Bioreparation procedure for the face-neck-décolleté area using HYALREPAIR®–04 Bioreparant

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Sharubina Karina Petrovna

Trichologist, dermatovenerologist, cosmetologist

Publication date: September 28, 2022

Review date: November 24, 2022

Biorevitalization is a procedure that instantly transforms the skin. From dry and lifeless, it will literally turn before your eyes into fresh, filled with youth, energy and beauty.

Biorevitalization is one of the most popular procedures in modern cosmetology. The name of this technique literally means “natural revitalization.” Biorevitalization helps improve the appearance of the skin, as well as slow down the process of its withering.

The technique involves the subcutaneous administration of drugs based on hyaluronic acid or other substances using thin needles or devices, which allows you to adjust cellular metabolism and recreate the extracellular matrix characteristic of a young body. The natural processes of regeneration and cleansing of the skin, its intensive hydration and nutrition are stimulated.

But it is worth remembering that biorevitalization is still not an ageless procedure. Its most optimal use is in the age range of 25–50 years. The older a person gets, the more difficult it is to compensate for the lack of hyaluronic acid in the skin; here it is already necessary to use other methods of skin rejuvenation.

Types of biorevitalization

Initially, biorevitalization was carried out only through injections. But over time, the technology of the procedure was improved. Now there are different types of biorevitalization.

Injection biorevitalization

Hyaluronic acid is injected under the skin using an ultra-thin needle. For pain relief, either special creams are first applied to the skin, or the drug contains lidocaine, a painkiller that has been proven over the years.

Non-injection biorevitalization (hardware)

Non-injection biorevitalization makes it possible to deliver hyaluronic acid deep enough into the basal layer of the epidermis without the need to cause any damage to the skin.

Laser biorevitalization

In fact, this is also a non-injection method, but it is distinguished separately because the laser has an additional effect on the condition of the skin. So, laser:

  • improves blood microcirculation, which increases the flow of nutrients and oxygen;
  • additionally stimulates the production of collagen and elastin;
  • eliminates inflammatory processes;
  • corrects minor flaws - uneven microrelief, post-acne.

Laser biorevitalization uses low molecular weight hyaluronic acid, which better stimulates the activity of fibroblasts compared to high molecular weight. It reaches the cells to a depth of 4 mm and is distributed as evenly as possible.

This method of facial biorevitalization has a pronounced effect, has a minimum of contraindications (can be performed even on inflamed skin) and practically does not cause complications.

Contraindications

Facial biorevitalization is not suitable for everyone. Sometimes it is worth holding off on injections, and in some cases, choosing a different method of rejuvenation.

  1. Pregnancy and breastfeeding. No specialist can be completely sure how the effects of the drug will affect the health of the expectant mother and the quality of breast milk. Due to weakened immunity during pregnancy, the skin may overreact to injections.
  2. Inflammation. First, it is better to wait for the wounds to heal, and then carry out rejuvenating procedures.
  3. Autoimmune diseases and other diseases in exacerbation. With multiple sclerosis, rheumatoid arthritis, and HIV, immunity is constantly under threat. Exposure to a chemically created drug may cause unexpected reactions or complications. If your illness is temporary - for example, you caught ARVI - you can come to the session after complete recovery.

Contraindications also include:

  • allergy to hyaluronic acid;
  • tumors;
  • diabetes;
  • epilepsy.

Moles are not an obstacle to anti-aging procedures. This is a common misconception. During the session, the drug is administered only to the area around the moles.

You should not carry out biorevitalization on critical days. Many procedures at this time are more painful.

Do not hide anything, otherwise the results of the sessions may disappoint you. Some of the best dermatologists in Lobnya work at the PrivatKlinik medical center, but without complete knowledge of the characteristics of your body, even they will not be able to provide you with ideal skin.

Preparations for biorevitalization

Biorevitalization with hyaluronic acid (the procedure is intended to moisturize the skin)

For the procedure, preparations based on hyaluronic acid are used. Injections allow you to moisturize the skin and activate natural biochemical processes in tissues. Hyaluronic acid is a natural moisturizer, so rejection of drugs based on it does not occur. Biorevitalization with hyaluronic acid also activates the process of collagen and elastin production. Due to this, wrinkles are smoothed out, the skin becomes elastic and smooth.

