In this article we will look at the Repleri line of fillers. What they contain, how effective they are and for what areas, how injections are made and what complications there may be. In addition, we will get acquainted with the opinions of cosmetologists and patient reviews, prices in Moscow clinics, photographs of patients before and after the procedure.
Repleri fillers
How do Repleri drugs work?
Hyaluronic acid is an important component in the human body. It is entrusted with the functions of regulating water balance and participating in the formation of elastin and collagen. In youth there are no problems with its synthesis, so the skin is elastic and smooth. With age, synthesis decreases, the first wrinkles appear, and the skin becomes dry.
Therefore, hyaluronic acid is introduced from the outside, this allows it to act directly on the required area.
How hyaluronic filler works
During the injection, Repleri gel fills the subcutaneous voids, thus smoothing out wrinkles and creating ideal contours. And due to the presence of hyaluronic acid in the composition, its deficiency is compensated. The result is hydrated, smooth skin, without sagging or wrinkles.
Advantages over other manufacturers
The manufacturer cites several main advantages over other fillers:
- Density. Repleri is a biphasic filler with particles of different sizes. This increases the density of the gel, so after injection it lasts up to a year and does not dissolve.
- When administered, no collagen is formed. This ensures that the client is not at risk of fibrosis after the procedure.
- Safety. The drugs are the most studied fillers among others on the Russian market. The studies were conducted both in an artificial environment and on patients. According to experts, injections are safe and create a long-lasting aesthetic effect.
- Wide range of applications. Repler 1 is used to work in the areas around the lips and eyes. Replery 2 - for getting rid of small wrinkles, lip correction, for non-surgical rhinoplasty. Repler 3 eliminates deep wrinkles, enlarges lips and adds volume to cheekbones. In addition, it is used in intimate contouring. Repleri 4 is used to correct cheekbones and the shape of the chin. The 5th is used in the same areas as the 4th, but it can be used for contouring of the nose. The Lip series is designed to correct the volume and contour of the lips.
About biorevitalizants Repleri Bio-R
Biorevitalization Repleri Bio-R is a course procedure. To achieve maximum effect, you need to undergo 3-5 sessions with an interval of 2 weeks.
Biorevitalization is carried out using the mesotherapy technique of multiple microinjections using a glass syringe of 30 G caliber. Please note: the new package must be opened in your presence and used completely.
Pros of Repleri Bio-R
- Lasting results lasting up to 1 year.
- Absolutely safe when used correctly and contraindications are followed.
- Effective against fine expression wrinkles.
- Low price relative to other biorevitalizants.
Special offer
Repleri №3 (1ml)
from 12,000 rub.
22,000 rub.
Make an appointment
How is the procedure done?
The procedure, together with local anesthesia, takes no more than 45 minutes. Sometimes several drugs are administered at once, depending on what purpose is being pursued.
Preparing for injections
Basic recommendations for preparing for contouring:
- refusal of drugs that reduce blood clotting 2 days before and after the procedure;
- abstaining from alcoholic beverages, visiting a sauna or solarium, 5 days before the injection. You cannot visit the solarium for a month after the procedure;
- taking homeopathic remedies based on arnica 5-7 days before the procedure and 2-3 days after. This will prevent bruising.
Administration techniques
The method of administration of Replery depends on which area is planned to be corrected and with what drug. There are four main techniques:
- Linear. Used when introducing a gel of medium density molecules into the upper layers of the skin. A thin needle is inserted to its full length at an angle of 30 to 40 degrees.
- Fan. Injections are carried out according to the principle of linear technology. The main difference is that the needle is not removed after injection, but is turned under the skin in the opposite direction. Next, the introduction of the gel continues.
- Mesh. The technique is used when working in the temporal part of the face, with cheekbones and cheeks. The gel is injected parallel and perpendicular, thus obtaining a soft filling effect.
- “Sandwich.” Used when working with deep changes on the facial skin. The gel is introduced in two stages onto different layers of the dermis. The needle enters the deep layers at an angle of 30 degrees, and into the upper layers - 15 degrees.
Procedure step by step
Let's look at the step-by-step procedure using the example of cheekbone and lip augmentation with Repleri filler:
- Cosmetics are removed from the skin, and the area where the gel is introduced is disinfected.
- The drug administration is marked.
- An anesthetic cream is applied.
- The packaging with the drug is opened and the expiration dates are checked. Everything happens in the presence of the client.
- Administration of the drug.
- Repeated skin disinfection.
- Light massage, application of an anti-inflammatory agent.
