Application of Azelik gel for acne, blackheads, post-acne, comedones and rosacea

Azelik is perhaps one of the most effective and frequently prescribed remedies for acne and acne on the face. When used correctly, you can significantly speed up the cleansing of skin rashes, as well as prevent new ones. The drug, due to its azelaic acid content, copes well with inflammatory processes that arise in the epidermis.

Azelik's action

The gel quickly penetrates the epidermis and has a number of beneficial effects:

• moderate anti-inflammatory;
• antioxidant;
• antimicrobial;
• antikeratic (prevents the coarsening of the epidermis and the formation of “goose bumps”);
• anti-pigment;
• sebum-regulating.

Its active ingredient, Azelaic acid, is a natural compound for the skin, formed during the oxidation of fatty acids. Due to this degree of “relatedness”, this substance penetrates well and quickly into the epidermis, but does not directly harm the cells themselves. For this reason, Azelik is safe, and most importantly, can be used for a long time. On the other hand, a long course is also possible due to the lack of formation of microbial resistance, as, for example, often occurs in bacteria to antibiotics.

Indications for use

According to the instructions for use of Azelik, there are only 2 official indications, namely:

• mild to moderate acne
• rosacea, including papulopustular form.

However, the spectrum of action of the drug is not limited to this. It can be used to treat acne, purulent and subcutaneous, fungal (as part of combination therapy) and microbial nature, blackheads and hair follicles not only on the face, but also on the back and other parts of the body.

AZELAIC ACID, SULFUR AND ZINC - A TRIPLE IMPACT FOR ACNE

Bottles with a red stripe and the inscription AZELAIC present the most effective products in the Seracin LIBREDERM line. They contain a complex of three components, which completely helps against acne.

Azelaine has pronounced anti-inflammatory and antimicrobial properties, normalizes sebum production, which has an anti-acne and depigmenting effect on the dermis and epidermis.

Also, as in the rest of the Seratsin LIBREDERM , there are specially developed components based on natural sulfur and zinc salts. They have sebum-regulating, antibacterial and local anti-inflammatory functions.

No less important are the additional components in the line:

- burdock extract and gulavnik extract - sebum-regulating and antibacterial effect, - finger lime extract - cleansing and antioxidant effect, - BIOLIN prebiotic - supports the natural microflora of the skin.

After using cosmetics with such a composition of components, acne has no chance of survival. Seracin LIBREDERM collection of products acts on the skin like a life-giving elixir, transforming it from sick and irritated to healthy and smooth. Always be well-groomed and beautiful!

Contraindications

Azelik has only one general contraindication:

• hypersensitivity to the components of the drug.

As well as contraindications due to age:

• +12 years for acne treatment;
• +18 years - for the treatment of rosacea.

In children aged 12 to 18 years, Azelik® is used in the treatment of acne; no dose adjustment is required.

https://azelik.ru/instruktsiya/

So, if you doubt whether this drug can be used for a teenager, here is official confirmation - it is possible.

Also, I would not recommend the use of drugs with azelaic acid during pregnancy and breastfeeding. Because, according to research, it enters the systemic bloodstream. However, I have not found any evidence that the active substance can penetrate the placental barrier, but I am inclined to believe that it can more often than not.

Side effects

Despite the general safety of the drug, even in adolescents, all sources contain a lot of information about side effects. It’s good that it’s accessible and not hidden.

Here are some of them noted by people themselves:

• after applying the gel itching appears;
• burns the skin;
• stings the face;
• redness and irritation appear;
• peeling appears;
• The strangest thing is that even more acne appears.

What does the manufacturer write about this?

at the beginning of treatment, local irritation, hyperemia and peeling of the skin, burning, erythema, itching are possible, which usually cease during treatment; Possibly allergic skin reactions.

In many ways the same thing, it turns out that people are warned before use about possible side effects, which usually go away with further use. And how to prevent them from appearing or causing discomfort, read in the Application section.

