Emla. Instructions for use, composition, how to apply before epilation of the bikini area. Analogues of the product

Production form

White, soft cream of uniform consistency produced in Switzerland "Emla" is available in 3 versions:

• a patch with a 5% cream emulsion applied on a soft base;
• tubes 5 pcs. 5 g each + 12 stickers, which allow you to fix the Emla bandage on the skin for 4-5 hours;
• tube 30 g + 12 stickers for fixation.

It is more convenient to buy sealed tubes of pain-freezing cream, 5 g each. This is hygienic and economical, because one tube is enough to treat 50 cm2 of the body.

In 2 weeks

Proper nutrition - a diet based on dairy and plant products - will help reduce discomfort during hair removal. Give up coffee, chocolate, sweets, fast carbohydrates ().

Include the following foods in your diet:

• cottage cheese, cheese, eggs, fermented baked milk and other fermented milk products;
• fresh fruits and vegetables;
• legumes, greens, nuts.

If possible, avoid using bronzing gels, lotions, creams, self-tanners, drugs based on fluoroquinolones, sulfonamides, and tetracycline groups.

pharmachologic effect

The main ingredients are prilocaine and lidocaine - local anesthetics from the group of substituted amides. Anesthesia of the skin is provided after the medicine enters its upper layers, because the cream is not absorbed deeply into the bloodstream. When the brain stops receiving pain impulses, it is time for cosmetic or hygiene procedures.

Sensitive skin may react to the cream. Visually this is manifested by redness or pallor in the affected area. Redness is more common in patients with atopic dermatitis, and means accelerated absorption of the drug through the skin. The duration of the skin reaction with accelerated absorption is from 30 to 60 minutes.

Clinical studies have shown that in 90% of subjects, a glued patch with Emla cream applied for an hour allows for a painless injection of 2 mm under the skin, and an application of 120 minutes. provides comfortable penetration of the syringe needle by 3-4 mm.

Consumer Reviews

I decided to get laser hair removal this spring. I asked my girlfriends who did it whether it hurt or not. It's different for everyone. Some people are in pain, others are completely tolerable. In general, it all depends on the pain threshold. As far as I know, my pain threshold is average. I can bear it. This is what happened when I had epilation on my legs, everything was quite tolerable. I know that the skin in the bikini area is quite sensitive, and I immediately decided that when I did hair removal in the bikini area, I would definitely take pain relief. Pain relief with Emla cream. Everything is fine, but why is it so expensive? In my opinion, the price is absolutely unjustified. And based on the effect, I will say that the cream works and relieves pain quite well. At least I felt almost no pain.

Inna

https://www.medcentre.com.ua/medicamenty/emla-krem.html

Unfortunately, in my case, hair removal with Emla is still painful for me. Yes, there is numbness of the skin and the sensations have decreased by 5-10%, which is why I give the cream 2, not 1 out of 5. But otherwise, for me it was a waste of money, and with hot hair removal it’s just torture with a hot iron. It's a pity!

Merag

https://irecommend.ru/content/obezbolivayushchee-pri-epilyatsii-sovety-i-oshibki-mechta-stala-yavyu-kak-ne-tak-pobochka-ch

First, I spread Emla cream on one half of the bikini area and put a film on top so that it fits tightly to the smeared area. After an hour of waiting, I removed the film, wiped off the remaining cream and began the execution. For about five minutes I still gathered my courage, because my first experience of hair removal was very clearly remembered in my memory. Gathering my thoughts, I pulled back a piece of pasta and... I didn’t feel ANYTHING, absolutely nothing! She looked down: no hair, no pain, how could this be?

LetoNo4i

https://irecommend.ru/content/blagodarya-kremu-emla-teper-mozhno-delat-epilyatsiyu-sovershenno-bezboleznenno-sposob-primen

My first impressions of Emla were negative. I go to a cosmetologist for laser treatments, she always applied Emla to me in a thick layer under a film for 30 minutes, but the effect was only a couple of times out of dozens. Recently, prices at the salon went up, and she advised me to apply it myself in advance, which completely changed the effectiveness in a positive way. I also apply it under film before leaving the house. It turns out that I wait 2 hours before the procedure. Sometimes the treated area even turned red, and when it started to go numb, I always felt a slight burning sensation. By the time of the procedure, the surface of the skin is always completely numb. With this approach, the difference is very big. Even when the cosmetologist said that she was trying an even stronger and more painful regimen, the difference was not felt.

nataliaelisabeth

Read also:  Boro plus cream: detailed instructions for use, what it is used for, composition, review of analogues and reviews

https://irecommend.ru/content/podruzhilas-s-nei-ne-srazu-0

Emla cream effectively anesthetizes the skin before depilation. The product has a small number of contraindications. To achieve the expected result, you should follow the recommendations for proper application and exposure of the drug.

