Treating ARVI, influenza and other viral infections is usually more difficult than preventing them, especially in childhood. For successful prevention, take drugs with an immunomodulatory effect, for example, Viferon ointment. This is an inexpensive and quite effective drug that can be used not only by adults, but also by newborns, including premature babies.
Nosological classification (ICD-10)
- A41.9 Septicemia, unspecified
- A49.3 Mycoplasma infection, unspecified
- A59.0 Urogenital trichomoniasis
- A74.9 Chlamydial infection, unspecified
- B00.0 Herpetic eczema
- B00.1 Herpetic vesicular dermatitis
- B18 Chronic viral hepatitis
- B25.9 Cytomegalovirus disease, unspecified
- B34 Viral infection of unspecified localization
- B37.3 Candidiasis of the vulva and vagina (N77.1*)
- G03.9 Meningitis, unspecified
- J06 Acute upper respiratory tract infections of multiple and unspecified localization
- J11 Influenza, virus not identified
- J18 Pneumonia without specifying the pathogen
- N39.0 Urinary tract infection without established location
- N76 Other inflammatory diseases of the vagina and vulva
- O35.3 Fetal injury (suspected) due to maternal viral disease requiring maternal medical attention
- O35.8 Other fetal anomalies and lesions (suspected) requiring maternal medical attention
Treatment of various infections in adult patients
In adults, for ARVI, influenza and other pathologies of viral etiology, 500,000 IU is prescribed twice a day. Therapy lasts 5-10 days. If treatment needs to be continued, after completing the first course, take a break for 5 days, after which the therapy is repeated.
Pathologies caused by the herpes virus are indicated to be treated with a dosage of 1,000,000 IU twice a day. The course of treatment lasts 1.5 weeks. With frequent relapses, the course of therapy can last more than 1.5 weeks.
During pregnancy with a viral urogenital infection (including herpes), it is recommended to put a suppository of 500,000 IU twice a day for 1.5 weeks. Then twice a week, 1,000,000 IU per day (course therapy - 1.5 weeks). After a month, preventive therapy is indicated at a dose of 150,000 IU twice a day for 5 days. It is possible to repeat prophylaxis before childbirth.
For viral hepatitis, the medicine is indicated in a dose of 3,000,000 IU twice a day every day for 1.5 weeks. Afterwards, a maintenance course of 3,000,000 IU is prescribed every other day for six months to a year. The duration of therapy is determined by the doctor depending on the results of laboratory tests and the patient’s well-being.
For the drug to work correctly, you need to know where to store Viferon suppositories. The medication should be stored in a cool place so that the candle keeps its shape and does not melt. The optimal temperature is 2–8 °C.
Compound
Ointment for local and external use | 1 g |
active substance: | |
interferon human recombinant alpha-2 | 40000 IU |
excipients: tocopherol acetate - 0.02 g; anhydrous lanolin - 0.34 g; medical petroleum jelly - 0.45 g; peach oil - 0.12 g; purified water - up to 1 g |
Gel for local and external use | 1 g |
active substance: | |
interferon human recombinant alpha-2b | 36000 IU |
excipients: alpha-tocopherol acetate - 0.055 g; methionine - 0.0012 g; benzoic acid - 0.00128 mg; citric acid monohydrate - 0.001 g; sodium tetraborate decahydrate - 0.0018 mg; sodium chloride - 0.004 g; human serum albumin solution 10% - 0.02 g; distilled glycerin (glycerol) - 0.02 g; carmellose sodium - 0.02 g; ethanol 95% - 0.055 g; purified water - up to 1 g |
Suppositories for rectal use | 1 sup. |
active substance: | |
interferon human recombinant alpha-2b | 150000 IU |
500000 IU | |
1000000 IU | |
3000000 IU | |
excipients: alpha-tocopherol acetate - 0.055/0.055/0.055/0.055 g; ascorbic acid - 0.0054/0.0081/0.0081/0.0081 g; sodium ascorbate - 0.0108/0.0162/0.0162/0.0162 g; disodium edetate dihydrate - 0.0001/0.0001/0.0001/0.0001 g; polysorbate 80 - 0.0001/0.0001/0.0001/0.0001 g | |
base: cocoa butter and confectionery fat - up to 1 g |
Composition and release form
Ointment for external and local use 1 g
- recombinant human interferon alpha-2 40000 IU - tocopherol acetate 0.002 g - excipients: anhydrous lanolin;
medical Vaseline; peach oil; purified water in aluminum tubes of 12 g; 1 tube in a cardboard box. Gel for local use 1 ml
- recombinant human interferon alpha-2 36000 IU - excipients: alpha-tocopherol acetate solution - 5%; methionine alcohol solution - 2%; benzoic acid solution - 0.4%; citric acid - solution - 10%; sodium tetraborate solution - 3%; sodium chloride solution - 10%; human serum albumin solution - 10%; glycerin - distilled; sodium carboxymethylcellulose; purified water - in aluminum tubes of 10 ml; 1 tube in a cardboard pack
Suppositories for rectal use 1 sup.
