Biorevitalization of the face: what kind of procedure is it, the after effect and contraindications

From this article you will learn:

  • biorevitalization: what kind of procedure is it, reviews,
  • photos of patients before and after,
  • injection and non-injection techniques,
  • how much does biorevitalization cost - price for 1 procedure (for 2022).

Facial biorevitalization is a procedure for intradermal injection of high concentrations of active substances, which can significantly improve the appearance of the skin, increase its elasticity, as well as achieve a lifting effect and reduce the depth of wrinkles. Most often, hyaluronic acid, vitamins, microelements, amino acids are used for this, and in older age - components for intensive skin lifting, for example, peptides, DNA-RNA complexes and DMAE.

The composition of the drug is selected individually for each patient. The age of the patient, the condition of the facial skin, and, what is very important, the type of skin aging are taken into account. For example, for fine-wrinkle and deformation types of aging, completely different drugs will be indicated. An important problem is the training of specialists. How often, for example, do mesotherapists tell patients that capillary mesotherapy must be done before administering biorevitalizants? But in many cases, the severity and duration of the biorevitalization effect will depend on this.

Biorevitalization: photo of the procedure

Indications for biorevitalization –

  • therapy for biological skin aging,
  • photoaging therapy (including hyperpigmentation and rosacea),
  • prevention of aging,
  • wrinkles, thinning, decreased elasticity, dry skin,
  • deterioration of the skin as a result of smoking (including the appearance of small vertical wrinkles on the lips).

Thus, the biorevitalization technique will allow you to improve the color and texture of the skin (especially for smokers), increase its elasticity, reduce the depth of wrinkles, and achieve a skin lifting effect. Additional effects of this procedure may include correction of hyperpigmentation, reduction in the severity of rosacea, as well as inflammatory elements of acne. The severity of a particular effect will directly depend on the composition of the chosen drug.

Biorevitalization (revitalization) of the face - what is it?

The development of this method was a real breakthrough in the field of cosmetology. Already after the first session, dramatic changes for the better are noticeable. The essence of the procedure is the introduction of hyaluronic acid-based products into various areas of the dermis. In addition to it, the composition may also contain other biologically active components.

What explains the effectiveness of the method

The condition of the skin is largely determined by the activity of special cells - fibroblasts. Their main function is to produce structural protein components (elastin and collagen). They form an elastic frame that supports all layers of skin tissue.

The effect of biorevitalization of the skin of the face and neck depends on hyaluron. The branched structure of the molecule helps to retain a large amount of water, thanks to which turgor (elasticity) is maintained, which serves to prevent the formation of wrinkles.

Improvement occurs after the first session and consists of:

  • Normalization of moisture levels.
  • Activation of the production of scaffold proteins.
  • Acceleration of regeneration (renewal of cellular composition).

There is also stimulation of the natural synthesis of hyaluron, which significantly enhances and prolongs the rejuvenating properties of the technique.

When is biorevitalization needed?

The procedure can be performed between the ages of 25 and 50 years. The maximum result can be achieved up to forty - the older the patient, the lesser the effect of the drug will be. This is due to the depletion of resources for the synthesis of elastic proteins and a decrease in the number of fibroblasts. To compensate for them, you will need to use additional rejuvenation products.

Let's consider the indications for when facial biorevitalization can be done:

  • To compensate for natural dry skin or caused by harmful factors (smoking, ultraviolet rays, negative temperatures).
  • With pronounced pigmentation. It may occur as a result of congenital characteristics, exposure to sunlight, or metabolic disorders.
  • With age-related skin changes.
  • To correct puffiness and drooping eyelids.
  • For spider veins on the face and neck. Usually the reasons for their appearance are disturbances in blood circulation and vascular tone.
  • For recovery after plastic surgery, laser resurfacing.

What effect will be achieved after biorevitalization depends solely on the cause of cosmetic problems. For example, tissue injury, excessive work of the sebaceous glands, and other skin disorders are successfully eliminated with the help of revitalization. If acne appears as a result of hormonal imbalance, and dull complexion is the result of metabolic disorders, then the benefits of the procedure will be much lower.