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Pharmacokinetics

How quickly Emla works depends not only on the amount of cream applied, but also on the thickness of the skin on different parts of the body.

For example:

• the thinnest are the genitals, the inside of the wrists, the eyelids;
• medium thickness – arms and legs, abdominal and back areas, buttocks;
• thickened – feet and palms.

Previously shaved skin loses sensitivity faster, since shaving exfoliates dead particles of the epithelium and does not prevent the cream from penetrating deeper.

Areas of use

1. Intact skin areas. After spreading 60 g of Emla onto 400 cm2 of body surface in the first 3 hours, the level of absorption was 5% for prilocaine and 3% for lidocaine. Such data demonstrate a slow absorption process. At the same dosage, the highest blood concentration of lidocaine was 0.12 μg/ml and prilocaine 0.07 μg/ml, and was achieved 4 hours after contact with the body.

2. The absorption of the drug depends on the nature of the ulcerative wounds on the legs. On extensive wounds it occurs 2 times better than on healed areas of the legs. After applying 5-10 g of Emla cream to ulcerative wounds of the legs, the peak content of lidocaine (0.05-0.85 mcg/ml) and prilocaine (0.02-0.07 mcg/ml) in plasma is reached within 2 hours. With systematic treatment of Emla wounds, the accumulation of breakdown products lidocaine and prilocaine were not observed in clinical trials.
3. Impact on the mucous membranes of the genital organs. The peak increase in lidocaine (0.18 mcg/mg) and prilocaine (0.15 mcg/ml) in plasma occurs half an hour after spreading 10 g of cream on the vaginal mucosa. The female genital organs are delicate, so you should not overexpose the drug for more than 1 hour.

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In 3 weeks

For 3 weeks, avoid mechanical traumatic effects on the skin, including depilation methods ():

• waxing
  – hair removal using a wax mixture;
• sugaring
  - hair removal using thick sugar paste;
• threading
  - hair removal using a thin thread.

From the third week, do not pluck your hair - tweezers remove part of the bulb, as a result of which the laser is not able to remove it completely. Shaving is permitted as long as the follicle is not damaged by the razor.

Indications

The pain reliever is used by patients of different age groups: from birth to old age. Rules of use for children and adults vary in the volume of product applied and the duration of application.

Indications for adults

Emla (instructions for use are included with each package) is used for pain relief:

• before injections and injections: intravenous, intramuscular and subcutaneous;
• before laser exposure during hair removal;

• before surgical removal of benign skin tumors: hemangiomas, papillomas, moles, lipomas;
• before inserting a venous blood sampling catheter;
• during surgical operations on the superficial mucous membranes of the genital organs;
• before the introduction of strong anesthesia;
• for trophic ulcerative wounds before the procedure of cleaning suppuration, fibrin and dead fibers.

Application for children

Emla cream is approved for children from birth if you need to freeze the skin before injections, take blood for analysis or administer more serious anesthetics. Instructions for use: 1 g per 10 cm2 is spread on the desired area of ​​skin and covered with cellophane.

Age group difference:

If a child is diagnosed with atopic dermatitis, the duration of action of the anesthetic is reduced to 30 minutes, since absorption in such children occurs 2 times faster.

Where is topical anesthesia used?

Most often it is used for pain relief when puncturing the skin during catheter insertion, injections, blood sampling, as well as in the following areas of medicine, such as:

• dentistry (for removing teeth and tartar, to relieve the gag reflex during procedures);
• surgery (for superficial surgical interventions. For example, when harvesting a flap for skin grafting, during mechanical cleaning of trophic ulcers);
• dermatology (for removal of molluscum contagiosum);
• cosmetology (before tattooing, hair removal, mesotherapy, laser therapy);
• gynecology (for removal of condylomas);
• pediatrics (for blood sampling, vaccinations).