Summarizing the above, I can say that clear contraindications are allergic reactions, especially of the immediate type: urticaria, Quincke's edema, etc.

After information about possible side effects in the form of dryness and flaking of the skin, the hand will involuntarily reach for a moisturizer. But not so fast! Not every cream will do. It is necessary to give preference to non-greasy creams without comedogenic components. After all, Azelik is used to treat existing pimples and there is no need to clog the pores with cream in order to also treat new pimples. An alternative to creams are fluids, milks and gels. Preference should be given to cosmetics that are suitable in composition, possibly pharmacy or professional cosmetics.

About correct use

Before applying Azelik to your skin, be sure to remove all makeup with a product specifically designed for this purpose and wash your face with a good cleanser.

If there are a lot of large acne vulgaris at the site of inflammation, it is recommended to wash such lesions with boric, sulfur or tar soap after the cleansing gel. After washing your face, pat your face dry with a clean paper towel to remove excess moisture. Now you can start applying.

Application

If you have acne, the first thing you should think about is hygiene. This is not only a wash, but also applies to everything that touches your face:

• scarf;
• jacket hood;
• sweater collar;
• pillowcase;
• hands of course.

Therefore, after washing, while your hands are still clean, you can apply Azelik with your finger. But it is better to use a hygienic cotton swab or a special spatula for creams.

When applying the gel with your hands, be sure to take care that you do not have to get it from somewhere, touching everything in your path with your hands.

For the whole face or just for spots?

The method of using Azelik gel depends solely on the condition of the skin at the moment. Based on how many rashes there are, whether they are located in groups or individually, it depends on how to apply the product - completely over a large area and the entire face or to problem areas individually.

When applied to healthy dermis, of course, there will be no harm (in rare cases, dryness may only appear). However, the consumption of the gel will increase by an order of magnitude, and it will run out faster. To avoid this, follow the rule: the pimple should be completely covered, but no more.

When absorbed, the drug will be slightly distributed over the surrounding area. Remember that a large amount of azelaic acid applied at one time will not replace its systematic application.

To rinse or not to rinse, that is the question...

Those who use Azelik for the first time may have a logical question about whether it needs to be washed off? Let's figure it out.

There are two fundamentally important points:

• the first is the adaptation of the skin and possible, although infrequent, allergies, and much more frequent chemical burns and irritations at the beginning of treatment;
• the second is the cumulative effect of azeleaic acid, i.e. the drug with it will be more effective, the more acid accumulates in the lesions (and microbes, by the way, too!).

Therefore, if you experience irritation and the feeling that a chemical burn has occurred, then the product must be washed off. Otherwise, it should not be washed off.

Application frequency

According to the instructions, Azelik must be applied to the affected area 2 times a day: morning and evening. There is no point in applying it more often; in this case, there will be no clinically significant improvements, but you can easily dry out the epidermis. In addition, it is also necessary to emphasize hygiene and proper skin care.

If treatment with other local drugs is carried out simultaneously, the final result will depend on the drugs themselves. In this case, application can be either joint or separate, and the frequency range is from 1 to 2 times a day. More details about combinations are written below in the “Analogues” section.

About the course of treatment

The duration of use of the drug directly depends on the condition of the skin and the frequency and extent of rashes. The more there are, the proportionally and longer the gel will have to be used.

You shouldn’t be afraid of this, azelaic acid has a beneficial effect on the epidermis (if you don’t have allergies, and you will know about it right away) and it can be used for a long time, including several months in a row. In this case, it is better for teenagers to consult a dermatologist. After the course, it is necessary to take a break before repeating the course of treatment, but sometimes it happens that the skin is healed and the need disappears.

Azelik gel for external use approx. 15% 30g Akrikhin/Russia

Important. If the location “Online Pharmacy” is selected in the site menu, ordering the product is possible only at the “Price to order” based on suppliers’ offers. If suppliers do not have goods, only the “Subscribe” option is available if the old price is known, or “To order” when there is no information on the old prices. We ask you to pay attention to the “Availability” Tab - you can order goods at the balances and prices of pharmacies, but to do this you need to select the desired pharmacy in the site menu (next to the “Your pharmacy” field).