Super thin injection needles Nanoneedle

Kurasen dermal biocorrector

Nanoneedles with ultra-thin walls 30G

Nanoneedles with ultra-thin walls 33G

Nanoneedles with ultra-thin walls 34G

Biorevitalization with hyaluronic acid: rationale for effectiveness

Age, ultraviolet radiation, smoking and some other factors lead to gradual aging of the skin. All this leads to a gradual decrease in the activity of fibroblasts and the content of hyaluronic acid (HA) in the skin. A decrease in the activity of fibroblasts leads to a decrease in the production of collagen and elastin, which allows the skin to be firm and elastic, and due to a decrease in the level of HA in the skin, its hydration decreases. As a result, the skin becomes drier and thinner, less elastic, and wrinkles appear.

According to the developers of the biorevitalization method, facial skin rejuvenation occurs by stimulating the activity of fibroblasts that produce collagen and elastin. In addition, the skin’s production of its own HA, which allows it to be more hydrated, also depends on the activity of fibroblasts. For example, if at the age of up to 25 years fibroblasts work at 100%, then in people 25-35 years old their number and activity decrease to 75%, and at 35-45 years old - to 50%, and after 50 years or after menopause in at any age - their number and activity are no more than 25% (compared to young people).

Preparations with low molecular weight HA tend to stimulate angiogenesis and fibroblast function, but at the same time they do not moisturize the skin quite well, because Small HA chains are not able to hold many water molecules (24stoma.ru). But high-molecular HA does not stimulate anything, but retains water well, thereby perfectly moisturizing the skin. Biorevitalizants with HA are indicated primarily for patients with finely wrinkled and tired types of aging, but their use in patients with deformational (edematous) type of aging will only lead to increased swelling and gravitational ptosis of soft tissues.

It is worth saying that now mesopreparations and biorevitalizants with hyaluronic acid are used in most cases by specialists thoughtlessly, because It is believed that the larger the HA, the better. But that's not true. The fact is that when carrying out frequent injections with HA, the latter not only stimulates the activity of fibroblasts or increases skin hydration. Frequent use leads to the activation of enzymes: 1) hyaluronidase - an enzyme that destroys endogenous hyaluronic acid produced by fibroblasts, 2) metalloproteinases - enzymes that destroy the intercellular matrix. Therefore, in fact, you should not do injections with HA more than once a month, and it is better to alternate them with other groups of drugs.

Advantages of the method

The main advantages of this method of rejuvenation include:

  • The ability to correct the oval of the face, smooth out fine wrinkles, and activate the process of cell renewal.
  • No need for lengthy preparation.
  • The total duration is less than an hour.
  • Minimal discomfort.
  • Preservation of the result for a long time (subject to the doctor’s recommendations).

Facial biorevitalization also has disadvantages and contraindications:

  • allergy to the components of the drug;
  • presence of neoplasms;
  • severe chronic and autoimmune diseases;
  • diabetes mellitus in the last stages;
  • active phase of the inflammatory process.

Relative ones include pregnancy, the period of breastfeeding, and the use of anticoagulants.

Kinds

Hyaluronic acid can be administered in different ways. Depending on the method of administration, the cost and other features will differ. The simplest type of revitalization is injection. The degree of injury is minimal and affects only the superficial layers.

Injection biorevitalization

Revitalization is carried out under sterile conditions using modern proven drugs. The injection is administered deep into the dermis using a syringe equipped with a thin needle. Most often, a point technique is used (punctures follow each other at a distance of up to 1.5 cm).

Since the procedure is traumatic, it is performed in combination with local anesthesia. Together with a cosmetologist, it is important to choose in advance the correct method of how to do facial biorevitalization in order to eliminate contraindications and choose the best option. There are two main ones:

  1. Manual. The specialist personally performs the injections, thereby reducing the amount of damage.
  2. Hardware. The substance is administered with a special device. It has a more aggressive effect, the cosmetic product is distributed as evenly as possible.

Recovery takes 1-3 days, after this period the effect becomes clearly visible.

Non-injection biorevitalization

In this case, hyaluronic acid is introduced using auxiliary technologies. The risk of complications is minimal and no recovery is required after the session. The technique is divided into several varieties:

  • Cryo-biorevitalization. Involves the use of liquid nitrogen.
  • Ultraphonophoresis. The drug enters the skin under the influence of ultrasound.
  • Iontophoresis. The substance penetrates the dermis due to galvanic current. It also stimulates metabolic processes and regeneration.
  • Magnetophoresis. Hyaluronic acid is injected using magnetic waves.