- human recombinant interferon alpha-2: - 150,000 IU - 500,000 IU - 1,000,000 IU - 3,000,000 IU - excipients: ascorbic acid - 0.015 g (150,000 IU), 0.022 g (500,000 IU, 1,000,000 IU, 3,000,000 IU ); tocopherol acetate - 0.055 g; base - cocoa butter or solid fat in PVC/PVC strip packaging of 10 pcs.; in a cardboard pack 1 package.
Pharmacodynamics
Human recombinant interferon alpha-2b has pronounced immunomodulatory, antiviral, antiproliferative properties, suppresses the replication of RNA and DNA viruses.
The complex composition of the drugs (ointment, suppositories, gel) causes a number of new additional effects: in the presence of antioxidants (tocopherol acetate and/or ascorbic acid), the specific antiviral activity of human recombinant alpha-2b interferon increases, its immunomodulatory effect on T- and B-lymphocytes increases , the level of secretory immunoglobulins of class A increases, the level of immunoglobulin E normalizes, and the functioning of the endogenous interferon alpha-2b system is restored. Ascorbic acid and alpha-tocopherol acetate, being highly active antioxidants, have anti-inflammatory, membrane stabilizing, and regenerating properties. The use of the drug VIFERON® as part of complex therapy makes it possible to reduce therapeutic doses of antibacterial and hormonal drugs, as well as reduce the toxic effects of this therapy.
It has been established that when using the drug VIFERON® there are no side effects that occur with parenteral administration of interferon alfa-2b preparations, and no antibodies are formed that neutralize the antiviral activity of interferon alfa-2b.
Ointment "Viferon": composition, description
This is an antiviral drug that strengthens the immune system. The composition contains interferon protein, which belongs to the alpha-2b type. Available in different forms:
- ointment;
- candles;
- gel.
It is used for the prevention and treatment of diseases associated with viruses. Thanks to the destruction of pathogenic microorganisms, patients can use significantly less hormonal drugs and antibiotics, which makes them feel better and has a positive effect on their health.
The effect on the body is complex:
- antiviral – for the treatment of herpes, influenza, hepatitis, among others;
- restoration of the interferon synthesis system;
- antibacterial – treatment of mixed infections;
- stimulation of systems that synthesize antibodies;
- strengthening the immune system.
The drug stabilizes the membranes of body cells, promotes tissue regeneration, and has anti-inflammatory and powerful antioxidant effects. This contributes not only to cure from infectious pathologies, but to relatively rapid recovery.
The ointment or gel can only be stored in the refrigerator at a temperature in the range of 2-8°C. The place should be moderately damp and dark. Access for children is prohibited. The drug can be used within the expiration date, which is 2 years from the date of production.
Indications for the drug Viferon®
Ointment
viral (including herpetic) lesions of the skin and mucous membranes of various localizations;
treatment of influenza and acute respiratory viral infections in children over 1 year of age.
Gel
in complex therapy of ARVI, incl. influenza, frequent and prolonged acute respiratory viral infections, incl. complicated by bacterial infection;
prevention of acute respiratory viral infections, including influenza;
in complex therapy of recurrent stenotic laryngotracheobronchitis;
prevention of recurrent stenosing laryngotracheobronchitis;
in complex therapy of acute and exacerbations of chronic recurrent herpetic infections of the skin and mucous membranes, incl. urogenital form of herpetic infection;
in complex therapy of herpetic cervicitis.