This section provides answers to frequently asked questions from visitors to our site.
Can I get an additional discount?
There are no discounts on the site.

We simply gave up discounts and set a minimum markup on goods, and try to keep prices at such prices that it turns out even cheaper than with the maximum possible discount, and these prices are for all our customers. Accordingly, the discount does not apply to online orders made through. These orders are already at the minimum price, since when ordering, the minimum price is automatically selected from the price at the pharmacy and the price to order. Usually the price “to order” is cheaper than in a pharmacy, it comes to order, with a guarantee of quick redemption, and accordingly the markup is lower than in a pharmacy, since there is no need to keep the goods in stock. If the product is available in the pharmacy and the price in the pharmacy is cheaper, then we take the pharmacy price for this item as a basis.

Can I change my order after I have submitted it?

Adjustment of goods, quantity, change of point of issue, etc.
after you send your order is possible only by the manager after we receive the order, when the manager contacts you to clarify the order. In the buyer's personal account, only the ability to cancel or repeat orders is available. To adjust your order, you need to contact the contact manager of the pharmacy - the order pick-up point indicated on the “Contacts” page of the website. Can I contact the pharmacy myself to find out if my order has arrived?
You can call the pharmacy using the numbers listed on the website.
OUR PHARMACIES, ADDRESSES, TELEPHONES What will happen to my order if I don’t buy it within 5 days, and when can I pick it up later?
If you have not purchased your order within 5 days, your order will be canceled and the product will be put up for sale at the retail price in the pharmacy. And you will have to make a new order on the website.

If you ordered a product on the website and did not come for it within 5 days from the date of receipt, your data will be blacklisted (emergency), and a new order will be possible only after making a deposit on the order in the amount of 30% of its cost. If you refuse to purchase your order, the deposit amount will not be returned.

When you first add to an emergency situation, a warning is sent that the next time you find yourself in an emergency situation again, you will not be able to place orders.

Those buyers who systematically do not redeem their orders on time, as well as those who do not buy all the goods from the order, but only part of them, also fall into emergencies.
If I cannot pick up my order on the day it arrives at the pharmacy, can I redeem it later?
Your order is stored in the Pharmacy for 5 days from the date of receipt, during which time you can pick up your order.
When can I receive my product after ordering?
After sending the order, an SMS message about the order will be sent to the mobile phone number you specified, for example: “Zdravstvujte, Vladimir! Vy oformili zakaz No. 1234 na summu RUR 2345.50 Ozhidajte zvonka iz apteki.”, then during the working day, from 9-00 to 17-30, the APTEKA-INFO.RU service manager will contact you to confirm your application, then the application will be sent to the supplier , will be collected there and delivered to the pharmacy of your choice on the next business day.

Important.

Applications are processed only on weekdays from 9-00 to 17-30.

Applications accepted and processed on Friday will be delivered to the pharmacy on Monday or Tuesday. It is possible to speed up the order readiness; the exact date of order readiness is agreed upon with the manager. Applications received on weekends (Saturday, Sunday) will be accepted and processed on the next business day, and delivered on Tuesday-Wednesday.

When agreeing on an order, we warn you about the approximate time frame for the entire order to be ready in order to avoid misunderstandings.
How will I know that my order has been delivered to the pharmacy?
When the goods arrive at the pharmacy, you will receive a letter about the readiness of your order and an SMS notification, then they will call you and inform you that you can come and pick up your order. If you do not redeem your order within 1-2 days from the moment it is ready, they will call you and remind you that it is ready.

Important.

All letters and SMS are sent automatically when the status of the order changes, but sometimes situations are possible when the letter and SMS are ahead of the delivery of your order to the pharmacy, mainly due to an error by the workers processing the order.

A phone call from the pharmacy is a 100% guarantee that your order has already arrived at the pharmacy and you can receive it. So please wait for this call.