Contraindications

Emla, instructions for use of which are given below, has a number of contraindications:

1. Hypersensitivity or intolerance to anesthetic substances.
2. Violations of the integrity of the skin where the cream is applied (scratches or herpes).
3. Simultaneous use by children from 0 to 3 months. any other medications.
4. Prematurity (birth before 38 weeks).
5. Methemoglobinemia is an increase in oxidized hemoglobin in the blood and oxygen starvation of tissues.
6. During pregnancy, Emla is not prohibited, but research on this topic has not yet been completed. It is known that the drug does not have a negative effect on the child in the womb and does not complicate the birth process.
7. If a nursing woman uses the cream, then lidocaine and prilocaine are absorbed into milk only in medicinal volumes that are not dangerous for the child’s body.
8. Emla (the instructions for use clearly states) is used by pregnant women only with the permission of a gynecologist. He will study the characteristics of the pregnant woman’s condition and find out the existing risks for the expectant mother.

   
   Instructions for using Emla cream prohibit applying it around the eyes

9. The developers do not recommend applying the cream to the eyelids and mouth.
10. It is not recommended to get the cream into the ear, so it should not be used to freeze earaches.
11. Do not apply pressure to the anus and genitals of children.

The product must be tested by first spreading it on the bend of the elbow. Leave for 30 minutes and evaluate the result. If there is redness and prolonged swelling, it is better to avoid using the cream on other parts of the body.

What needs to be done immediately before the procedure?

Before the procedure, you must consult a specialist who will conduct an initial examination and survey to exclude contraindications. The procedure is not performed on patients with the following pathologies and conditions:

• herpes in the active stage;
• cancer diseases;
• decompensated diabetes mellitus;
• gray or red hair;
• tanned skin;
• skin damage;
• varicose veins;
• pregnancy and lactation;
• age up to 18 years.

If the examination shows that everything is fine with health and there are no restrictions, the specialist gives recommendations before laser hair removal, which are important to strictly follow and not ignore.

Side effects

Side effects when freezing pain with Emla occur with a low frequency of 1 in 1000 patients.

There are:

• skin reaction (on the treated area): most often - redness and swelling; less often – scratching and tingling after smearing; extremely rarely (mainly in children when the duration of application is exceeded) - pinpoint hemorrhages.
• systemic reactions: extremely rare - childhood methemoglobinemia, allergy with anaphylactic shock.
• in children, after a single use, an increase in methemoglobin was noted, which returned to normal after 13 hours.

There are known examples of inflammation of the cornea after the cream gets into the eye mucosa. The effect of the cream does not affect the state of consciousness, therefore it does not interfere with driving a car or other vehicles. If you notice the symptoms described in yourself, you should immediately remove the remaining cream and go to a therapist.

Advantages and disadvantages

Consumers appreciated Emla and noted its following advantages:

• effective skin pain relief before epilation/depilation;
• Possibility of use in the intimate area;
• no odor;
• good consistency of the product, which does not allow the cream to spread after application;
• easy and convenient use;
• a small list of contraindications;
• the ability to purchase tubes individually, which saves money.

However, consumers also discovered disadvantages:

• the need to wait until the components of the drug begin to act;
• the likelihood of side effects;
• high price of the drug.

Instructions for use of Emla cream

Emla (the instructions for use describe the process step by step) relieves pain according to the following scheme:

1. The contents of the Emla tube are squeezed onto the mucous membrane or onto the desired area of ​​the body. The printed tube is designed for one-time use. Leftovers should be thrown away immediately.
2. To insert a syringe needle or catheter - 1/2 of a 5 g tube is spread generously onto the site of future injection, covered with a bandage and left for a period of 1 to 2 hours.
3. Removing warts – 1.5-2 g is applied to the problem area and left for 1-3 hours.
4. Taking a skin graft in a hospital setting - 1.5-2 g of cream is applied, the area is covered with a bandage and left for 2-5 hours.
5. Anesthesia of ulcerative wounds of the lower extremities - dose for 1 time - 2-8 g, depending on the size of the lesion. It is necessary to smear a thick layer, but no more than 10 g at a time. Leave to freeze for 30 minutes. If the ulcers are prolonged, this does not allow the cream to penetrate quickly. Emla should be left for an hour. Wounds should be cleaned mechanically a maximum of 10-15 minutes after wiping off the remaining Emla.