Suppositories
In complex therapy:
ARVI, including influenza, incl. complicated by bacterial infection, pneumonia (bacterial, viral, chlamydial) in children and adults;
infectious and inflammatory diseases of newborns, incl. premature babies: meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, CMV infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis);
chronic viral hepatitis B, C, D in children and adults, incl. in combination with the use of plasmapheresis and hemosorption for chronic viral hepatitis of pronounced activity, complicated by cirrhosis of the liver;
infectious and inflammatory diseases of the urogenital tract (chlamydia, CMV infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults;
primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild to moderate course, incl. urogenital form in adults.
When can the medicine be used?
The drug is indicated for the treatment of respiratory infections of viral etiology. The medicine effectively relieves symptoms of influenza, respiratory syncytial, rhinovirus and other infections. It is actively used to treat COVID-19, including in children, pregnant and lactating women. The medication can be used even with the addition of bacterial flora:
- Inflammation of the membranes and tissue of the brain;
- Infection in the womb (cytomegalovirus, herpes, candidiasis, chlamydia, etc.);
- Pneumonia;
- Pathologies of the reproductive organs (trichomoniasis, ureaplasmosis, HPV and others).
Viferon can be prescribed together with antibacterial and antifungal medications, as it increases the immune defense of the entire body.
The product is effective against viral intestinal diseases, namely: rotavirus, enterovirus. When using the drug, vomiting, nausea, abdominal pain, diarrhea, and intoxication quickly go away.
The medicine is often used for herpetic rashes caused by Herpes simplex types 1 and 2. The product relieves itching and rash.
The drug can be used even in newborns and premature infants. It does not cause serious complications and is non-toxic.
Use during pregnancy and breastfeeding
Ointment: since when applied externally and locally, the systemic absorption of interferon is low and the drug has an effect only in the lesion, it is possible to use the drug VIFERON® during pregnancy and lactation.
Gel: since the systemic absorption of interferon when applied topically is low and the drug has an effect only in the lesion, it is possible to use the drug VIFERON® during pregnancy and breastfeeding. During lactation, do not use the drug on the area of the nipples and areola.
Suppositories: the drug is approved for use from the 14th week of pregnancy. There are no restrictions for use during lactation.
Ointment and gel - rules of use
Ointment or gel is often used to treat herpes on the skin and mucous membranes. A single dosage is 0.5 cm. The drug is applied to the skin or mucous membrane (nasal passages, tonsils) 3-5 times a day. The surfaces to be treated must be pre-cleaned. The duration of therapy is 5 days. External agents are indicated simultaneously with Viferon suppositories.
The gel can be used to treat inflammatory processes of the cervix. The product is applied twice a day. Before use, it is recommended to clean the cervical mucosa with a cotton swab so that there is no mucus. The course of therapy is 1-2 weeks. The gel is also used as part of the general treatment of cervicitis.
Attention! The tube should be stored in a cool place. Otherwise, the effectiveness of treatment is reduced.
For preventive purposes, external forms are recommended to be applied to the tonsils or nasal mucosa twice a day. Course therapy lasts up to 1 month.
Gel Viferon 36,000 ME
Side effects
Ointment: in most cases, VIFERON® is well tolerated. When applied to the nasal mucosa, side effects are weak and transient and disappear on their own after discontinuation of the drug.
Gel: in extremely rare cases, a local allergic reaction may occur in some highly sensitive individuals. In such cases, stop using the drug.
Suppositories: in rare cases - allergic reactions (skin rashes, itching). These phenomena are reversible and disappear 72 hours after stopping the drug.
Acute candylomas in women and treatment methods
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Genital warts appear due to the action of the human papillomavirus, which is often sexually transmitted. They are neoplasms of different sizes that appear on the mucous membrane or skin of the genital organ. Therefore, such growths are often called genital warts. In the article we will look at what genital warts are in more detail, what symptoms and types of growths exist, as well as methods of treatment and removal.
Reasons for appearance
The causative agent of the disease is the human papillomavirus (HPV), which infects the majority of the adult population. Depending on the type of pathogen, symptoms appear in different places and have their own shape and stage of development. Thus, strains No. 6 and 11 are responsible for the occurrence of genital warts. For symptoms to appear on the cervix, types No. 16, 18 and 35 must work.