If you want to clarify the status of your order, you need to call the pharmacy where the order is issued and provide your name and order number.
Is it possible to pick up the ordered goods?
Pickup is the main way to receive an order on our service, since most orders contain medications that we cannot deliver to you by courier.
You can independently pick up the ordered goods at our pharmacies - delivery points, this is convenient, we have 4 pharmacies in Tomsk and 1 in Seversk. How is delivery to the regions carried out?
Delivery to regions is not possible.
We work only in Tomsk and Seversk. Is it possible to order medicine to be delivered to your home?
The delivery of prescription drugs is prohibited by the current legislation of the Russian Federation.

Delivery of over-the-counter medicines is permitted only if there is a license for the remote sale of medicines.

APTEKA-INFO is working to resolve the delivery issue, but unfortunately we do not yet have the necessary license, so home delivery is not possible.

We deliver orders containing medications only to our pharmacies.

You can choose any pharmacy convenient for you from those presented on and redeem your order at the selected pharmacy.

There are prescription drugs on the site, can I order them and get them at the pharmacy?

You can order prescription goods, but when purchasing from a Pharmacy for any prescription drug, you have the right to require a prescription, and if you do not have a prescription, the Pharmacy has the right not to issue your order. When confirming an order by the buyer at the stage of its pre-processing, the service manager usually always checks whether the buyer has a prescription; if it is not available, prescription products are excluded from the order. The items in your order are not a single item, and you will be able to receive over-the-counter drugs included in your order.

Attention!

Buyers who regularly fail to redeem part or all of their orders risk being blacklisted. If a buyer is blacklisted, a restriction is included - when ordering rare drugs and goods, the pharmacy has the right to demand from the buyer:

1) making a deposit - if, when the buyer refuses to buy these goods, the service has problems with further sales, since the goods are very rare, are not in rare and everyday demand, or the supplier refuses to return such goods. The deposit amount in this case is not refundable.

2) making an advance payment - if the product is rare, but it is still bought by ordinary customers in pharmacies.
Making an advance payment in this case is an additional guarantee that the buyer really intends to purchase this product. In case of cancellation of the purchase, the advance payment is returned to the buyer in full. Why do “to order” prices on the website differ from prices in pharmacies?
We try to keep prices minimal for our clients, so prices for drugs on our website are usually lower than in pharmacies and apply only to online orders made on the website.

The “made to order” price is formed based on suppliers’ proposals. Prices in a pharmacy are individual, since prices from suppliers change every day, all pharmacies work independently and receive goods on different days and months, so prices in pharmacies are all different. If you urgently need medicine on the same day, and at a low price, you can find information about the availability and prices of the product on its page, in the “Availability” tab, there is information about stock and prices in our pharmacies.

How can an organization purchase medicines and goods?

Due to the introduction of labeling for drugs, a large number of labeled drugs, and the lack of profitability of this activity, we are forced to stop working with legal entities on drugs that have a labeling sign.

Therefore, on our website, legal entities can no longer purchase medicines and medical products by bank transfer.

The opportunity to register and place orders remains available for legal entities. But working by bank transfer and receiving sales and accompanying documents for orders is impossible.

We continue to accept applications from medical centers, hospitals, medical institutions, medical units, beauty salons, private offices, etc., who need medicines and over-the-counter medicines and other goods and medical products that do not have a label, as well as parapharmaceutical products for “own needs”, as well as from organizations that maintain their production first aid kits fully equipped.

Our conditions and a brief procedure for working with legal entities:

1. The minimum order amount for legal entities was previously 3,000 rubles, now it is 400 rubles.
2. The purchasing organization registers on the website apteka-info.ru, where it can then create an order.
3. To receive information about the order and its approval, the purchasing organization sends a request to the email address and also provides the order number.
4. A supply agreement is not concluded with a legal entity, since the purchasing organization buys the online order in cash, at retail, in the same way as ordinary buyers - individuals.
5. After receiving the order and agreeing on the terms of sale of medicines and other goods, APTEKA-INFO LLC accepts the online order and orders the goods from suppliers.
6. After receiving the goods from the supplier, the order is collected and prepared for delivery.
7. The delivery of the goods occurs after its preparation and assembly, pick-up at the addresses of the pharmacies of APTEKA-INFO LLC. The purchase period for the order by the buyer is 7 days from the date of readiness. Only cash receipts and sales receipts are provided with the goods. Certification documents for goods are provided upon special prior request.