Peptide biorevitalization (promotes rejuvenation)

Peptides are special protein substances that trigger the process of cell renewal and restoration of their structure. Thus, peptide biorevitalization promotes rejuvenation.

Skinboosters (injections of stabilized hyaluronic acid)

These are injectable preparations that use stabilized hyaluronic acid - the molecules in the preparation are interconnected. Thanks to this, skin boosters have a long-lasting effect of moisturizing, smoothing wrinkles and lifting tissue.

Is rehabilitation needed? How long does the effect last?

After the procedure, medicinal cosmetics are applied to the face, which has a calming effect. It also strengthens the effect of hyaluronic acid.

The doctor assesses the condition of the skin and gives recommendations for care at home. They are standard:

  • Do not use decorative cosmetics for two days
  • Postpone physical activity, trips to the bathhouse, solarium, beach for 2 weeks
  • Do not drink alcohol for 2-3 days after the procedure
  • Try to drink as much clean water as possible
  • Wash with mild cleansers
  • Treat your face with the prescribed antiseptic

Biorevitalization gives a quick result, but how long it will last depends on heredity, the woman’s age, and the nature of the problems. On average, the effect of the procedure is noticeable within 6–12 months. To achieve a lasting effect, it is recommended to repeat the procedure several times. The quantity depends on the goals of biorevitalization:

  • preventive - 1–2 procedures;
  • therapeutic – from 5 sessions.

The interval is usually 2–4 weeks, more precisely determined by the doctor. Then, to maintain youthful skin, it is necessary to repeat facial biorevitalization every six months.

BIOREPAIR SESSION FOR CORRECTION OF AGE CHANGES IN THE "FACE - NECK - DECOLLETE" AREA

Target

Prevention and correction of aesthetic imperfections of the skin due to photoaging and age-related changes: smooth out superficial and deep wrinkles, moisturize, lighten pigment spots, strengthen the vascular wall, increase skin turgor and tone.

Indications for use of the drug

  • Correction of aesthetic imperfections of the skin due to photoaging and age-related changes: static wrinkles of varying severity, decreased skin tone and turgor, xerosis, rosacea, hyperpigmentation;
  • Prevention of hyperpigmentation of various etiologies;
  • Correction of post-acne (stagnant spots, post-inflammatory hyperpigmentation);
  • Improving complexion, eliminating dark circles under the eyes;
  • Protecting the skin from damage by aggressive environmental factors, including protection from the negative effects of UV radiation;
  • A sharp decrease in skin tone due to stress;
  • Preparation of the skin for plastic surgery, laser resurfacing, dermabrasion, chemical peels and skin rehabilitation after them.

Drugs

HYALRIPAIER®–04 Bioreparant (Lab. TOSKANI, Russia), 1.5 ml (Fig. 1)

; cleansing mousse with bromelain and papain Cleanser Mousse (Medic Control Peel, Lab. TOSKANI); local anesthetic; antiseptic; restoring cream with peptides Post Procedure Cream (Mesaltera by Dr. Mikhaylova, Lab. TOSKANI, Russia).

Equipment used:

needles 30G, 0.3 × 4 mm; needles 30G 0.3 × 13 mm.

Duration of the procedure:

40 – 60 minutes.

Recommended course:

three procedures every three weeks.

Supportive procedures:

once every one and a half to two months.

Before the procedure, the doctor conducts an examination, the patient fills out an informed voluntary consent to perform the bioreparation procedure and take photographs.

Preparation for the procedure

1. Makeup removal and exfoliation using Cleanser Mousse with bromelain and papain (Fig. 2)

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2. Application of a topical anesthetic to the skin under an occlusive film (exposure time 20 – 30 minutes) (Fig. 3)

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3. Double treatment of the skin with a 0.05% aqueous solution of chlorhexidine.