Any of these options can be used if there are certain contraindications or for clients who are afraid of injections.

Laser biorevitalization

It is placed in a special category, since in addition to the drug, the laser radiation itself also has an effect. Due to this, it is possible to obtain the following results:

  1. Improving microcirculation of blood and lymph. This provides an additional flow of oxygen and nutrients.
  2. Reducing inflammation.
  3. Increased production of scaffold proteins.
  4. Correction of uneven microrelief and microscars from acne.

Using a laser, cosmetologists introduce low molecular weight varieties of hyaluronic acid. It penetrates the skin better and has an increased stimulating effect on fibroblasts.

Injection biorevitalization of the face

The technique can be divided into three stages. Before using it, you should definitely consult a specialist to exclude contraindications. For example, the technique cannot be used during pregnancy or in the presence of acute inflammatory diseases.

All stages take about 30-40 minutes, in some cases up to 1 hour. Moreover, most of the time (15-20 minutes) is spent waiting for the anesthetic to take effect. The injections themselves are performed in 10-15 minutes.

Preparation for the procedure

During the consultation process, cosmetologists conduct an external examination of the skin and interview the patient. Then the area of ​​influence, the optimal drug, and the method of its administration are selected. CURACEN has proven itself well - it is a multi-component product that has a complex restorative effect - reducing the rate of skin aging, preventing the appearance of wrinkles, preventing and treating pigmentation.

Progress of the procedure

Before visiting a specialist, you should avoid stress and alcohol consumption, and also not smoke a couple of hours before the session. Before biorevitalization and before injecting the substance, cosmetologists follow the following algorithm:

  • Removing makeup from the client's face.
  • Treat the skin with an antiseptic solution and mark the area where the composition is introduced.
  • Application of local anesthetic.
  • Injections of the drug are performed using Japanese NANONEEDLE needles. They make the procedure less painful and traumatic. This means that the rehabilitation period will go faster.

For women, it is advisable to carry out manipulations after the 14th day of the menstrual cycle. This is due to increased pain sensitivity and significant hormonal changes that are observed in most clients before this time.

Consolidate the result

After the end of the session, medicinal cosmetics with a soothing and anti-inflammatory effect are applied to the skin, and in the summer, cream with SPF. Next, the cosmetologist evaluates the patient’s condition and makes recommendations for further home care.

Biorevitalization of the face: reviews from doctors and patients

Over the past 10 years, the composition of drugs for mesotherapy and biorevitalization of the face has changed dramatically, and if earlier it was impossible to achieve express lifting, reducing the depth of wrinkles, and increasing collagen production, now this has become a reality. Of course, mono-preparations of hyaluronic acid can already be considered the last century of cosmetology. They are best used primarily in patients with a fine-wrinkled type of aging under the age of 25-30 years, who do not yet require intensive rejuvenation.

For patients with fine-wrinkle type of aging 30+, in addition to hyaluronic acid, vitamins (especially vitamin C), B vitamins, antioxidants that protect against photoaging, amino acids proline, glycine and lysine are very important to stimulate collagen production, cysteine ​​is to correct hyperpigmentation. Further 40-45+, peptides, nucleotides, and growth factors that stimulate collagen production are added to the above. Remember that it is better not to use HA more than once a month, i.e. you need to combine and alternate different drugs.

An important point - remember that in patients with deformational (edematous) type of aging, the use of HA, especially its high concentrations, will only aggravate swelling and deformation of the face, and increase gravitational ptosis. In such patients, it is very important to carry out capillary mesotherapy in the amount of 4-5 procedures, and to use preparations with nucleotides, peptides, amino acids, and vitamins as biorevitalizants. The use of GC in such patients is possible only in small concentrations of 0.3-0.5% and only at the final stage of treatment.

Let us say right away that there are very few qualified mesotherapists. Most people just want to quickly inject the patient with 1.0-2.0 ml of biorevitalizant and earn money. Almost no one is engaged in activating lymphatic drainage and blood supply to the skin of the face. That is why many patients have negative reviews of biorevitalization. They say it's expensive and the effect doesn't last long.