The main reason for the appearance of infection in the body is direct contact with the mucous membranes of the patient. The strains of the virus discussed are not transmitted through household items. After transmission of the pathogen, the disease does not penetrate the blood and internal organs, but settles on the mucous membrane or skin.
The virus penetrates deep into the skin of women’s intimate places and there, in the intracellular space, actively begins to develop. When the colony becomes large enough, the pathogen appears on the skin. Only after this can it be transferred to other people. Most often, transmission of infection occurs through sexual contact, during anal or vaginal sex. Cases of transmission of the disease through oral contact have also been established.
Genital warts appear in women, regardless of their level of income and living conditions.
According to recent studies, half of the people on Earth who are sexually active are carriers of the virus. Moreover, often the same person can be a carrier of different strains of the pathogen. It is not always possible to independently determine the presence of the disease, since the virus may not show symptoms for a long time. When the immune system declines, the problem comes to the surface.
Symptoms and stages of development
After infection, the virus remains latent for a long time, 1-12 months. Most often, the first symptoms appear in the third month after infection. It is easy to determine what condylomas look like - most often they are small in size, have a pinkish-pale tint and grow on a thin thread or a small stalk.
Condylomas acuminata in women can be localized on the external genitalia, near the urethra or in the vaginal cavity. Often growths occur in the cervix and around the anus. If neoplasms appear near the urethra, urethritis may begin to develop. Because of this, when urinating, a disk appears, sharp pain in the lower abdomen and aching pain in the groin area. At the same time, damage to the external genitalia begins. This is one of the key signs of the presence of vaginal condylomas.
Sometimes neoplasms located in the cervix area connect with each other and form conglomerates of a yellowish or pastel shade. As a result, such growths can block the entire entrance to the uterus. Therefore, it is not recommended to start the disease. In extreme stages, condylomatosis develops in women, it becomes large and penetrates deeply into the tissues, destroying them.
Symptoms do not always appear, and a woman may feel something is wrong already when the condylomas begin to grow. In this case, there is a feeling of itching and burning in the vagina.
Condylomas in women cause different symptoms, it all depends on the location of the genital warts. Thus, problems arise during sexual intercourse, urination or defecation. When the growths become too large, they begin to interfere with the processes described above. But with regular visits to the gynecologist, you can notice the problem in time and begin treatment for genital warts in women.
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The manifestation of condylomas caused by HPV manifests itself differently, depending on the form. Thus, there are three main types of neoplasm:
- Latent. The virus is in a dormant state and does not show external manifestations. During this period, small conical formations may appear, which means that the pathogen begins to actively develop. During a routine examination by a doctor, the problem may be discovered after testing.
- Clinical. Peaked, papular or hyperkeratotic condylomas begin to appear on the mucous membrane. The first option involves the appearance of outgrowths with a short stalk; they resemble cauliflower in shape. Such neoplasms can be either single or multiple. The second option, papular growths, coincide in shape with flat round warts. The third option, hyperkeratotic condylomas, appear only on the labia and are characterized by a horny layer.
- Subclinical. At this stage, condylomas become flat, not protruding beyond the surface of the skin. You can usually detect such tumors by their color.
Types of condylomas
There is a type of condylomas called Buschke-Levenshtein. Such growths are usually large in size and appear due to the fusion of candylomatous growths. This growth rapidly increases in size, destroys tissue at the base and secretes sticky mucus. Although this growth is quite unpleasant, it rarely develops into a malignant tumor.
It is worth separately noting the shape of condylomas. It comes in two varieties:
- Pointed. At the clinical stage of virus development, such neoplasms appear. They can be located on the labia minora and majora, near the vaginal opening, around the anus. In rare cases, genital warts affect the cervix or mouth. Let's figure out what genital warts look like. Their color depends on the location and can be flesh-colored, purple, red or light pink. Pointed formations in women are often accompanied by painful sensations.
- Endophytic or flat condylomas in women are invisible to self-examination, as they often appear in the vagina and cervix. Despite its inconspicuous manifestation, this type is especially dangerous, as over time it can develop into oncology. It is important to take the necessary tests immediately after detection. In extreme stages, cervical cancer may begin to develop.