6. Men apply 1 g of Emla per 10 cm2 to the genitals and leave for 15 minutes. Women apply 1-2 g to the painful area and leave it to act for a period of 30 minutes. up to 1 hour
7. If the composition gets into your eyes, you should immediately wash them with warm running water, lie down, and wait 1-1.5 hours for sensitivity to normalize.
8. If, after spreading the cream on the skin, redness and burning appear, the area is washed with warm water, and application is stopped until the redness subsides.

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Pain relief at home

The most painful methods of getting rid of hair are sugaring, waxing, gelling, depilation with an epilator or laser hair removal. These types are similar in the technique of removing vegetation; hairs are removed from the roots, but the hair follicles are not destroyed. The smooth effect lasts an average of 2 weeks. Usually, to reduce pain during hair removal, you can use some of the following methods, which are often sufficient without resorting to medications:

1. Steaming the skin. It is necessary to make a hot compress or take a hot bath 6 hours before the procedure and lie in warm water for at least 15 minutes. This is the optimal time for the pores to open as much as possible and removing vegetation is a breeze.
2. Scrubbing. Light exfoliation before the procedure will help reduce the pain threshold and also make it easier to pull out excess hair.
3. A cold compress reduces sensitivity. Apply a freezing substance to the area to be epilated, then wait until it dries completely.
4. Good skin tension during tearing. To do this, you need to press on the depilation site with your hands to get a tension effect.
5. Manual massage. Massage movements in the epilation area will help reduce pain.
6. You can dull the pain during the procedure with proper breathing; you need to remove hairs while taking a deep breath, in which case the pain will be reduced to a minimum.
7. Menstrual cycle. Depilation is best done on the second or third day after menstruation, since on these days the level of the pain threshold is reduced to a minimum, experts say. The most painful sensations occur during ovulation and a few days before the start of menstruation.

How to apply anesthetic cream before depilation of the bikini area and armpits?

Emla freezing cream is widely popular for hair removal at home.

It is applied in compliance with the following rules:

1. Before depilation, the entire bikini area is washed and dried.

2. The cap of the bottle is unscrewed. The pike on the reverse side breaks the integrity of the protective membrane.
3. A small volume of creamy mass (1 g - a 3.5 cm path on the skin) is squeezed out and spread in a greasy layer completely on the armpits or along the edge of underwear. It is important that there are no visible areas of skin left, otherwise pain from the laser will be felt in those places.
4. The occlusive sticker is opened, the soft part is separated from the sticky film.
5. The adhesive film is glued over the lubricated area. This enhances the effectiveness and speed of action of the cream.
6. After 1 hour, the application is removed and traces of the cream are removed.
7. The effect of Emla will already be felt, so you can start hair removal.
8. The procedure should be carried out as soon as possible after wiping off the remaining Emla product, since after 1 hour the effect of sensitivity will be restored.

Each person has different sensitivity to pain. The exposure time of the sticker on the skin is individual. Loss of skin sensitivity may take anywhere from 30 minutes to an hour.

Methods for pain relief of skin in the bikini area

In the intimate area, the skin is very thin and sensitive with a large number of nerve endings. How and how to relieve pain from hair removal in the bikini area is a question asked by everyone who has done sugaring, waxing or laser hair removal. To reduce pain sensitivity in the bikini area, cosmetologists use, in addition to the main anesthetics that we discussed above, the following:

Gel "AneStop"

A good numbing cream for bikini hair removal with rich frost. The anesthetic gel contains vitamin B, it moisturizes and promotes rapid healing of the skin. What distinguishes this product from its analogues is that it is applied in three stages.

1. AneStop gel is applied to the skin in an even layer.
2. I remove the first layer with a napkin, after 10 minutes the ointment has passed and apply it again.
3. After again 10 minutes, remove the second layer and spread the last one, it must be removed after 5 minutes.

Cream "Dr Numb"

Painkillers for hair removal Dr Numb. The creamy composition penetrates deep into the skin up to 5 mm. Before use, the skin must be degreased. Anesthetic cream is applied in a thin layer and covered with cling film. The effect lasts up to 3 hours. The cream is suitable for any part of the body; you should avoid getting the cream on the mucous membranes of the dermis.