Bioreparation and biorevitalization: differences

Recently, in advertising of injection procedures for rejuvenation, the terms “bioreparation” and “biorestructuring” can increasingly be found. It’s just that each manufacturing company is trying to differentiate itself from others, and therefore they introduce new and new terms. Essentially, the term bioreparation means “restoration.” In my opinion, speaking objectively, bioremedies include preparations with nucleotides (DNA-RNA complexes), regulatory peptides and growth factors.

Carrying out

Injections can be performed using several (different) methods; the type is selected by the cosmetologist depending on the area and condition of the skin.

Papular technique

The drug is injected into the middle and superficial layers of the dermis. The needle is placed at an acute angle (about 15 degrees) and held with the cut facing upward. Small elevations form on the surface of the skin - papules, filled with the injected substance, which is gradually distributed in the surrounding tissues. When using products based on synthesized hyaluronic acid, the recovery process can take up to 3 days. When using the drug CURACEN - from 20 to 60 minutes. The consequences of such a cosmetic procedure are positive; biorevitalization is characterized by long-term preservation of the effect due to the slow resorption of the drug.

The average size of the tubercles is about 4 mm. In particularly delicate areas (around the eyes and lips), smaller papules are created, up to 2 mm in diameter.

Tubercular or micropapular technique

Injections are made with a 4 mm long needle at an angle of 45 degrees. Due to this, the active substances penetrate into the deepest layers of the dermis. Externally, the skin remains smooth, only traces of injections are visually visible.

Linear-retrograde technique

The essence of the technique is to introduce the composition with a long needle (up to 13 mm), which, after puncture, is carried parallel to the surface of the skin through the middle layers. On the reverse movement of the syringe, the active substance is injected.

By using this technique, specialists are able to reduce the number of injections, and the deep penetration of the needle additionally stimulates the regenerative processes of the skin. How long the effect of facial biorevitalization in this way will last largely depends on the skill of the cosmetologist, the individual characteristics of the patient and home care. On average, this period ranges from 6 months to 1 year.

Why is capillary mesotherapy needed?

This is a good way to prepare for revitalization and other cosmetic procedures, allowing you to significantly increase microcirculation, accelerate lymph flow, increase blood flow, and reduce swelling. It is prescribed for:

  • Severe sagging skin (ptosis).
  • Severe swelling.
  • Large-scale age-related changes.

For capillary mesotherapy, cosmetologists use vascular preparations. They are introduced first into the cervical-collar region, slowly moving towards the earlobes, collarbones, and submandibular area. Next, injections are made along the tension lines. Usually 1-2 sessions are enough, but their number can increase to 4-5 if problems in this area are severe.

Important: selection of drugs for biorevitalization

In practice, we most often encounter 2 types of skin aging. Firstly, a finely wrinkled type of aging, which appears already by the age of 30, and in the eye area even earlier. This type is characterized by thin, dehydrated skin and a large number of small expression wrinkles, especially in the eye area. For this type of aging, the use of hyaluronic acid (HA) is a priority. And if in young patients 25-30 years old it is still possible to use biorevitalizants containing only HA, then in patients 30-35 years old the biorevitalizant must already contain vitamins, microminerals, amino acids, and antioxidants.

In patients aged 35-40+ years with a fine wrinkled type, the biorevitalizant should preferably contain (in addition to the above components) nucleotides and matrikin peptides. The latter stimulate collagen synthesis. Moreover, after 30-35 years with this type of aging, in order to achieve a good effect, it is desirable to carry out in parallel 2-3 procedures of capillary mesotherapy of the face, neck, collar area with vascular / drainage drugs - to stimulate lymphatic drainage and blood supply to the skin.

But if patients of this type show symptoms of skin photoaging - such as hyperpigmentation and telangiectasia, then additionally vitamin C, antioxidants (glutathione, coenzyme Q10, thioctic acid), cysteine, lightening peptides will be needed. Vitamin C and antioxidants relieve oxidative stress that occurs when exposed to solar radiation. A drug with this composition will also be useful before going on vacation to hot countries.

Deformation type of aging - but the main type of aging of most Russian women is deformation (edematous). Such patients usually have dense skin, fairly few wrinkles, a large volume of soft tissues of the face due to interstitial edema of the subcutaneous fat, and also have pronounced nasolabial folds and jowls. This type of aging develops due to impaired venous outflow in the face and neck, and is provoked primarily by problems with the cervical spine. If such patients are given drugs with GC, this will further increase the swelling of the face and, as a result, gravitational ptosis of the soft tissues.