Replery
Life in the modern world constantly pushes us to improve not only our intellect, but also our appearance. The pursuit of ideal, preservation of youth, constant struggle with the nature of aging is the driving force behind the development of modern cosmetology and aesthetic medicine.
Repleri fillers are injectable preparations based on hyaluronic acid , which can be used to prevent age-related skin aging, as well as correct facial contours, smooth out wrinkles, and add volume and sensuality to lips. Due to their quality and availability, they have become very popular both among cosmetologists and their patients.
What are their differences from their analogues and for what other purposes can they be used? Who is the procedure indicated for, when does the result appear and how long does it last? Are there any contraindications, are there any side effects? TecRussia.ru finds out all the important details:
↑ Who is the manufacturer?
- This line of gels was developed in 2005 by the Russian LLC NovoNexus - it produces its own products for use in cosmetology: fillers, biorevitalizants, a line of cosmetics, a wound healing agent and software for simulating the results of contouring. Also, the company organizes sales through a distribution network and training seminars for doctors.
- Due to the lack of the necessary high-tech equipment in our country, Repleri production is located in China (in the city of Shanghai). According to NovoNexus representatives, this does not affect the quality, but significantly reduces the final cost of the filler.
- In 2008, the drug received a certificate from Roszdravnadzor as an intradermal implant (registration No. FSZ 2008/03147) - this is a full-fledged registration option that fully complies with the requirements of Russian legislation.
↑ Features and indications for use
Like most modern fillers, the key element of Replery's composition is stabilized hyaluronic acid, which, due to its artificial origin, is hypoallergenic. Thanks to its wide range, the filler can be used both for contour plastic surgery and for mesotherapy and biorevitalization. The main problems that can be solved with its help are age-related skin changes caused by lack of hydration and loss of soft tissue volume. The main ones:
- nasolabial folds and wrinkles;
- wrinkles on the forehead, temporal region;
- folds in the bridge of the nose;
- wrinkles around the lips;
- puppet lines;
- contour deformation and loss of lip volume;
- lack of volume in the cheeks and chin;
- premature aging of the neck, décolleté, hands, etc.;
- the need to correct the earlobes and the shape of the nose.
↑ Line of fillers Repleri
The drug is available in 5 varieties, which are marked with numbers from 1 to 5. They differ from each other in density and particle size, which allows the cosmetologist to choose the best option depending on the purpose of the procedure. In addition, a separate series “Repleri Lip” is presented for working with the lip area:
Filler (No.) | Characteristics, indications |
1 | The gel particles are very small in size. Effective for biorevitalization of the skin, smoothing out small wrinkles and working with the most delicate areas - under the eyes, around the lips, etc. |
2 | It is used to eliminate the average depth of wrinkles, emerging nasolabial and labiomental creases, correct skin unevenness, and lip enlargement. |
3 | Indicated for working with the deepest wrinkles, creases, increasing lip volume, shaping the face contour, replenishing volume in the cheekbones and temples. |
4 | Designed to fill deep, loose folds, restore lost fatty tissue, and restore facial contours. The main areas of application are cheekbones and chin. |
5 | Used for the same purposes as No. 4, but gives an even greater increase in volume. Also, it can be used to perform non-surgical correction of the shape and size of the nose. |
Lip | Designed specifically for lip augmentation, it allows you to give them characteristic plumpness and fullness, create the correct contour, and correct asymmetry. |
↑ How does Repleri differ from other injection gels
According to NovoNexus representatives, their drug has several important advantages over other gailuronic fillers:
- High density and biphasic structure of HA. Due to this, the filler retains its shape better, and the resulting effect lasts longer. However, some cosmetologists argue that this structure has its drawbacks - in particular, to obtain a good aesthetic result after the main procedure, additional correction is almost always required.
- No fibrosis after injections. The manufacturer is confident that its product does not lead to the formation of type 1 collagen, which is considered the main cause of this complication.
- A large number of clinical studies. Currently, Repleri is the most studied of Russian drugs. At the same time, experts conducted not only experiments in an artificial environment, but also observations with the participation of real patients, in which both the aesthetic results and the safety of the gel were assessed.
- Wide range of applications. In addition to the traditional smoothing of wrinkles and lip augmentation, the drug has proven effectiveness for working with cheekbones, chin, and non-surgical rhinoplasty. Since 2011, Replery No. 3 has been approved for use in gynecology for the treatment of stress urinary incontinence, in sexology - to achieve vaginal orgasm in women and increase the duration of sexual intercourse in men, in ophthalmology - to eliminate soft tissue deficiency in anophthalmos.
Photos before and after injections of the drug Repleri: | |
↑ How injections are carried out
Only dermatologists, cosmetologists or plastic/maxillofacial surgeons can work with this drug. The procedure is performed in small stages, during each of which only one problem area is treated.