You can also place an order:

• by sending a letter to
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Our specialist will advise you on the products, check their availability and calculate the cost of the order.
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Methods of using Azelik

The choice of method of application is based on the number of rashes and their severity. For a full effect on the skin, it is necessary to use the drug correctly.

For acne

Azelik is one of the most popular and often prescribed by dermatologists for the treatment of acne. Since it is not addictive, and it is well tolerated and has a high safety profile, it can be used both for single pimples, in people who do not suffer from skin diseases, and for massive lesions, for example, in people with acne.

This drug shows good results both in the treatment of subcutaneous acne and inflammation with a protruding purulent head. Because it acts on a very wide range of microorganisms (like many antibiotics combined). But its effect is bacteriostatic (inhibits the growth of bacteria), and therefore is not a panacea.

For acne

Acne is a type of acne that is more severe and is classified as a separate disease. It is also referred to as acne if the causative agent is C. acnes (can also be staphylococcus and others). Azelik for acne is prescribed if the severity of the disease is not higher than average and, as a rule, as part of complex therapy, so that such treatment is truly effective.

For acne itself, the drug is one of the drugs of choice, in mono- or complex therapy, since its high activity against these particular bacteria has been proven.

For comedones and blackheads

Azelaic acid, which is part of azelica, lightens blackheads well. However, this only happens until you stop using it. After all, these formations are constantly being formed, therefore the fight against them must be regular. To get the maximum effect, you need to pay attention to proper and regular cleansing of the epidermis and nutrition.

This remedy is also quite effective in the fight against comedones. Moreover, both with inflamed forms (without pus), subcutaneous forms, and ordinary dark sebaceous plugs.

For post-acne and age spots

Azelik is one of the most effective * drugs for lightening pigmentation, and more specifically for post-acne and age spots of other origin. Including seborrheic nature. This drug evens out skin tone by affecting pigment cells - melanocytes, as it normalizes their work. Also by improving the processes of cell renewal and exfoliation, preventing keratinization.

TREATMENT AND CARE STRATEGY FOR PROBLEM SKIN

Proper cosmetic care for acne-prone skin has its own laws and consists of several necessary stages. Special care cosmetics should:

- relieve inflammation, - restore the skin barrier, - regulate sebum production, - effectively and long-lastingly moisturize the skin, - protect from ultraviolet radiation, - fight pathogenic bacteria, - help the beneficial skin microbiome.

The good news is that the products from the Seratsin LIBREDERM collection cover all these needs and are excellent for acne. It is important to learn how to use them correctly. For example, in the morning you need to first cleanse your face with a cleansing gel, apply a mattifying serum in the afternoon that fits well on top of cosmetics, and in the evening treat it with a night cream that normalizes the functions of the dermis during sleep. You can choose other items from the line, but the stages of care should take place in this order.

Analogs

This popular medicine has many analogues.

Among them are:

• analogues in composition or structure;
• according to the effect they have, having other active components - non-structural.

Analogs in composition contain azelaic acid as the main active ingredient. Only funds registered in Russia are listed here.

For convenience, we will divide them into:

• creams: Azix-derm;
• skinclear;
• skinoren.

Replacement for azelic in the form of the drug

Let's compare to find out how different forms of medicinal products will affect the properties. And we will draw a conclusion about which one will be more effective.

In the form of a cream

Among the identical products: Skinoren, Skinoklira and Azix-derma, there are slight differences in composition.

The first two products are almost 99% identical, but Azix Derm contains silicone oil and appropriate emulsifiers. This means that it is highly likely to clog pores. And overall the efficiency will be less. However, the drying effect on the skin will be less.