Therefore, in such patients, capillary mesotherapy (lymphatic drainage vascular injection) takes first place, as well as, according to indications, the use of lipolytics in the area of ​​fat pads of the face and double chin. During the first 2-3 visits, capillary mesotherapy can be carried out as a single procedure, or it can be combined immediately with the introduction of biorevitalizants. The latter, in case of deformation/edema type of aging, should contain DNA-RNA complexes, as well as vitamins (primarily vitamin C), amino acids, and peptides.

Why is “capillary mesotherapy” (vascular injection) needed?

It is impossible to achieve a pronounced biorevitalization effect (primarily with the deformation type of aging) without stimulating the blood supply to the skin and activating lymphatic drainage. This injection is carried out with vascular preparations “Artichoke”, “Gingko Biloba”, “Rutin + melito extract” or “GAG Complex DVL Capyl”. This is especially true for patients with ptosis, rosacea or complaints of facial swelling. In all these groups of patients, lymphatic drainage vascular injection of the face and cervical-collar area should be done at least 4-5 times.

The volume of vascular preparations per procedure should be no more than 5 ml. First, the cervical-collar area is treated, then injections are made in the projection of the lymph nodes - the area of ​​the earlobes, the sternocleidomastoid muscle, in the area of ​​the jugular fossa and clavicles, as well as in the submandibular area. After this, a series of injections are made along the massage lines of the face and the infraorbital area. In patients with a finely wrinkled type of aging, it is advisable to do 1-2 such vascular puncture procedures, but in patients with a deformational type of aging or patients over 45 years old, 5 or more procedures can be safely performed.

The combination of the drainage drug “Artichoke” with the vascular drug “Rutin + melito extract” will normalize venous outflow, activate lymphatic drainage and microcirculation. All this will remove interstitial edema of the subcutaneous fat, which will reduce the volume of soft tissues and the degree of gravitational ptosis, as well as the severity of the folds. If a patient is prescribed a course of several biorevitalization procedures, then each procedure begins first with a vascular puncture and only after that are injections of the biorevitalizant given. Or the first 2-3 procedures are done only by capillary mesotherapy + soft lipolytics on the face, and biorevitalizants are added only from the 4th procedure.

How effective is it?

In the photo above you can see the effect of facial biorevitalization before and after the procedure. It lasts quite a long time, the specific period depends on the condition of the client’s skin, the severity of the problems, heredity, lifestyle and other factors. On average, one session lasts 6-12 months. To improve the results, you can carry out additional manipulations, their number will depend on the goal:

  • Preventive – 1-2 sessions are enough.
  • Medicinal – less than 5 is required.

The interval between them is determined by a specialist, usually the interval is about 1 month. How often biorevitalization is done after the main cycle again depends on the recommendations of a specialist. Usually one procedure is prescribed every six months, this allows you to maintain youthful skin for a long period.

Facial biorevitalization: before and after photos, effect

You will have great difficulty finding real photos before and after biorevitalization, because... Cosmetology clinics post only cases of the most successful procedures, or simply take photographs of patients after hardware rejuvenation techniques, passing them off as biorevitalization procedures. The following 2 photos are from an independent clinical study. Each patient was administered 2.0 ml of Restylane Vital during 1 procedure. The course of treatment consisted of three procedures done with an interval of 4 weeks.

Biorevitalization: before and after photos (course with HA mono-drug)

As you can see: the effect of therapy with a mono-drug of hyaluronic acid in patients aged 35 and 46 years is either minimal or not noticeable at all. As we said above, patients over 30 years old need other drugs containing vitamins, amino acids, microminerals, antioxidants, and 40-45+ also nucleotides, peptides and growth factors. What do you think: will patient reviews for such facial biorevitalization be positive? It is unlikely that cosmetology clinics will post such photographs.

Example No. 2 –

The following photos were taken by cosmetologist Victoria Petrovskaya. The patient underwent a course of 4 procedures, once every 2 weeks. At the beginning of each procedure, lymphatic drainage vascular injection was first performed with the drug “GAG Complex DVL Capyl formula”, then “Hydro Line P-Anti-wrinkles formula” - for the periorbital area, and “Hydro Line Peptide formula” - for all other areas of the face. Photos were taken after the second procedure. Those. Each procedure used the same 3-drug regimen.

