Which is better: “Baziron AS” or “Skinoren”?

Acne is a big problem for many people. Unpleasant skin rashes cause not only aesthetic discomfort, but sometimes even serious pain.

A sick person is faced with the problem of choosing a medicine. Various antiseptic drugs are often prescribed.

Which is better – Baziron or Skinoren among the prescribed drugs?

Comparison of the effectiveness of Baziron AS and Skinoren

The effectiveness of Baziron AS is quite similar to Skinoren - this means that the ability of the drug substance to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Baziron AS is more pronounced, then using Skinoren even in large doses will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Baziron AS and Skinoren. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Features of the first medicine

Baziron AS is the trade name of the drug, invented by the manufacturer. The medicine is based on one active ingredient – benzoyl peroxide.

This component exhibits antimicrobial activity against the most common acne-causing bacteria - propionibacteria and Staphylococcus epidermidis.

In addition to destroying the pathogen, the medicine has the following effects:

softens the skin,
removes keratinized scales,
enriches nearby tissues with oxygen,
improves blood flow in the acne area,
suppresses the activity of the sebaceous glands.

After application to the skin, the medicine is slightly absorbed , entering the circulatory system. However, in the body the active substance of the drug is metabolized into safe benzoic acid.

It is completely eliminated through the kidneys. The medicine does not accumulate in tissues, does not create dangerous concentrations, and it is impossible to overdose .

How is Baziron AS used?

The medicine is applied to the affected areas in a thin, even layer twice a day. The skin must be dry. In the presence of moisture, the effect of the drug is greatly reduced.

The minimum course of therapy is 1 month. The average duration of treatment is at least 3 months. This means that you cannot expect a quick effect from the drug.

The medicine is approved for pregnant women, lactating women and children over 12 years of age. It should not be used only if you are intolerant to benzoyl peroxide.

Baziron AS does not cause systemic side effects, but local negative manifestations are possible. These include:

itching after application,
burning,
local hyperemia of the skin,
dryness,
the possibility of developing a contact inflammatory process on the skin, dermatitis.

When using the drug, insolation is prohibited, so its use in the summer is fraught with difficulties .

Release form and cost

The product is available in the form of a gel in a plastic tube of 40 grams with an active substance concentration of 2.5%. The manufacturer is a French company.

Comparison of safety of Baziron AS and Skinoren

The safety of a drug includes many factors.

At the same time, for Baziron AS it is higher than for Skinoren. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Baziron AS, as well as Skinoren, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Baziron AS has fewer risks when used than Skinoren.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Baziron AS and Skinoren.

What is the difference between the drugs

The first difference between the presented drugs is their price. The cost of Baziron is 460 rubles, and for Skinoren you will have to pay 680 rubles. In addition, their composition is also different. Skinoren is made on the basis of azelaic acid, but Baziron contains benzoyl peroxide. Although many experts note that these funds can replace each other, this opinion is considered erroneous, because they have different effects. Baziron directs its action to eliminate all bacteria that affect the formation of inflammation, and Skinoren allows you to change the structure of the glands and reduce the production of sebaceous secretions.

Comparison of addiction between Baziron AS and Skinoren

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values of such parameters as “o syndrome” in Baziron AS is quite similar to the similar values in Skinoren. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Baziron AS has a fairly low value of the syndrome, just like Skinoren.

Side effect of the drug -

When using the drug, local skin irritation is possible, which is normal. Frequent symptoms of irritation include flaking and dry skin, redness, and a burning sensation. More rare symptoms include skin soreness and contact dermatitis. Rarely, allergic contact dermatitis may occur, which will require discontinuation of the drug.

In order to prevent or reduce the symptoms of irritation, we recommend that you start using Baziron AS with a 2.5% concentration of benzoyl peroxide. If symptoms of irritation do occur, then within 1-2 weeks you can switch to a single use of the drug (once a day), then returning to use 2 times a day (of course, if this was initially necessary).

Important : Benzoyl peroxide increases skin sensitivity to the sun. This means that when using the drug during periods of high solar activity, hyperpigmentation of the skin in the areas where the drug is applied is highly likely. Therefore, you will need to use sun protection products - no less than SPF 50; face-shading glasses, a Panama hat or a cap will also be useful. Let us remind you that products with SPF must be non-comedogenic (not clog pores), otherwise we will get an exacerbation of acne.

