noticeable rejuvenation of the eyelids and skin tightening.
Kiehl's	Contains the haloxyl peptide complex, vitamin C. There are a large number of useful components in the cream, so it copes well with a network of wrinkles, swelling and darkness under the eyes.

Firming and lifting day cream, ELIZABETH ARDEN

Cost - from 4,320 rubles

Where to buy: goldapple.ru

Acetyl octapeptide consists of eight amino acids and acts similar to argireline or Botox. It reduces the conductivity of neurosignals in the facial muscles, relaxes facial muscles and thus reduces the severity of facial wrinkles and slows down their formation.

The cream helps restore the epidermal barrier of the skin and significantly improves its condition. Moisturizes and nourishes, gives a youthful glow, improves firmness and elasticity, protects from ultraviolet radiation.

Professional cosmetics with peptides for the face

Professional cosmetics containing peptides intended for the face include preparations for injection during mesotherapy and products for use at home. The latter are used externally, and these are not only creams, but also serums, concentrates, masks, which contain a high percentage of active ingredients.

"Skinlite" serum

Skinlite is a peptide serum with argireline produced in Korea. Besides

The main component in it also contains copper tripeptides, plant extracts, and snail mucus. The effect on the skin is quite active, and so that it does not forget how to repair itself, “Skinlite” is used as follows:

course of 30 days (morning and evening);
pause of 2 weeks;
another 30 days of use.

The product is applied to the skin under a caring cream. It also enhances its effect. After 2 courses, wrinkles will become less noticeable, especially those on the forehead and around the eyes.

Peptide mask

An excellent example of a professional peptide mask is “NUTRI-PEPTIDE Hydra Vitality Mask” from GIGI. The product is used twice a week, applied to the face for 5 minutes, then washed off. Then you need to use the cream.

In addition to peptides, the product contains algae, glycerin, palmitic and glyceric acids, and polysaccharides. Therefore, the mask can be used for any skin type. The result will be an increase in the level of moisture in it, elasticity, and smoothing out of small age-related folds. The manufacturer recommends the mask for ages 40 and older.

Hyaluronic acid with peptides for the face

Products containing peptides and at the same time hyaluronic acid:

Cream "RESIST INTENSIVE REPAIR" from Paula's Choice. The composition contains palmitol tetrapeptide, hyaluronic acid, as well as green tea extract, vitamins A, E, jojoba oil, retinol, niacinamide. The product was created for evening care of dry, aging skin.
Redermic C cream from La Rosh Posay. Created to smooth out wrinkles, hydrate and nourish combination or normal skin. The composition contains neurosenin and hyaluronic acid supplemented with vitamins.
"Renergie Multi-Lift" from Lancome. Oligopeptides and hyaluronic acid are supplemented with plant components and adenosine. Thanks to them, the skin rejuvenates by increasing the production of protein chains in it. The product is used at night.

Anti-aging peptides

The list of anti-aging peptides used in professional cosmetics is constantly growing, but now in most formulations it is not difficult to find:

Argireline . This is a muscle relaxant substance that exists to relax muscles, erase wrinkles and prevent the formation of new folds. Argireline is a weaker alternative to Botox, used only for injections. It is the basis of Exclusive Jour creams from Lierac, Youth Restore Day Cream from Jeffrey James Botanicals, Predermine serum from Darphin, and Defi Lift 3D Eye Counter Lift eyelid emulsion from Gatineau.
Matrixyl . It consists of 5 amino acids and a fatty acid, penetrates deeply, stimulates the production of collagen and elastin, that is, it tightens the skin and evens it out. Matrixyl is contained in Anti-wrinkle facial cream from Dr.Sea, Aguamax Rich Firming Gel Cream from Limoni, Nasolabial Fold+ Multi-Peptide Cream from Reviva Labs, Age Control Rebuilding gel from Holy Land.
Acetyl octapeptide . Reduces the depth of wrinkles, as it consists of 8 amino acids and works like argireline. It is found in Elizabeth Arden Ceramide Lift and Firm Day Cream for the face and Asdm Beverly Hills Age Reversing Eye Cream for the eyelids.
Hexapeptides 9 and 11 . Substances enhance collagen synthesis, brighten, and improve skin texture. The first is in the “Firming Night Cream” from Dr.Sea, “Skin-Structure Serum” from Filorga, the second is in the “Ultrasmoothing Eye serum” from Dermalogica, “Quercetin & Oak Antiaging Antiwrinkle & Firming Face Serum” from Korres.