Example No. 3 –

The following photos were taken by cosmetologist A.Yu. Voropaeva. The patient underwent a course of 4 procedures, once every 10-14 days. At the beginning of each procedure, lymphatic drainage vascular injection was first performed with the drug “GAG Complex DVL Capyl formula”. Then, different biorevitalizants were used in each procedure -


  1. "Nucleospire Revitalizing Complex A"

  2. "Nucleospire DNA-RNA 2%",
  3. "Nucleospire Revitalizing Complex A"
  4. "Nucleospire DNA-RNA 2%".

Example No. 4 –

The following photos were taken by cosmetologist Irina Pyagai. The patient underwent a course of 8 procedures, once every 10 days. At the beginning of each procedure, lymphatic drainage vascular injection was first performed with the drug “GAG Complex DVL Capyl formula”. Different biorevitalizants were used in different procedures -


  1. "Nucleospire Revitalizing Complex A"

  2. "Nucleospire Revitalizing Complex B formula",
  3. "Nucleospire DNA-RNA 2%",
  4. "Nucleospire Revitalizing Complex B formula",
  5. "Nucleospire DNA-RNA 2%",
  6. 7. 8. procedures – “Nucleospire DNA-RNA 1% DM Peptide formula”.

What you need to know about drugs

The exchange of hyaluron occurs quite quickly; without additional stabilization, it is absorbed in 1-2 days. If you give it a gel-like consistency, it will be possible to form a depot in the tissues, which will significantly prolong its resorption. To further increase the period of exposure, the substance is subjected to chemical stabilization, which significantly lengthens the decomposition time.

What facial biorevitalization gives depends on the type of drug used in cosmetology. There are two of them:

  1. Low molecular weight. It retains less water, but small molecules act as signals, stimulating the work of fibroblasts and accelerating the natural regeneration of the skin. Significantly improves the overall condition of the skin and has an increased anti-aging effect.
  2. High molecular weight. Provides a high degree of moisture retention, significantly increases turgor, and promotes rapid smoothing of shallow wrinkles.

Depending on the composition of the drugs, they are divided into:

  • Monocomponent. Contains one active ingredient (hyaluron). Inexpensive, well suited for slowing down age-related changes under the age of 35, in the absence of other health problems. Allows you to normalize the level of moisture in tissues and eliminate fine wrinkles.
  • Combined. They contain vitamins, microelements, and other useful compounds. Well suited for women 35-45 years old who do not have serious skin health problems. The drugs eliminate pigmentation and reduce the degree of photoaging.
  • Powerful biorevitalizants. They contain many active components, such as peptides, various growth factors, amino acids.

Among the drugs is CURACEN from the Japanese manufacturer Japan Bio Products. It allows you to significantly reduce the rate of cellular aging, compact and even out the surface layers of the epidermis. This is achieved by enhancing the synthesis of its own structural proteins, such as collagen and elastin.

When choosing a suitable product, be sure to consult a cosmetologist. Cosmetologist specialists can correctly assess the condition of your body, indicate indications and choose the most effective and safe product.

Anti-age drugs

Bb Laboratories – Hyaluron-elastin-collagen extract

Laennec – solution for injection

Curacen Essence (20 fl x 2 ml)

Two-phase placental serum concentrate

Biorevitalization – which drugs are better?

Hyaluronic acid is included in both preparations for biorevitalization and fillers - preparations for contouring. This is one of the main ingredients in creams, skin serums, and the basis of rejuvenation products. What preparations of unstabilized hyaluronic acid exist that are used for biorevitalization and bioreparation? Which ones have proven to be effective and safe? Let's consider the main preparations of hyaluronic acid for the face, registered in Russia, approved for use and time-tested.

What are the main hyaluronic acid preparations that have proven themselves well in the cosmetic services market?

Preparations for biorevitalization containing only hyaluronic acid

IAL-SYSTEM, Ial-system (made in Italy). Contains unstabilized hyaluronic acid at a dose of 18 mg/g. At this point in time, it is the leader among modern drugs for biorevitalization, the “gold standard”. Ial System is an effective, reliable, high-quality biorevitalizant for combating dehydrated skin.