A good product SPF 50 for acne (in the form of a suspension) –

Contraindications for use –

allergy to one of the components of the drug,
children's age up to 12 years.

Special instructions - the drug can only be applied to the skin (not to the mucous membrane and red border of the lips). In case of contact with the mucous membranes of the nose, eyes, or mouth, rinse immediately with water. In addition, it is undesirable to use Baziron AC in parallel with products that have a drying, exfoliating effect, or alcohol-based products, because this will increase the irritant effect of the drug.

Use during pregnancy and lactation –

The drug has extremely low absorption from the surface of the skin, due to which it practically does not enter the bloodstream and does not have a systemic effect on the body. However, a large amount of breakdown products of benzoyl peroxide, namely benzoic acid, enters the body. No safety studies have been conducted during pregnancy and lactation. We hope that our article on the topic: Baziron AS price reviews was useful to you!

Sources:

1. Higher medical education of the author of the article, 2. Textbook on dermatology “Fitzpatrick's Dermatology” (8th edition), 3. “Etiology, pathogenesis, classification and clinical picture of acne vulgaris” (Barinova A.N.), 4. “Acne from the position of evidence-based medicine" (Anisimova M.Yu.), 5. "Modern methods of treatment and rehabilitation of patients with acne vulgaris" (Barinova A.N.).

Comparison of side effects of Baziron AS and Skinoren

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Baziron AS has almost the same side effects as Skinoren. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Baziron AS is similar to Skinoren: how quickly the body recovers after taking it and whether it recovers at all.

Features of the second drug

Skinoren is also a trade name. The medicine is based on one substance – azelaic acid.

Just like benzoyl peroxide, which is part of Baziron, the substance has a full-fledged destructive effect on the main causative agents of acne.

In addition to the antibacterial effect, Skinoren has the following effects :

softens the skin,
removes dead skin flakes,
normalizes the functioning of the sebaceous glands,
eliminates hyperpigmentation.

The drug is not absorbed at all, it acts only locally , so the product is absolutely non-toxic, overdose is completely excluded.

How is Skinoren used?

The medicine is applied to problem areas twice a day in a very thin layer. To enhance the effect, you need to lightly rub the drug.

Before application, the skin should be treated with lotion or alcohol and then dried.

The minimum course of therapy is 1 month. For full results, you need to use Skinoren for six months.

The drug can be used by pregnant and lactating women, but it should not be applied to the nipple area. Children are allowed to use only from 12 years of age.

The drug has no contraindications except for hypersensitivity to azelaic acid. It causes virtually no side effects, although skin irritation and rash at the site of use are possible. However, these phenomena are short-lived and do not require discontinuation of the medication.

Release form and cost

The drug is produced in Italy for a German company.

Available in the form of 15% gel and 20% cream . Both forms are packaged in 30 gram tubes. Instructions for use are included with the medicine.

The average cost of both gel and cream is about 1000 rubles .

Comparison of ease of use of Baziron AS and Skinoren

This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.

The ease of use of Baziron AC is approximately the same as Skinoren. However, they are not convenient enough to use.

The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.

Last update date: 2020-12-04 13:42:49

Skinoren

The main component of the drug is azelaic acid. When applied to the skin, it is able to penetrate the epidermis and dermis, where it has a therapeutic effect. If the skin is damaged, the penetration of the active substance occurs faster and deeper.

The mechanism of action of this substance is unknown. The acid is believed to affect the production of free forms of oxygen, have an anti-inflammatory and antibacterial effect, and at the same time suppress the growth and division of abnormal skin cells.

In addition to the main effect, azelaic acid is capable of:

Regulate sebum production.
Slows down the development of age spots, although it has virtually no effect on those that have already appeared.
Promote self-cleaning of the ducts of the sebaceous glands.

The main indication for Skinoren is acne, including those accompanied by inflammation, but it helps prevent the formation of blackheads and pigment spots on the skin.

Despite the fact that Skinoren is a topical drug, some of it can penetrate into the bloodstream. For a single use, 5 g. gel, approximately 3.6% of the total proportion of azelaic acid enters the body.

Azelaic acid did not show any adverse effects in clinical trials. However, the potential risk of using the drug for humans is unknown. Therefore, pregnant and lactating women can use Skinoren only after consulting a doctor, in cases where the benefits of treatment outweigh the likelihood of side effects.