The condyloma in the photo belongs to the pointed variety:
Drug treatment
When the growths are in the initial stage of growth and are small in size, drug treatment of condylomas in women is possible. To do this, you need to visit a gynecologist, he will conduct an examination, tell you how to treat condylomas in women, discuss the most suitable method for you, and prescribe the necessary medicine. The treatment process itself can take place at home. How exactly to treat genital warts in women, what drugs to choose and how to use them is determined by a specialist. It is based on the patient's condition and prognosis of the disease.
One of the commonly used drugs is Podophyllotoxin (Condilin). It is based on an extract of plants from the genus Podophyllum, which promotes the death of genital warts. The medicine is applied twice a day using a special applicator. Treatment lasts 3 days, then a break is taken for a week. It is important to apply the medication only to the affected areas, avoiding contact with healthy ones. After the drug comes into contact with the condyloma, a painful burning sensation and redness occurs. Treatment lasts no more than weeks until the growth is completely destroyed.
Another effective drug for removing genital warts in women is Solcoderm. This product is of artificial origin. The composition contains several types of acids and other active chemicals. The finished mixture has a detrimental effect on the cells of genital warts. As in the previous case, the medication is applied strictly to the affected area of the mucous membrane or skin. But unlike Kondilin, it is used only once. If condylomas are not completely removed, re-use is possible. Most often, the specialist applies the drug himself.
If Solcoderm gets on healthy skin, it will result in a chemical burn, which will leave scars.
Removal of condylomas in intimate places
To ensure that condyloma in intimate places does not degenerate into a malignant tumor, they resort to direct removal. The procedure is carried out regardless of the location, shape and size of the growth. There are a large number of ways to remove condylomas in intimate places. After the procedure, the obtained samples are sent for a histological procedure to determine the degeneration into cancer.
Before getting rid of condylomas in intimate places, the doctor will determine the degree of damage to the mucous membrane or skin.
We list the most effective ways to remove genital warts in the intimate area:
- Cryosurgery. The affected area is treated with liquid nitrogen. No local anesthesia will be required during treatment. It is considered the most effective method and is often used in cases where drug treatment has not helped. The procedure is not recommended for women planning to have children.
- Diathermocoagulation. This method is designed to remove condylomas from the cervix. Usually one procedure is enough, but if there are too many formations, three repetitions are allowed. As in the previous case, this treatment is not suitable for expectant mothers.
- Surgical treatment. The affected area is cut out using a scalpel or special scissors. In this case, local anesthesia is given, and at the end of the procedure, a pressure bandage is applied for one week.
- Laser coagulation. Under the influence of laser beams, the tissues of the growth are burned out, after which a dry crust remains, which eventually disappears by itself. The procedure takes no more than 15 minutes and does not require anesthesia. Generally not suitable for removal of condylomas lata.
- Radio wave surgery. Using special equipment, tumors are burned out under the influence of high-frequency radio waves.
The choice of treatment method for genital warts depends entirely on the attending physician. He is able to accurately determine the safest and most effective method of removal. You should not rely on traditional medicine, since the wrong approach to solving the problem can aggravate the circumstances.
Directions for use and doses
Ointment, externally and locally. For herpes infection, apply a thin layer of ointment to the affected areas 3-4 times a day and rub in gently. Duration of treatment is 5–7 days. It is recommended to begin treatment immediately when the first signs of damage to the skin and mucous membranes appear (itching, burning, redness). When treating recurrent herpes, it is advisable to begin treatment in the prodromal period or at the very beginning of the appearance of signs of relapse.
To treat influenza and other acute respiratory viral infections, the ointment is applied in a thin layer to the mucous membrane of the nasal passages 3-4 times a day throughout the entire period of the disease.
Children from 1 year to 2 years - 2500 IU (1 pea with a diameter of 0.5 cm) 3 times a day; from 2 to 12 years - 2500 IU (1 pea with a diameter of 0.5 cm) 4 times a day; from 12 to 18 years - 5000 IU (1 pea with a diameter of 1 cm) 4 times a day. The duration of treatment is 5 days.
Gel, externally and locally.