As a gel

To compare, as well as draw conclusions about which of them is better, Azelik, Skinoren, or Skinoklir and to understand their differences, we will use a summary table for a visual demonstration.

Azelaic acid for rosacea

Acne and rosacea are a common type of disease, especially prominent in the practice of dermatologists and cosmetologists. Diagnosis of the disease and choice of treatment are difficult. The prevalence of the chronic stage and severe psychological disorders are considered common. Reduces the quality of life of patients with rosacea. Therefore, choose only effective treatment and therapy. Very often, cosmetologists say that azelaic acid for rosacea is a method of treatment.

Azelaic acid in the treatment of acne

The mechanism affecting the pathology of rosacea is not fully understood. The first pathology is considered a chronic skin disease with redness. The formation of pustules and other types of rashes lead to a spoiled appearance. When studying the severe stage of the disease, which includes people of different categories: aged 18-65 years, it was found that approximately 5 percent of patients are residents of Russia, and 12 percent are residents of Germany.

Among all patients with the disease in both countries, women accounted for approximately 75%, with an average age of up to 40 years. Every person with rosacea had fair skin. The prevalence of the disease makes the face multi-colored, redness appears somewhere, and pink spots form. The skin is superior if treatment is started promptly. But due to the activity of sunlight in the regions, rosacea usually forms, ultraviolet radiation provokes the appearance of the disease.

Rosacea into subtypes:

• erythematotelangiectatic (subtype 1);
• papulopustular (subtype 2);
• phymatous (subtype 3);
• ophthalmic rosacea (subtype 4).

Preparations containing azelaic acid are considered a means to combat acne and rosacea. Azelaic acid targets the formation of new redness and blemishes, leaving skin softer and more hydrated.

Composition of the substance

Azelaic acid is a gel for external use. The active element is azelaic acid. The following auxiliary agents act as auxiliary components: benzoin acid – 0.1 grams; methylpyrrolidone - 4 grams; squalane - 1 gram; propylene gram glycol - 8 grams; disodium edetate - 0.1 grams; sodium gramhydroxide - 0.25 grams; dimethicone 100 cst - 1 gram; macrogrammol cetostearyl ether - 1.4 grams; carbomer interpolymer (type A) - 1.4 grams; purified water - up to 100 grams.

Description of the treatment procedure

The gel is white in color, but a slight odor is allowed. The consistency is medium and smooths out easily over the face.

Action

The drug has a direct effect on acne, therefore it is considered an anti-acne agent, which tends to influence the spread of acne or rosacea in general.

Pharmacodynamics

When treating acne, azeloic acid can normalize any disturbances in the follicles of the sebaceous gland. Additionally reduces the composition of free fatty acids released in lipids. It has a noticeable antimicrobial effect against Propionibacterium acnes or Staphylococcus epidermidis. The underlying mechanism of action of azelaic acid in the formation of rosacea has not been confirmed. One can only assume that the substance creates an anti-inflammatory effect, which is due to a decrease in neutrophil metabolism and a decrease in their production of free forms of oxygen. Acid has a dependent effect on the development of melanocytes.

Effect after applying the gel

As soon as a patient with a skin disease: acne or rosacea applies it to the skin, the drug penetrates deep into the epidermis, penetrates into the damaged area of ​​the skin, which happens quickly. Azelaic acid can be noticed after the first application. Everything depends only on the total dosage of the drug, which as a result enters the bloodstream. One part of the acid entering the body will mainly be excreted by the kidneys in an unchanged format, where one part is in the form of dicarboxylic acid, which can be formed in the form of beta-oxidation.

In what cases can azelaic acid be used?

Use of the substance in the formation of acne, moderate severity, with the appearance of papules and pustules. Rosacea, also with papules and pustules.

Contraindications

Excessive sensitivity to the drug and other contents. Age up to 12 years, up to 18 years with indications of rosacea. Use cautiously if you have bronchial asthma. Do not use for serious renal impairment.