Pros and cons of the procedure

The main advantage of the procedure is that it can very quickly change the quality of the skin. Literally before our eyes, a transformation occurs: tired, dehydrated, dull skin instantly comes to life. If you look at the photos of patients before and after the procedure, the difference is enormous. It's like two different people.

Avdeyuk Elena Vladimirovna

Dermatovenerologist, cosmetologist

In addition, microtraumatization of the skin through injections or hardware helps to trigger the synthesis of collagen and elastin - the main building materials of the skin matrix, thanks to which it remains firm and elastic.

Many modern drugs used for biorevitalization also contain substances that have lifting, anti-inflammatory, healing and smoothing effects. Thanks to this, the skin tightens and various skin defects disappear.

The disadvantages of the procedure include the fact that it is effective until a certain age. In older age groups, laser, radio frequency and thread technologies are effective.

POST-PROCEDURAL CARE

  1. Skin treatment with 0.05% aqueous solution of chlorhexidine.
  2. Applying a restorative cream with Post Procedure Cream peptides (Fig. 13)
    , intended for the care of damaged skin. The cream has a pronounced anti-inflammatory effect, reduces swelling, reduces burning sensation and moisturizes the skin, resolves stagnant spots.

For quick rehabilitation after the procedure, the patient was prescribed restorative moisturizing cream Keladerm (Mesaltera by Dr. Mikhaylova). The cream has an anti-edematous effect, strengthens the walls of blood vessels and promotes the resorption of hematomas. White mulberry extract, which is part of the cream, reduces the activity of tyrosinase and leads to a decrease in the severity of hyperpigmentation.

For daily UV protection, the patient was advised to use a sunscreen for all skin types with SPF85 Mediscreen SPF85 (Medic Control Peel). The cream has an antioxidant effect and contains chemical and physical filters to protect against ultraviolet rays.

Biorevitalization at A Clinic

At A Clinic, the best and most modern drugs are used for biorevitalization.

Thus, the Swiss drug Profhilo contains ultra-pure hyaluronic acid obtained through a bacterial fermentation process and belongs to the “Highest Quality” class.

The drug is based on hyaluronic acid with low and high molecular weight in equal proportions. This is a special hybrid technology developed and patented by scientists from the world-famous Swiss company IBSA. Low molecular weight hyaluronic acid moisturizes the skin and gives a reinforcing effect. High molecular weight – improves local blood circulation, stimulates the production of your own collagen, and provides tissue lifting. This is achieved due to the accumulation of water molecules around the high molecular weight acid. This formula is called hydrolift.

Profhilo activates the vital activity of not only fibroblasts and keratinocytes, but also adipocytes (fat cells), supports their viability, which leads to the restoration of its own subcutaneous fat, the deficiency of which is determined with age.

High fluidity allows the components of the drug to freely pass through the subcutaneous tissue and dermis, which is not possible with traditional fillers with hyaluronic acid. Profhilo is ideal for introduction into anatomically complex areas - forehead, neck, submandibular areas. Profhilo smoothes out skin defects well, for example, post-acne scars or after chickenpox.

100% pure hyaluronic acid is also contained in the line of products for contouring from Italian and Swiss scientists Neauvia Organic.

This hyaluronic acid is extracted from the bacterium Bacillus Subtilis, which is probiotic and non-pathogenic to humans. The purer the hyaluronic acid, the lower the risk of its rejection by the body. In addition, the scientists who developed the Newvia Organic line of organic fillers decided to use a new cross-linking agent - PEG (polyethylene glycol) polymer. It is widely known and has long been used in the pharmaceutical and medical markets, is non-toxic, and completely decomposes in tissues. PEG helps the filler stay in the skin for a long time. Does not cause adverse reactions. It is PEG that makes the Newvia Organic line of drugs the most biocompatible with the human body. Their tissue rejection is reduced to almost zero. PEG reduces inflammation and granuloma formation.

At certain temperatures that can be reached during procedures in aesthetic hardware cosmetology, such as exposure to laser, ultrasound, and others, traditional hyaluronic acid filler begins to break down. But not Nyuvia fillers. PEG makes the acid much more resistant to heat without limiting the range of aesthetic treatments.