They also use no less well-known brands of anesthetic creams that can numb the skin before bikini hair removal:

• “Depilflax” is an anesthetic gel for hair removal, suitable for legs and intimate areas, average price: from 750 rubles.
• Anesthetic colloidal solution “Golden Rose”, average price: from 1900 rubles per 20 ml.
• Cream “Deep Numb” - anesthetic cream for depilation, average price: 10 ml pack 600 rub.

Folk remedies

In addition to specialized products, folk remedies that are less harmful to the body are used as freezing before the upcoming hair removal procedure. But there is a significant disadvantage of folk recipes in that gels, sprays and creams are more effective and will quickly reduce discomfort. But still, to this day, representatives of the fair sex resort to traditional methods of pain relief; among the most effective, the following recipes at home stand out:

• Sea buckthorn oil. Has freezing properties. In this case, it is applied externally. First soak a cotton pad in the oil and then thoroughly rub it into the skin; after 1 hour, rinse the oil with warm water. The surface is ready for depilation. Effective pain reliever for bikini depilation.
• Hot spices - mustard powder, cinnamon and chili pepper. These seasonings are found in every home; they reduce sensitivity by causing a burning sensation at the upcoming site of exposure. They also help to expand the pores for further easy hair excision.

Attention! Not suitable for sensitive skin; irritation may occur accompanied by allergies.

• Mint leaves. For manipulation you will need several mint leaves and sterilized warm water. First, immerse each leaf in water, then apply it to the depilation site. Leave on the surface for 20 minutes.

Tablet analgesics

The fastest way to anesthetize the epidermis before the procedure is to take painkillers in the form of tablets, which can be purchased at any pharmacy. These drugs include:

• Analgin.
• Pentalgin.
• Diclofenca.
• Nurofen.
• Ketoprofen.

Tablet preparations are taken 1 tablet orally with a small amount of water 1 hour before depilation. When using medications, you must understand that using them in large quantities is not safe for the body. Before use, you should read the instructions and consult your doctor.

Overdose

Overdose and accumulation of toxic breakdown products of anesthetics from Emla in the body are unlikely if the dosage and application methods are followed.

1. Symptoms indicating an increase in toxins in the body: overexcitation of the central nervous system, and in especially severe cases, depression of the myocardium and central nervous system.
2. Increased sweating, headache, blurred vision, decreased blood pressure and arrhythmia may occur.

Due to the slow absorption of the main components of the composition after therapy, the patient is constantly monitored. After 3-4 hours the condition returns to normal.

Emla drug overdose, symptoms and treatment

If the recommended dosage regimen is followed, the development of systemic toxicity is unlikely. The probable symptoms of intoxication are the same as with the use of other local anesthetics: at the beginning, stimulation of the central nervous system, in severe cases, depression of the central nervous system and cardiac activity. Cases of clinically significant methemoglobinemia have been very rarely reported in children, as prilocaine in high doses can increase methemoglobin levels. Superficial application of 125 mg of prilocaine for 5 hours caused the development of moderate methemoglobinemia in a three-month-old child. Topical application of 8.6–17.2 mg/kg lidocaine led to the development of severe intoxication in infants. Severe neurological symptoms (convulsions, central nervous system depression) require symptomatic treatment: the use of mechanical ventilation and anticonvulsants. The antidote for methemoglobinemia is methylthionine. Due to the slow systemic absorption of the drug, the patient's condition must be monitored for several hours after the symptoms of intoxication have resolved.

Interaction

The use of Emla cream increases the risk of methemoglobin manifestations in people simultaneously taking antimicrobial agents.

1. The use of Emla freezing cream in increased doses causes an adaptive effect - a cumulative increase in the effects of all drugs. It is dangerous if the patient takes structurally similar drugs, for example, tocainide, since the cumulative effect can cause exceeding the permissible doses of the drugs.
2. Combinations with class III antiarrhythmic drugs and local anesthetics are used with caution, since clinical studies on their compatibility have not been conducted.
3. Beta blockers, cimetidine and other drugs that reduce the effectiveness of lidocaine potentially increase its concentration in the blood plasma when taken together for a long time. Short-term interactions have a cumulative effect.

4. Prilocaine with parallel administration of methemoglobin-inducing drugs such as nitrofurantoin, sulfonamide, phenobarbital and phenytoin enhances the analgesic effect on humans, which can lead to dizziness, headache and general weakness.