In the complex therapy of ARVI, including influenza, long-term and frequent ARVI, incl. complicated by a bacterial infection: a strip of gel no more than 0.5 cm long is applied to the previously dried surface of the nasal mucosa and/or to the surface of the tonsils 3-5 times a day using a spatula or a cotton swab/cotton swab (see Note). The course of treatment is 5 days; if necessary, the course can be extended.
Prevention of ARVI, including influenza: during the period of rising incidence, a strip of gel no more than 0.5 cm long is applied to the previously dried surface of the nasal mucosa and/or to the surface of the tonsils 2 times a day for 2–4 weeks.
In complex therapy of recurrent stenosing laryngotracheobronchitis: a strip of gel no more than 0.5 cm long is applied to the surface of the palatine tonsils using a spatula or a cotton swab/cotton swab in the acute period of the disease 5 times a day, for 5–7 days, then 3 times a day day for the next 3 weeks.
Prevention of recurrent stenosing laryngotracheobronchitis: a strip of gel no more than 0.5 cm long is applied to the surface of the tonsils using a spatula or a cotton swab/cotton swab 2 times a day for 3-4 weeks, courses are repeated 2 times a year.
In complex therapy of acute and chronic recurrent herpetic infection (at the first signs of the disease or during the period of warning signs): a strip of gel no more than 0.5 cm long is applied using a spatula or a cotton swab/cotton swab to a previously dried affected surface 3–5 times per day. day for 5–6 days, if necessary, the duration of the course is increased until clinical manifestations disappear.
In complex therapy of herpetic cervicitis: 1 ml of gel is applied with a cotton swab to the surface of the cervix, previously cleared of mucus, 2 times a day for 7 days; if necessary, the duration of the course can be increased to 14 days.
Note. The gel is applied to the mucous membrane of the nasal cavity after cleansing the nasal passages, and to the surface of the palatine tonsils - 30 minutes after eating. When applying the gel to the tonsils, do not touch the tonsils with a cotton swab, but only with the gel; the gel flows down on its own along the surface of the tonsil. When applying the gel to the cervix, you should first remove mucus and discharge from the vaginal vaults and cervix with a cotton or gauze swab.
When applying the gel to the affected areas of the skin and mucous membranes, after 30–40 minutes a thin film is formed, onto which the drug is again applied. If desired, the film can be peeled off or washed off with water before reapplying the drug.
Suppositories, rectally.
1 suppository contains human recombinant interferon alpha-2b as an active substance in the indicated dosages (150,000 IU, 500,000 IU, 1,000,000 IU, 3,000,000 IU).
Acute respiratory viral infections, including influenza, incl. complicated by bacterial infection, pneumonia (bacterial, viral, chlamydial) in children and adults as part of complex therapy. Recommended dose for adults, including pregnant women and children over 7 years old VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. According to clinical indications, therapy can be continued.
Children under 7 years old, incl. For newborns and premature infants with a gestational age of more than 34 weeks, it is recommended to use the drug VIFERON® 150,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. According to clinical indications, therapy can be continued. The break between courses is 5 days.
Premature newborns with a gestational age of less than 34 weeks are recommended to use the drug VIFERON® 150,000 IU, 1 suppository 3 times a day after 8 hours every day for 5 days. According to clinical indications, therapy can be continued. The break between courses is 5 days.
Infectious and inflammatory diseases of newborns, incl. premature babies: meningitis (bacterial, viral), sepsis, intrauterine infection (chlamydia, herpes, CMV infection, enterovirus infection, candidiasis, including visceral, mycoplasmosis) as part of complex therapy. Recommended dose for newborns, incl. premature babies with a gestational age of more than 34 weeks VIFERON® 150,000 IU daily, 1 suppository 2 times a day after 12 hours. The course of treatment is 5 days.
Premature newborns with a gestational age of less than 34 weeks are recommended to use the drug VIFERON® 150,000 IU daily, 1 suppository 3 times a day after 8 hours. The course of treatment is 5 days.
Recommended number of courses for various infectious and inflammatory diseases: sepsis - 2-3 courses, meningitis - 1-2 courses, herpes infection - 2 courses, enterovirus infection - 1-2 courses, CMV infection - 2-3 courses, mycoplasmosis, candidiasis , including visceral - 2-3 courses. The break between courses is 5 days. According to clinical indications, therapy can be continued.
