special instructions
Wait at least 1 hour before using any other anti-acne medication for external use.
If your acne does not improve within 3 to 4 weeks, you should consult your doctor (it may take 2 to 3 months to achieve the full therapeutic effect).
With prolonged use, superinfection may develop.
During the treatment period, it is possible to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
pharmachologic effect
Erythromycin included in the drug is a macrolide antibiotic. This is what determines the bacteriostatic effect of the drug. In addition, it is capable of exerting a bactericidal effect on a wide group of gram-positive organisms.
At the same time, most gram-negative bacteria, mycobacteria, viruses, and fungi are resistant to the drug.
Erythromycin is much better tolerated than penicillins, so it is prescribed for allergic reactions to the latter.
Zinc acne ointment
Zinc ointment contains zinc oxide and petroleum jelly as an auxiliary component. Zinc is an important trace element in the human body; it stimulates the activity of enzymes and is involved in the synthesis of hormones in the body, including the main male sex hormone testosterone. Its deficiency in the body can cause skin diseases, in particular acne.
From my own experience, I have learned that zinc ointment significantly reduces sebum production, dries out acne, reduces skin irritation, and relieves inflammation. Effectively used in the form of an ointment as an external remedy for acne, and in the form of tablets (the drug Zincteral).
It is necessary to apply zinc ointment pointwise to problem areas, slightly rubbing the ointment into the skin of the face. I do this procedure before bed.
Side effects
When treated with Erythromycin ointment, the following side effects may develop:
- irritant effect causing itching, redness;
- other allergic manifestations ;
- disorders of the digestive system: vomiting, nausea, diarrhea, dysbacteriosis, etc.;
- candidiasis;
- tinnitus and hearing loss;
- tachycardia.
With prolonged treatment, it is possible to develop a secondary infection, which was provoked by microorganisms resistant to erythromycin .
Erythromycin and adenoids
Erythromycin nasal ointment is prescribed for the treatment of adenoids in the initial stage . It is effective when enlarged adenoids are accompanied by inflammation of the sinus mucosa (runny nose). In this case, the antibiotic acts on the source of the infection and treats the inflammation.
If the cause of the enlargement of the adenoids is the proliferation of lymphoid tissue without the presence of an infectious agent, then the use of antibacterial ointment will be ineffective.
Using ointment during pregnancy
Erythromycin ointment during pregnancy is used only as prescribed by a doctor . It is important to understand that this antibiotic crosses the placenta and enters breast milk. Therefore, the prescription and use of this drug must be competent.
This remedy should not be used in the first half of pregnancy (local use of a bacteriostatic substance can pass it into the general bloodstream and through the placenta). Due to the fact that there are no systemic studies and sufficient data on the effect of erythromycin on the fetus, the drug is used with great caution. Even in the second half of pregnancy, erythromycin ointment is prescribed only in cases of urgent need, when it is impossible to do without this remedy.
Note: in medical terminology the phrase is often used that a drug can be used if the risk from the consequences of infection is higher than the risk from complications of treatment with this drug.” This phrase applies to any bacterial preparations, including erythromycin ointment. Erythromycin ointment is an antibiotic, and its use should be balanced, competent and meaningful.
Children and erythromycin
Erythromycin ointment for children is approved for treatment from the first days of life (if indicated and necessary). Erythromycin ointment is prescribed for infants to treat skin and eye inflammation. It is used in the treatment of birth infections when the baby is infected while passing through the birth canal. Often, an infection of the birth canal spreads to the skin of the face and mucous membranes of the eyes (causes conjunctivitis)
. For its treatment, erythromycin ointment is prescribed.
Note: external treatment with erythromycin for newborns is prescribed if there is no severe jaundice.
Erythromycin ointment for acne
Erythromycin ointment helps get rid of acne due to its composition containing the antibiotic Erythromycin, which is used for both external and internal therapy.
Erythromycin copes well with ulcers that are caused by infectious microorganisms. It has an anti-inflammatory and antibacterial effect, destroys skin infection pathogens. In my opinion, erythromycin ointment is an excellent home remedy for acne.
The composition of the well-known Zinerit, which is advertised on almost every website about problem skin, includes zinc and erythromycin - the two main active components of the drug.
I don’t understand why overpay for Zinerit if you can mix its main components in the form of zinc and erythromycin ointment yourself.
In other words, to prepare “Homemade Zenerite”, squeeze out a little erythromycin and zinc ointment from the tube, mix (I do all the manipulations directly on the palm of your hand) and apply directly to the pimples. It is better to do it in the evening to leave the ointment on your face overnight.
You can also use Erythromycin in tablet form. Grind the Erythromycin tablet into powder, mix with zinc ointment and apply pointwise to acne. This option is more effective and I like it better.
All antibiotics for acne: external and internal
Interaction
If Erythromycin is used simultaneously with Aminophylline , caffeine , Theophylline , then the plasma concentration of the latter increases. As a result, the risk of toxic effects increases.
Erythromycin increases the concentration of cyclosporine in the blood, thereby increasing the likelihood of nephrotoxicity.
Agents that block tubular secretion increase the half-life of erythromycin.