If you need to use Emla and other medications in parallel, you should definitely consult a therapist.

Emla's analogs

Cream analogues are used if there are restrictions on the use of the original product:

1. "Aurubin" - a budget substitute for Emla, which is sold in the form of an ointment for external use. The combination of prednisolone, lidocaine and dexpanthenol anesthetizes and has an anti-inflammatory effect. Used to prevent pain. Contraindications include fungal infection, the 1st trimester of pregnancy, a child under one year of age, allergies and ophthalmological diseases. The price is 350-370 rubles.

2. "Versatis" is a high-quality analogue in the form of a patch. The main component in the composition is lidocaine. It provides local pain relief at the site of application. Used to relieve pain, eliminate various types of myositis, and in the presence of neuralgic diseases. It is not allowed to apply the Versatis patch at an early or old age, with wounds on the skin or when taking anesthetics of a similar type. Price 1200-1350 rub.
3. "Kamistad" is a combined action anesthetic. It combines lidocaine and chamomile flower, which guarantees an antimicrobial and analgesic effect. "Kamistad" is prescribed to relieve acute toothache. Contraindications will be: impaired renal and liver function, heart failure, pregnancy and breastfeeding. Cost 220-240 rubles.
4. Lidocaine is closest in its mode of action on the body to Emla cream. It is produced in the form of a gel for local freezing. The gel should not be used if you have allergies, pregnancy, lactation, heart disease or in adolescents under adulthood. The cost at the pharmacy is 360-400 rubles.
5. "Naropin" – sold in the form of an injection solution. It is used for freezing during surgical interventions and to relieve acute pain. It is not recommended to use if the body is hypersensitive to ropivacaine, pregnant, breastfeeding, serious heart disease, or taking other anesthetics. You can buy Naropin for 1550-1600 rubles.

A general practitioner will help you choose a safe analogue as a replacement for the original drug Emla.

In a few hours

A few hours before hair removal, take a warm bath - this will help the skin steam and make the laser hair removal process easier. Replenish your water balance - the presence of water in the body will reduce redness and irritation after the session.

Take painkillers if necessary. They can be applied locally to the surface of the skin or taken orally. The most popular are anesthetic creams and lidocaine sprays (4%). Ibuprofen is suitable as tablets.

Price of cream in Moscow, St. Petersburg, regions

The cost of Emla cream depends on the country of origin, the prestige of the pharmacy chain and the volume of the tube.

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Women's reviews about the cream

Women's responses to Emla cream vary. 95% of users are satisfied with the analgesic effect, and 5% say the result is insufficient. Dermatological specialists confirm the positive effect of the drug, but remind us to strictly adhere to the dosage and timing of the application on the skin.

Emla cream ensures painless laser hair removal. There is no need to take pills. Applying the product for 1 hour allows you to depilate even the deep bikini area.

The product is suitable for sensitive skin. It is used both before peeling and for freezing before the sugaring procedure.

The cream is used for the hygienic treatment of ulcerative lesions. In this case, superficial anesthesia does not interfere with the normal wound healing process. Emla is used to remove pigmented nevi (brown spots on the body). According to reviews, it is impossible to withstand their removal without Emla anesthesia.

According to the described instructions for use, Emla, with the correct dosage and application, provides anesthesia to the desired skin area for 2-3 hours. During this time, peelings, sugaring, injections and blood draws are carried out painlessly. A trusted manufacturer and positive patient reviews allow us to have no doubt about the quality of the cream.

Article design: Mila Friedan

Epilators with different attachments

Modern technologies make the process of hair removal with an epilator as comfortable as possible. For this purpose, manufacturers have developed numerous attachments of different types that reduce pain.

• Cooling depilator. An epilator with a cooling attachment has a small container in its assembly into which water is poured and placed in the freezer for a while until ice forms. The cooling effect is that this nozzle blows cold air onto the skin. It reduces the sensitivity of pain receptors and prevents irritation.
• Massage. The depilator is equipped with a massage roller, which allows you to carry out the procedure in the bikini area without feeling pain.
• Water depilator. This device is made of specially rubberized inserts (they prevent water from penetrating into the epilator itself). They can be manipulated under water; the water softens the removal of hair follicles and the owner of such a device feels comfortable during the hair removal procedure.