- During an in-person appointment, the cosmetologist finds out the presence of indications and contraindications, selects the desired filler from the Replery line, determines the dosage and injection points. Immediately after this, if the patient has no health restrictions, you can begin injections.
- The doctor removes makeup and natural impurities from the target area, applies an antiseptic and anesthetic cream. Local anesthesia is necessary, since the injections cause unpleasant painful sensations, especially when correcting the lips and mouth line.
- In the presence of the patient, the filler package is opened, the syringe is equipped with a thin needle, and the doctor begins to give injections. Their technique and depth may vary, depending on the problems being solved. Gels No. 1-3 are injected into the upper and middle layers of the dermis, and 4 and 5 - closer to the periosteum.
- The average injection time ranges from 30 minutes to 1 hour. Upon completion, the skin is re-treated with an antiseptic, a soothing mask can be applied to it, and a cold compress can be applied to the injection sites to reduce swelling.
For 2-7 days after the procedure, slight swelling and itching may remain in the treated area, which then goes away on its own. During this period of time, you should not visit the sauna, solarium, swimming pool, expose your skin to sunlight or use decorative cosmetics. The manufacturer promises that the resulting effect, depending on the number of the drug used, will last up to 18 months. However, patient reviews indicate a slightly shorter period - about 4-6 months, which corresponds to the results of other hyaluronic fillers.
Lip augmentation and chin correction using Replery No. 1 and No. 4: | |
↑ Contraindications for use, possible complications and side effects
The main factors that exclude the possibility of injections:
- individual intolerance to individual components of the gel;
- pregnancy and breastfeeding;
- bleeding disorders;
- autoimmune diseases.
Also, due to the nature of its structure, Replery is not suitable for working with the forehead and neck area. Preparations No. 4 and No. 5 cannot be used for lip augmentation. But the likelihood of an allergy to hyaluronic acid and other components of the gel is extremely low - so far no such cases have been recorded and a skin test before injections, as a rule, is not carried out. Known side effects are mainly associated with the injection method of administering the drug, appear immediately after the end of the session and disappear in a short time (up to several days) without additional treatment. It can be:
- bruises and small bruises at the puncture sites;
- redness and pain in the treated area;
- swelling that lasts no more than 5 days.
No specific complications were identified when using these gels, however, when using them, all the problems that can cause any hyaluronic fillers are possible. In particular, patient reviews mention:
- persistent swelling - a likely cause is the incorrect selection of the drug, for example, when a too dense gel is injected into the area under the eyes (see the article “How to remove puffiness after hyaluronic acid”);
- the appearance of characteristic “balls” and seals, most often in the lips - usually due to incorrect injection technique;
- acute inflammatory reactions - occur if pathogenic bacteria were already present in the body or got there due to violation of aseptic rules during the procedure. Injections can activate this process, but HA itself and the stabilizers included in the drug are not to blame for this;
- see also the article “Complications after contouring”.
↑ How much does Repleri filler cost? Current prices
The patient's expenses will depend on which product from the line the cosmetologist uses (the denser the more expensive). On average, compared to other brands, especially European ones, these fillers are noticeably cheaper.
Filler (No.) | average price | Range |
1 | 9.525 | from 7,000 to 12,900 rubles per 1 ml |
2 | 10.209 | from 8,000 to 15,508 rubles per 1 ml |
3 | 11.662 | from 7,800 to 35,000 rubles per 1 ml |
4 | 12.307 | from 9,200 to 21,000 rubles per 1.5 ml |
5 | 14.776 | from 9,200 to 26,000 rubles per 2 ml |
Lip | 10.300 | from 9,600 to 11,000 rubles per 1 ml |
Exactly how much of the drug is required is determined by a specialist during a personal consultation. At the same time, depending on the existing problems, it may be necessary to use several types of gel at once.
↑ Opinion of TecRussia.ru:
- Repleri is produced and sold by a company with a good reputation. The filler is designed in full compliance with Russian legislation; an impressive number of scientific studies have been conducted on it, confirming its effectiveness and safety. The range is quite wide and universal.
- Since this gel has been on the market in the Russian Federation and neighboring countries for a long time, there are quite a lot of reviews from both cosmetologists and patients who have tried it on themselves - some of them are both positive and negative. However, the latter, as a rule, are reports of various side effects and complications characteristic of injection cosmetology in general, and not associated with a specific brand.