Chronic viral hepatitis B, C, D in children and adults as part of complex therapy, incl. in combination with the use of plasmapheresis and hemosorption for chronic viral hepatitis of pronounced activity, complicated by cirrhosis of the liver. The recommended dose for adults is VIFERON® 3,000,000 IU, 1 suppository 2 times a day every 12 hours every day for 10 days, then 3 times a week every other day for 6–12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.
For children under 6 months of age, 300,000–500,000 IU per day is recommended; at the age of 6 to 12 months - 500,000 IU per day.
For children aged 1 to 7 years, 3,000,000 IU per 1 m2 of body surface area per day is recommended.
For children over 7 years old, 5,000,000 IU per 1 m2 of body surface area per day is recommended.
The drug is used 2 times a day every 12 hours for the first 10 days, then 3 times a week every other day for 6–12 months. The duration of treatment is determined by clinical effectiveness and laboratory parameters.
The daily dose of the drug for each patient is calculated by multiplying the recommended dose for a given age by the body surface area calculated using the nomogram for calculating body surface area by height and weight according to Garford, Terry and Rourke. The calculation of a single dose is carried out by dividing the calculated daily dose into 2 administrations, the resulting value is rounded up to the dosage of the suppository.
In case of chronic viral hepatitis of pronounced activity and liver cirrhosis, before plasmapheresis and/or hemosorption, it is recommended to use VIFERON® 150,000 IU for children under 7 years of age, VIFERON® 500,000 IU for children over 7 years of age, 1 suppository 2 times a day every 12 hours. within 14 days.
Infectious and inflammatory diseases of the urogenital tract (chlamydia, CMV infection, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis) in adults, including pregnant women as part of complex therapy. The recommended dose for adults is VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 5–10 days. According to clinical indications, therapy can be continued.
Pregnant women from the second trimester of pregnancy (starting from 14 weeks of gestation) are recommended VIFERON® 500,000 IU, 1 suppository 2 times a day every 12 hours for 10 days, then 3 times for 9 days with an interval of 3 days (on the 4th day) 1 suppository 2 times a day after 12 hours. Then every 4 weeks until delivery VIFERON® 150,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. If necessary, it is indicated before delivery (from 38 weeks of gestation) VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 10 days.
Primary or recurrent herpetic infection of the skin and mucous membranes, localized form, mild to moderate course, incl. urogenital form in adults, including pregnant women. The recommended dose for adults is VIFERON® 1,000,000 IU, 1 suppository 2 times a day after 12 hours every day for 10 days or more for recurrent infections. According to clinical indications, therapy can be continued. It is recommended to begin treatment immediately when the first signs of damage to the skin and mucous membranes appear (itching, burning, redness). When treating recurrent herpes, it is advisable to begin treatment in the prodromal period or at the very beginning of signs of relapse.
Pregnant women from the second trimester of pregnancy (starting from 14 weeks of gestation) are recommended VIFERON® 500,000 IU, 1 suppository 2 times a day every 12 hours for 10 days, then 3 times for 9 days with an interval of 3 days (on the 4th day) 1 suppository 2 times a day after 12 hours. Then every 4 weeks until delivery VIFERON® 150,000 IU, 1 suppository 2 times a day after 12 hours every day for 5 days. If necessary, it is indicated before delivery (from 38 weeks of gestation) VIFERON® 500,000 IU, 1 suppository 2 times a day after 12 hours every day for 10 days.
Instructions for use
The medicine in suppositories is used rectally (the suppository is inserted into the anus). To insert suppositories correctly, you need to spread your buttocks and insert a suppository into the anus. After administering the medicine, you should lie down for half an hour. During this time the candle will dissolve.
Now we will tell you how to place a Viferon suppository rectally for a baby. For children, suppositories are administered in a position on their side (newborns) or on their stomach (children over 1 year). To administer the medication, spread the buttocks and insert a suppository into the anus. Next, squeeze the gluteal muscles and hold the child in this position for 2-3 minutes (since the candle may slip out). After administering the drug, the baby should lie down for half an hour.