In addition to the listed substances, anti-aging formulations use glutathione, acetyl tetrapeptide-9, dipeptide-2, copper tripeptide and many other similar components.

Copper peptides for face

Copper peptides are used in facial products:

“Black Snail, All In One Cream”, “All In One Snail Repair Cream” from Mizon;
"Aguamax Rich Firming Gel Cream" from Limoni;
"CAD Cell Cream" from Lioele.

These substances consist of 3 amino acids and help reduce the depth of wrinkles and prevent the appearance of new ones. Copper peptides stimulate the strengthening of the collagen framework of the skin and regenerate it. They are also used in hair products, as the substances activate growth. Another important quality of copper peptides is the ability to transport other substances beneficial to the dermis to the lower layers.

Watch this video about 10 active products with peptides with anti-aging and botox effects:

Top brands

The best brands producing cosmetics with peptides:

Reviline pro is based on the production of premium creams. The products contain synthetic peptides, as well as natural herbal ingredients, which attracts a number of buyers.
Revilab is a brand that produces cosmetics aimed at skin rejuvenation. The line contains not only peptides, but also hyaluronic acid. All products are certified.
Mizon is a Korean brand that produces innovative cosmetics for men and women. All products undergo a series of tests, so they are absolutely safe.
La Miso - this brand produces skin, hair and oral care products. The main laboratory is located in Korea and 2 more research centers in Germany and Japan. The products are of high quality.
Coxir is a Korean brand of caring cosmetics. Each line contains a maximum of herbal ingredients, which is why most buyers prefer this brand.

Peptides for skin: oligopeptides, biomimetic

Among the peptides used for skin rejuvenation, the following deserve special attention:

Oligopeptides , considered by cosmetics specialists to be an “elixir for old age.” They contain up to 20 amino acids, so the substances increase the level of moisture in the thickness of the skin and accelerate the process of formation of new cells of the collagen layer. This makes it more elastic and fine wrinkles disappear.

The most famous component of this group is palmitol oligopeptide. Based on it, “Sleep and Peel Resurfacing night cream” from Filorga (for the face), “Idealist” from Estee Lauder (for eyelids), “Predermine” from Darphin (serum), “Lisse Minute” from Clarins (con from Planeta Organica) were created , collagen cream from Librederm.

Biomimetic peptides , which first appeared in South Korean cosmetology, there are more than 70 in total. These substances are introduced mainly into preparations for mesotherapy and biorevitalization, for example, DERMAHEAL, REVOFIL, AQUASHINE. Biomimetic peptides stimulate an increase in moisture levels, the growth of collagen and elastin cells, suppress the formation of components that reduce the volume of hyaluronic acid, and brighten the skin.

Methods for Improving Peptide Penetration

Physical methods.
Chemical methods.

Among the physical methods there are:

Iontophoresis. It is the introduction of active cream molecules using electric current.
Ultrasound (sonophoresis). It is the effect of an ultrasonic wave, under the influence of which the cells of the stratum corneum move, and the active components penetrate better into the skin.

Chemical methods involve adding an active component to the peptides - a lipophilic derivative of amino acids. This increases the ability of nutrients to penetrate the skin.

Peptides or hyaluronic acid - which is better?

Which is better, peptides or hyaluronic acid, needs to be decided depending on the problems and age. Dehydration is a common cause of premature skin aging for young women, and in this case, formulations with “hyaluronic acid” are sufficient. Peptides up to 30 years may be needed for inflammation, uneven complexion, and pigmentation.

And at a more mature age it is better to use cosmetics with them. If hyaluronic acid only increases the level of moisture in the dermis, then peptides affect the biological processes in it. Thanks to the active substances, young cells are formed faster and in greater volume. This gives rejuvenation.

Rating of facial serums

In the top of the best products, we included concentrates that have earned the most positive customer reviews from the lines of budget and premium brands. Despite the fact that this list also includes inexpensive domestic cosmetics, the cost of the products will not be low. As a rule, their price is 2-2.5 times higher than creams of a similar brand.