Newvia fillers also have amazing elasticity and plasticity. That is, the ability to change shape and size under the influence of external loads and maintain them or return to their original position. Therefore, each filler in the line adapts to the patient’s existing anatomical structures and at the same time maintains the required shape for long-term aesthetic correction. Nuvia fillers are able to create the desired volume without causing compression of surrounding tissue, thus always providing natural-looking results.

In addition to hyaluronic acid, Newvia Organic contains calcium hydroxyapatite. This naturally occurring mineral triggers the formation of new collagen in the skin. As a result, the density, firmness and elasticity of the skin improves, acquiring the ideal double effect of volume and hydration.

The peptide drug Aquashine is capable of slowing down the aging of the dermis at the cellular level.

Peptides are organic substances that regulate the condition of cells. When introduced into the body, they force cells to work correctly. The effect of restoration of the affected organ or tissue occurs due to the normalization of work at the cellular level. Aquashine preparations contain several peptides. For example, Acetyl Decapeptide-3 activates the production of fibroblasts. Oligopeptide-24 improves skin regeneration, increases collagen production, improves tone, and reduces scars. Oligopeptide-34 stops the aging process, fills skin cells with energy, and reduces the appearance of pigmentation. Oligopeptide-72 prevents the formation of wrinkles and smoothes the skin. Oligopeptide-23 improves metabolism. Oligopeptide-51 shrinks pores and stimulates the formation of elastin.

In addition to peptides, the line’s preparations contain hyaluronic acid, vitamins, including 9 representatives of group B, vitamins C, A, E, K and I (inositol), 24 amino acids, coenzymes, nucleic acids, and minerals.

Hyaluronic acid is contained in Aquashine preparations in two forms - high molecular weight and low molecular weight. At the same time, high molecular weight acid helps transport peptides into the layers of the skin and their accumulation, while low molecular weight acid quickly saturates the skin with moisture and serves as a “transport” for other components.

Vitamins nourish and restore cells, amino acids supply building material for fibroblasts - cells that synthesize collagen and elastin. Coenzymes transport nutrients to cells and activate their defense and division. Nucleic acids are needed to update DNA, and minerals are needed to improve metabolic processes.

The drug from the American company Allergan Juvederm is already a golden classic of hyaluronic skin rejuvenation.

It is suitable for biorevitalization of the face, neck, décolleté and hands. In addition to moisturizing, Juvederm has a healing, restorative, and anti-inflammatory effect. Contains the antioxidant mannitol, which enhances the effect of hyaluronic acid up to three times. The special formula provides effective prevention of skin aging and eliminates signs of aging, tightens the skin well, and restores its turgor. At the same time, Juvederm injections eliminate peeling, enlarged pores, age spots, uneven color, fine wrinkles, and scars.

Thanks to Juvederm, dull, dull skin with signs of sagging and fatigue becomes fresh, radiant and youthful again.

The American biofiller based on hyaluronic acid Restylane can also be called a classic of the genre.

Restylane is especially effective in correcting wrinkles in the forehead, at the outer corner of the eye, on the bridge of the nose and in the nasolabial folds. The drug is also used to correct the shape of the lips. Several effects are achieved here. Firstly, the drug smoothes the skin of the lips, removing small wrinkles that appear with age. Secondly, it corrects the shape of the lips. Thirdly, it is able to increase their volume. Due to Restylane injections, lips not only become fuller, but also acquire a clear contour.

Restylane does not have any adverse effects on the skin, and therefore is often used by patients as a preventative against the appearance of fine wrinkles already at the age of 25-30.

Dermal filler from the German company Merz Pharma Belotero consists of hyaluronic acid molecules stitched together into a mesh polymer, which increases its ability to retain more moisture and start skin renewal processes many times faster.

The drug is ideal for patients with very sensitive skin. A unique feature of Belotero is that, due to its dense structure, it is able to model the contours of the face and neck, removing gravitational ptosis, that is, drooping of facial tissues, and smoothing out neck wrinkles.

Fillers from the Belotero line, in particular, perfectly correct the areas of the cheeks, chin, area around the eyes or forehead, ideal for increasing volume or changing the shape of the lips.

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