- We recommend Replery to those who would like to reduce their costs for contouring, but are not willing to take risks by choosing inexpensive Asian fillers. It is important to remember that the biphasic structure of the gel requires special skills in planning and carrying out the procedure, therefore, for the best result and minimal risk of complications, injections should be done by a cosmetologist who has been trained and has experience working with this type of drug.
Repleri Security
Replery is the most studied drug in Russia in comparison with other fillers. Every year since 2008, it undergoes clinical trials.
Since 2022, additional analysis has been carried out in China according to international standards. Each new batch is tested on 100 volunteers. Half are doing the correction for the first time, the other half are doing it again. The filler is injected into the chin, lips, nasolabial folds, nose, cheekbones, and periorbital area. Company experts monitor patients for six months. Communication with patients occurs through a special application. After ensuring quality and safety, Repleri is sent to Moscow.
Repler is one of the most studied fillers in Russia
In addition, the company offers training for cosmetologists and the use of the PatientStory application to quickly respond to all requests and the patient’s condition. The main values of the company: positive customer history and repeat business.
The use of non-animal hyaluronic acid in Repleri fillers makes them completely safe. Allergic manifestations are excluded. Injections, unlike synthetic implants, do not cause negative consequences.
And if you don’t like the result, everything will return to its original state within a year. This is possible due to the fact that hyaluronic acid completely disintegrates.
To achieve an ideal result, you need to choose the right Repler number. Adhere to the technique of inserting and deepening the needle. Failure to comply with these two factors can lead to poor filling of wrinkles and incomplete aesthetic effect.
Video: How Repleri is made
Possible complications and side effects
No specific complications were identified with the use of Repleri drugs. Side effects include:
- swelling, which could be caused by the wrong choice of the drug series;
- the appearance of seals or balls occurs more often with lip augmentation. The reason is a violation of the introduction technology;
- inflammation is possible if the rules of asepsis are not followed or if the process of inflammation began even before the procedure. Hyaluronic acid itself is not capable of causing suppuration, but can become an activator of the process.
Injections using Repleri intradermal gels can only be performed by qualified specialists: cosmetologists, dermatologists and maxillofacial surgeons. A reliable doctor is the key to a healthy and safe procedure.
Contraindications for use
All Repleri products based on stabilized hyaluronic acid are absolutely biocompatible with human tissues and are subject to natural biodegradation in the body, which has been proven by clinical trials and many successfully performed procedures.
However, there is still a general number of contraindications that exist for the use of such filler drugs: these are allergic reactions to its components, autoimmune diseases and blood clotting disorders.
In each individual case, additional consultation with a doctor is required.
Cosmetic procedures are contraindicated during pregnancy and lactation.
Compatibility with other fillers
Sometimes the question arises with what other fillers can Repleri be safely combined so that it is safe but effective. The answer is simple, any two-phase preparations with the main active ingredient in the form of hyaluronic acid.
Here is a list of some of them:
- Restylane - eliminates the absence of soft tissues, used in the correction of wrinkles;
- Perlane contains stabilized particles of sodium hyaluronate. The gel is used to correct the shape of the face and fill deep folds;
- Perfecta is an implant of biotechnological origin. It is used for modeling lips, facial contours and skin plastic surgery.
Indications for use
- Dry skin, feeling of tightness;
- dull skin color, decreased turgor;
- fine wrinkles around the eyes, mouth, neck and décolleté, and hands;
- presence of the main signs of skin aging (sagging, age spots).
Article on the topic
Hyaluronic acid for the eyes - how to choose the right drug?
Preparations containing hyaluronic acid are as numerous as the purpose of the procedure itself. Which drug is better to choose and who to trust with the choice? Let's try to look at these key questions.
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Cost of injections in Moscow clinics
Clinic name | A drug | price, rub. |
CLINICA IDEAL | Repleri No. 4 – 1.5 ml | 14 000 |
Repleri No. 5 – 2.0 ml | 15 000 | |
MedCenterService | Repleri №2 – 1ml | 10 350 |
Repleri №3 – 1ml | 11 000 | |
Medical cosmetology clinic "Aida" | Repleri Lip – 1ml | 16 000 |
Repleri №1 – 1ml | 15500 | |
Repleri №2 – 1ml | 15500 | |
Repleri №3 – 1ml | 15500 | |
Repleri №4 – 1.5ml | 17500 | |
Repleri №5 – 2ml | 23000 | |
Medical-surgical | Repleri №3 – 1ml | 11500 |
Repleri №4 – 1ml | 13500 | |
Repleri №5 – 2 ml | 17000 | |
Arbat Esthetician, expert cosmetology clinic | Repleri №1 – 1ml | 11600 |
Repleri №2 – 1ml | 11600 | |
Repleri №3 – 1ml | 11600 |
The price of the drug depends on its density; in comparison with other brands, Ripplery is a little cheaper.