Clinical effectiveness: skin hydration.

Indications for use: recommended for patients of any age and any skin type, especially dry and thin.

Features: marks from injections disappear quickly, after 4-5 hours or the first day.

Basic course: 5 procedures with an interval of 14 days.

IAL-SYSTEM ACP (Italy). Contains partially stabilized hyaluronic acid (HA) at a dose of 20 mg/g, that is, the density of HA in this preparation is greater, therefore, it is contained in the dermis longer and acts for a longer time. Most often, IAL System ACP is used after 3 facial biorevitalization procedures with IAL System to enhance the effect. It is also possible to combine these two drugs for injection into different areas.

Clinical effectiveness: moisturizes, creates a “depot” of hyaluronic acid in the skin to maintain tone and prevent the formation of wrinkles.

Recommendations for use: recommended for patients of any age and any skin type, especially thick and severely dehydrated.

Features: papules last longer than after injections of other drugs.

Basic course: 3 procedures once a month

Teosyal Meso, "Teosyal Meso" (manufacturer Switzerland). The main active ingredient is unstabilized hyaluronic acid at a dose of 15 mg/g. Its molecular weight in Teosyal Meso is 1 million Da, which leads to ideal absorption in the dermis.

Clinical effectiveness: moisturizing, improving skin tone, preventing aging.

Indications for use by age and skin type: thin skin, including young skin, due to its low density, can be used for the skin around the eyes in patients prone to swelling.

Basic course: 4 procedures every 2-3 weeks.

Viscoderm "Viscoderm" (produced in Italy). Also contains hyaluronic acid in concentrations of 8 mg/g, 16 mg/g or 20 mg/g. The higher the content of hyaluronic acid in the syringe, the longer the papules persist after the procedure.

Clinical effectiveness: prevents the formation of wrinkles, smoothes fine wrinkles, improves the tone and color of the skin.

Recommendations for age and skin type: Viscoderm 0.8% is designed for young and middle age; 1.6% - for thin skin 30-40 years old, 2.0% - for correcting age-related skin changes after 40 years. But do not forget that biological age does not determine the choice of drug; it depends on the condition of the facial skin and the desired effect in the patient.

Features: The higher the percentage of hyaluronic acid, the longer the papules last (from several hours to several days)

Basic course: 4 procedures once every 2-4 weeks (depending on concentration)

Princess Rich – Princess Rich (made in Austria). A preparation based on hyaluronic acid at a concentration of 18 mg/g

Clinical effectiveness: activates collagen production in tissues, improves tone, retains moisture

Recommendations by age and skin type: suitable for all skin types

Basic course: 3 procedures once a month

The preparations described above contain only hyaluronic acid. Preparations of “pure” hyaluronic acid can be used from the age of 18 to improve tone, protect against ultraviolet radiation and premature aging.

Preparations for biorevitalization and bioreparation containing hyluuronic acid and additional ingredients.

Hyalrepair, “Hialrepair” (made in Russia) - contains unstabilized hyaluronic acid at a dose of 14 mg/g or 2 mg/ml, as well as vitamins + amino acids.

The effect of injections: smoothing the relief of superficial wrinkles, improving skin color and texture, increasing skin turgor, and has a lifting effect.

Recommendations by age and skin type: for middle and older age.

Features: the group of drugs “Gialripayer” includes several types that differ in indications and composition.

Basic course: 3 sessions every 3 weeks.

Meso-Wharton P199, “Meso-Wharton” (produced in the USA). A biological agent based on unstabilized hyaluronic acid at a dose of 15 mg/g + a peptide isolated from the umbilical cord and artificially synthesized, regulating the activity of stem cells by stimulating the release of growth factors. + complex of vitamins, coenzymes, antioxidants and growth factors.

The result of the procedure: fights age-related changes, improves cellular renewal, tightens contours, smoothes folds and wrinkles.

Recommendations for use: recommended for patients over 40 years of age.

Basic course: from 4 to 8 injections with an interval of 1 week, followed by monthly maintenance therapy.

Features of the period after the procedure: redness and swelling are possible 2-3 days after the procedure.