Antibiotics of the erythromycin series are not compatible with Clindamycin , Lincomycin , Chloramphenicol . Under the influence of erythromycin, the bactericidal effect of beta-lactam antibiotics .
Simultaneous treatment with Erythromycin and Theophylline increases the level of the latter.
If concomitant treatment with erythromycin and drugs that are metabolized in the liver is carried out, the concentration of these drugs in the blood plasma may increase.
Erythromycin reduces the effectiveness of hormonal contraceptives .
The simultaneous use of Erythromycin ointment and abrasive substances that irritate the skin or provide exfoliation leads to a drying irritant effect.
Analogs
Level 4 ATC code matches:
Zinerite
Dalatsin
Zerkalin
Klindovit
Erythromycin
Analogs of Erythromycin ointment are Tetracycline ointment , drugs Ciplox , Dex-Gentamicin , Tobradex .
Indications for use
Erythromycin ointment is used to treat infectious and inflammatory diseases caused by microorganisms sensitive to erythromycin. It is used in the treatment of infectious and inflammatory diseases that were provoked by pathogens that exhibit resistance to tetracyclines , chloramphenicol , penicillin , streptomycin .
Externally used to treat juvenile acne .
Local use of drugs is indicated for infectious and inflammatory eye diseases.
Erythromycin ointment is also prescribed for the treatment of trachoma, inflammatory processes of the mucous membrane of the eyes, for the treatment of pustular diseases of the skin, bedsores of infected wounds, burns, trophic ulcers.
Erythromycin skin and eye ointment
Erythromycin ointment is produced by many pharmaceutical companies. It has two external forms - ointment for the skin and ointment for the eyes. Both forms contain the same concentration of the active substance (in 1 g of ointment - 10,000 units of antibiotic
).
They differ in their base - the ointment contains petroleum jelly, and the eye gel contains lanolin and sodium disulfite.
Therefore, the eye ointment has a light yellow tint, and the skin ointment has a brown-yellow color. Skin ointment - used to treat various inflammations of the skin and subcutaneous soft tissues. Ophthalmic – for inflammation of the eye tissues. For a more detailed description of the list of inflammations for which skin and eye ointments are used, look at the instructions for these two drugs.
Skin ointment
Instructions for use of erythromycin ointment regulate its use for various infections of the skin and soft tissues. For pustules and acne, for the treatment of infected bedsores, burns and frostbite, for any damage to the skin with subsequent infection. For effective treatment, it is important to understand that erythromycin is used when the wound is inflamed and has suppuration .
If the wound is not infected, if there is no pus, then there is no need to use an antibiotic. To speed up healing, you can get by with a regenerating composition (panthenol spray, solcoseryl gel, sea buckthorn oil)
.
And to prevent infection, treat the wound with antiseptic solutions (peroxide, brilliant green, Castellani paint, iodine)
.
External erythromycin ointment is applied to inflamed areas of the skin 2-3 times a day for one to two months.
It is important to know that long-term use of erythromycin ointment (like any other composition with an antibiotic) leads to addiction . Pathogenic bacteria adapt to the action of erythromycin and continue to multiply in its presence.
Vivid examples of the development of resistance (stability) are the following facts. According to Japanese statistics, 60% of pneumococcal strains are resistant to erythromycin. In Finland, resistance to this antibiotic was detected in 45% of streptococcal strains. The tendency to increase the resistance of pathogenic microorganisms increases after the active administration of erythromycin to children.
special instructions
Avoid contact of the drug with mucous membranes and sensitive areas of the skin (eyelids, neck, supraclavicular cavity).
The use of another anti-acne drug for external use is possible no earlier than an hour later.
If generalized urticaria appears, treatment should be discontinued and systemic corticosteroids should be prescribed.
After each use of the drug, you should wash your hands thoroughly.
If infection occurs, the drug should be discontinued and appropriate therapy should be prescribed.
When using the drug, it is possible to develop cross-resistance to other macrolide antibiotics, lincomycin, clindamycin.
Propionibacterium strains are becoming more resistant to antibiotics. To prevent the development of resistance during treatment with Erythromycin in the form of an ointment for external use, the patient should not use other oral antibiotics. The patient should not use the drug for a longer time than necessary, however, treatment should continue for at least 6 months.
Pediatric use: The safety and effectiveness of erythromycin ointment in pediatrics has not been established.
Overdose
Accidental overdose is unlikely due to the nature of the topical use of the drug.
Drug interactions
When erythromycin is used simultaneously with drugs that cause desquamation of the epidermis (for example, benzoyl peroxide, tretinoin, resorcinol, salicylic acid, sulfur), side effects may increase.
Concomitant use of another local antibacterial drug is contraindicated.
Erythromycin should not be used simultaneously with drugs that cause skin desquamation, as well as with cosmetic and hygiene products that cause dryness and irritation of the skin.
Erythromycin should not be used concomitantly with clindamycin because they competitively bind to the 50S ribosomal subunit.
Release form
1% ointment for external use in aluminum tubes of 20 and 25 g along with an insert in a cardboard pack.
Best before date
3 years. Do not use after expiration date.
Storage conditions
Store out of reach of children, in a dry, dark place at a temperature not exceeding 150C.
Vacation conditions
Dispensed with a doctor's prescription.