Only a cosmetologist determines how much and what kind of drug is needed for correction. It is possible that several fillers will be used at once.
Repleri – Price in our clinics
Repleri №3 (1ml) | Price: from 12,000 rub. | Price: 22,000 rub. |
Repleri №4 (1.5 ml) | Price: 16,500 rub. | Price: 31,000 rub. |
Repleri №5 (2 ml) | Price: 19,900 rub. | Price: 37,000 rub. |
Repleri is 2 lines of drugs developed by the Russian company.
The first series of drugs appeared on the market in 2005 and, thanks to their high efficiency and safety combined with a fairly low price (production is carried out in China, production costs are correspondingly lower), they became in demand and popular among thousands of cosmetologists and patients.
Repler is one of the 5 safest fillers in the world.
Currently, the biorevitalization line is represented by the following drugs:
- Repleri Bio-R15,
- Repleri Bio-R20,
- Repleri Bio-R23,
- Repleri Bio-R30.
They differ in the concentration of hyaluronic acid of non-animal origin. The most popular (due to its versatility) is Bio-R 20.
The line of fillers for contour plastic surgery includes the following preparations:
- Repleri 1,
- Repleri 2,
- Repleri 3,
- Repleri 4,
- Repleri 5.
Gels have varying degrees of viscosity and solve problems of varying specificity and complexity - from eliminating small wrinkles to serious correction of facial volumes (contouring of lips, cheekbones, chin, etc.).
Nomosclinic no longer offers contouring procedures using Repleri fillers. Now we use fillers Hafiller Derm Deep, Juvederm ultra, Surgiderm, Teosyal and others. You can view the full list on the “Prices” page.
Correction of nasolabial folds using the drug Repleri 4.
Photos before and after
Photos before and after lip augmentation Repleri No. 1
Photos before and after correction of lower corners with Repleri filler
Photos before and after Repleri reconstructive contouring (cheekbones and chin)
Photos before and after complex contour plastic surgery Repleri (cheekbones, temples, chin, eyebrow lifting, forehead lifting, non-surgical rhinoplasty)
Photos before and after chin augmentation Repleri No. 5
Photos before and after lip correction – 1 ml Repleri No. 3
Areas of use
Contour plastic
Replery filler was developed primarily for contouring. With its help, you can adjust the shape and volume of the lips (in particular the borders), change the shape of the bridge of the nose, earlobe, chin and cheekbones, and get rid of jowls. The intradermal filler smooths out fine and deep forehead wrinkles, provides non-surgical lifting of the eyebrows and temporal zone, eliminates nasal and marionette folds, and eliminates perioral folds.
Cosmetologists' opinions
Basically, cosmetologists speak positively about Replery gels. Specialists are attracted by the price-quality ratio. But there are those who do not trust, citing the production of the gel in China.
For example, a cosmetologist is completely satisfied with the line and actively uses it in practice.
And this cosmetologist uses Repler 4 and 5 in his work, but emphasizes that the effect of fillers is less compared to others.
Another cosmetologist compares Replery with other fillers and recommends choosing a good doctor, not a clinic.
Patient reviews
Among the patients there are those who are not the first to enlarge their lips and were in search of their own remedy. But it is Replery that becomes a permanent drug.
For a quick result and long-lasting effect for lip correction, the patient, on recommendation, chose Replery and was satisfied.
Another patient had her nasolabial lips corrected; she is familiar with the entire line of fillers and knows the manufacturer. I'm happy with the result.
Here the woman also had her nasolabial folds corrected. In the review she writes that she is satisfied with the result and believes that this is a good drug. It also notes a lasting effect.
Popular questions
Are injections a painful procedure?
Yes, the procedure is painful, so it is performed with anesthesia.
Are the injection sites visible?
Redness at the injection site, slight itching, and tension may appear. The injection mark and swelling disappear after a few days.
What does your face look like after Repleri cheekbone correction?
The effect is visible immediately after administration of the drug, but you can evaluate the final result after 14 days. During this period, the swelling will subside, and it will be clear which areas require additional correction.
How to get rid of swelling faster?
Immediately after the injections, apply ice and use medications prescribed by your doctor. In the case of lip correction, you need to smile less and avoid the sun.
How does skin sensitivity change?
Sensitivity does not decrease; there may be a slight decrease only immediately after the injection.
Does facial expression change after injection?
If the injection technique is followed, the facial expression will remain the same.
How long does the effect of the procedures last?
The drug is absorbed gradually. The effect disappears after 5-12 months, depending on the filler and injection site.