Meso-Xanthin F199 “Meso-Xanthin” (USA manufacturer). The drug contains hyaluronic acid + Fucoxanthin (derived from seaweed and maintains the stability of the DNA chain under various external and internal stresses) + Growth factors + peptides + amino acids + vitamins + nucleic acids

Clinical effectiveness: has a restorative effect not only at the cellular, but also at the gene level. After a course of procedures, wrinkles are smoothed out, skin elasticity and tone improve, pigment spots disappear, the severity of vascular patterns decreases, and a noticeable lifting effect.

Age recommendations: after 25 years

Main course: 4-6 sessions every 1-2 weeks

Jalupro, "Jalupro" (made in Italy) is a drug containing hyaluronic acid 1% or 2% + amino acids (lysine, proline, glycine, leucine).

The result of the procedures: effective in the presence of small and medium-sized expression and age wrinkles, post-acne and stretch marks, pigmentation and dry skin.

Recommendations for age and skin type: after 35 years.

Main course: 4-5 sessions at intervals of once a week.

NCTF 135, or NSTF 135 (made in France, Filorga). Also a drug that includes unstabilized hyaluronic acid + 12 vitamins + 20 amino acids + 6 minerals + 6 coenzymes + 5 nucleic acids + 2 antioxidants.

Clinical effectiveness: moisturizes, improves tone, elasticity, has antioxidant properties, fights post-acne

Recommendations for age and skin type: there are three drugs, which are conventionally divided according to the patient’s age:

“Innovative cocktail” NCTF 135+ for persons under 30 years old,

"Enriched" NCTF 135 HA for ages 30 to 35

“Extra-enriched” NCTF 135 HA+ for skin over 35 years old.

Main course: 4-6 sessions once every 1-3 weeks, depending on the composition of the cocktail.

JUVEDERM Hydrate , "Juvederm Hydrate" (made in the USA) is a preparation based on hyaluronic acid at a concentration of 13.5 mg/g with the antioxidant mannitol. This combination of the drug provides the greatest reinforcing effect. Mannitol shields cells from free radicals and prevents the breakdown of hyaluronic acid, thereby prolonging the effect of skin hydration and rejuvenation.

Result: moisturizes and increases skin elasticity, lifting effect

Recommendations for age and skin type: any skin of any age.

Basic course: once every 3-4 weeks, 4 procedures

It is worth remembering that it is better to focus your energy on preventing skin aging than correcting its manifestations. Based on the needs of the skin and lifestyle, the cosmetologist will select an effective drug and recommend a course of injections.

Complications and precautions

Side effects for this technique are uncharacteristic and are observed extremely rarely. They usually appear as:

  • Allergies to anesthesia or drug components.
  • Microhematoma. The number of subcutaneous hemorrhages depends on the characteristics of the skin, the condition of the capillaries and microarteries.

There are also cases of infection penetrating into the dermis. Such situations arise when aseptic rules are not observed during the procedure or subsequent care is improper. If all standards and recommendations are followed, the likelihood of infection is zero. A consultation with a specialist dermatologist will help you decide whether biorevitalization is worth doing.

Avoiding negative consequences is quite easy. To do this, strictly follow medical recommendations, including:

  • Do not touch your face for 24 hours after the session.
  • Do not wear makeup for 48 hours.
  • Avoid physical and mental stress, stress for 2 weeks, avoid going to the bathhouse or public swimming pools.
  • Avoid drinking alcohol.

When washing, you need to use gentle cleansers that do not dry out the skin. It is also necessary to use an antiseptic recommended by a doctor, regularly treating the dermis until the injection marks are completely healed, and drink the recommended amount of water.

Now you know the basic information about facial biorevitalization and understand that this procedure helps get rid of wrinkles, significantly slowing down age-related changes in the skin. To avoid negative consequences, it is important to use certified drugs. Entrust the care of your health to specialists.

Benefits of biorevitalization

  • painlessness;
  • high efficiency of rejuvenation;
  • prolonged result;
  • affordable price;
  • minimum list of restrictions;
  • complications are kept to a minimum.

Do you want to look 18 at 30-35 years old? Then it’s time to start investing in your beauty so that by the age of 50 you don’t get depressed from the number of moisturizers on the shelf and aging skin.

in St. Petersburg will return youth to your hands. We use only certified and safe drugs, we achieve excellent correction results at an affordable cost of services, as evidenced by numerous reviews from our clients.

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