How to use Skinoren

The cream or gel should be applied only to clean, dry skin. After using the drug, you must wash your hands with soap, and the application area should not be covered with a bandage.

The gel or cream is applied twice a day - in the morning and in the evening. For application to the face, a strip 2.5 cm long is enough; the composition can be lightly rubbed into the skin. This regimen is also suitable for the treatment of acne in adolescents aged 12-18 years.

The minimum duration of treatment for acne is one month, longer use is allowed.

The use of the drug in the treatment of melasma should last for at least three months, rosacea - for at least two months.

If irritation occurs during treatment, it is necessary to reduce the amount of the drug applied or reduce the number of applications to once a day.

If Skinoren is prescribed for the treatment of increased pigmentation, then to prevent exacerbation or relapse it is necessary to use sunscreen.

Types of the drug Skinoren

Skinoren is produced only for the purpose of application to problem skin. The pharmacy sells gel and cream of the same name.

The main component in both drugs is azelaic acid. One gram of gel contains 150 mg of acid, one gram of cream contains a little more - 200 mg.

The 15% gel also contains: triglycerides, sodium hydroxide, lecithin, propylene glycol, disodium ededate, polyacrylic and benzoic acids, polysorbate and purified water.

The gel is a mass of grayish or slightly yellowish color with a weak medicinal odor, opaque. You can buy it in tubes of 15, 30 or 50 g, placed in a box complete with instructions.

Cream 20% additionally contains: benzoic acid, glycerol, macrogol glyceryl stearate, propylene glycol, a mixture of cetostearyl alcohol and coconut oil fatty acid glycerides, cetostearyl ethyl capronate and purified water.

Skinoren cream has a uniform structure and white color. Sold in 30 g aluminum tubes, placed in a cardboard package along with instructions.

What's better?

Zenerit, Skinoren or Baziron - which is better? Which is more convenient to use and which will ultimately be more effective? The answers to these questions depend on exactly how your acne manifested itself and what triggered it.

Skinoren and Baziron are good because they are not addictive and can be used in repeated courses indefinitely. However, Zinerit is more convenient to use, and its therapeutic effect occurs faster. In addition to this:

If, in addition to acne, pigment spots are bothering you, then using Skinoren you can make them less noticeable.
If you are going to travel to hot countries or it is summer on the calendar, then it is better to use Skinoren or Zinerit, as Baziron makes the skin more sensitive to the sun.
If you suffer from hyperhidrosis, that is, increased sweating, then again you should give up Baziron, as it is sensitive to excess moisture and may not have the expected effect.
If you are allergic to antibiotics, especially the macrolide group, which includes erythromycin, then Zinerit should be used with caution or choose another remedy.
If you have oily skin, it is better to choose Zinerit or Skinoren gel, which have a mattifying effect. And for dry skin, on the contrary, Baziron AC cream is more suitable.

Which remedy to choose for treatment will depend on many factors. Perhaps only a dermatologist can take them all into account. Therefore, in order to purchase the most effective drug, it is best to seek advice from a specialist.

Zenerite

Another fairly popular drug for the treatment of acne. It is a powder for preparing lotion. The main active ingredients are erythromycin and zinc acetate.

The first substance is a broad-spectrum antibiotic that has a bacteriostatic effect on microorganisms that provoke the development of acne. The second component also has the ability to inhibit the growth of microorganisms, but, in addition, it also has an anti-inflammatory effect.

Thanks to its two-component composition, Zinerit helps:

Cope with inflamed acne and comedones.
Accelerate the process of restoration of damaged skin, since zinc has the ability to accelerate regeneration and is additionally a good antioxidant.
Reduce the work of the sebaceous glands.

Thanks to its liquid form and a bottle with a special applicator, the drug is easily applied to the skin, dries quickly and leaves no traces. It can be used during pregnancy and lactation.

Composition and release form

The drug Baziron AS is available in the form of a gel, which spreads evenly over the skin and has a therapeutic effect.

In addition to the gel skin treatment, you can purchase the following forms of the product:

Lotion for cleansing the face of sebum Baziron AS;
Cleanser Baziron AS;
Scrub for deep cleaning Baziron AS;
Cream Baziron AC.

The drug has the following composition:

Benzoyl peroxide;
Glycerol;
Acrylate copolymer;
Carbomer;
Poloxamer;
Silicon;
Purified water;
Propylene glycol;
Sodium hydroxide.

However, the most penetrating component is benzoyl peroxide.

Gel for the treatment of problem skin is available in the following forms:

Gel for external use 2.5%;
Gel for external use 5%;
Gel for external use 10%.

Why is Baziron AC effective against acne?

The medicinal gel is widely prescribed by specialists to eliminate defects in problem skin. This is due to the large amount of benzoyl peroxide included in the product.

Thanks to this component, the secretion of the sebaceous glands is affected, due to which the secretion of fat is reduced, and the skin begins to receive more oxygen.

Penetrating into the epidermis, the components have an anti-inflammatory effect and eliminate bacteria that contribute to the appearance of skin defects.

The use of Baziron As allows you to achieve the following tasks:

Improves the supply of oxygen to the layers of the epidermis;
The natural process of restoration of epidermal cells is launched;
Helps narrow pores, thereby eliminating scars;
The inflammatory process is reduced;
Normalization of the functioning of the sebaceous glands;
Skin moisturizing;
Eliminate germs that cause acne;
The spread of germs to healthy areas is blocked;
Pore cleansing;
Dries purulent formations;
Elimination of dead epidermal cells;
Promotes the resorption of comedones;
Removes toxins from the epidermis.

Widely used to prevent the appearance of inflammatory processes, especially in adolescence.

Which drug should I choose?

There is a wide selection of different drugs on the medicine market to combat problem skin. Therefore, the patient is faced with the question of which drug to choose? Let's compare some of them.

Which is better Baziron AC or Differin?

Both drugs are well tolerated by the skin and are not addictive, so they are used for long-term treatment. Medicinal substances have different active components, therefore they have different effects on the cause of acne formation.

The combined use of these substances is not permitted.

Experts differ in their opinions regarding which remedy is more effective. Both drugs are aimed at solving similar problems and require an individual prescription from a doctor.

The preference when choosing a drug is given depending on the type of problem. For example, Baziron AS effectively eliminates acne and pimples, and Differin, in turn, reduces the number of vulgar acne and helps eliminate age spots.

Therefore, the choice of drug for the treatment of problem skin depends on the patient’s personal preferences.

Which is better Baziron AS or Zinerit?

When comparing two medicinal substances, such as Zinerit and Baziron As, it should immediately be clarified that these two substances are aimed at different effects on the epidermis.

Zenerite fights surface problems and eliminates bacteria that are located inside the pores. Baziron AS, in turn, effectively eliminates the causes of inflammatory formations inside the skin layers and on the surface.

Application Zinerit has the property of being addictive, which makes it unsuitable for long-term use. Therefore, many dermatologists advise using Baziron As to eliminate skin defects.

What is better Baziron AS or Skinoren?

The use of these two drugs depends on the individual characteristics of the skin, therefore, before choosing a product, it is recommended to undergo appropriate diagnostics, based on the results of which the doctor will prescribe the most effective remedy.

Experts advise that if the use of Baziron AC does not bring the necessary results, then you need to use Skinoren.

If you have a large area of skin that has been affected by acne, it is more effective to use Skinoren, since it can be applied to the entire area of the epidermis in large quantities; Baziron AS is recommended to be applied only to places of inflammatory formations.

One of the advantages of Baziron AS is the ability to choose the most appropriate dosage of the product and its ability to moisturize the skin, while Skinoren dries the skin and can cause peeling. Also, very often, with sensitive skin, dryness and burning may occur at the application sites.

Mechanism of action

The medicine is used only for external application.

The active components of the substance tend to penetrate deeply into the layers of the epidermis and turn into benzoic acid.

The action of this type of substance eliminates the causes of inflammatory formations and has a therapeutic effect on the skin.

Proper use allows you to eliminate bacteria that form in the pores due to the large secretion of sebum.

Benzoyl peroxide blocks further damage to healthy areas of the epidermis, and starts the natural process of restoration of cell membranes.

The action of the active components removes dead cells, which very often clog the pores of the epidermis and contribute to the appearance of blackheads and acne.

Correct use of the substance allows you to saturate the skin with oxygen and increases blood flow to problem areas, thereby improving the therapeutic effect on the skin.