Compound
The cream for external use contains the active component ciclopirox olamine , as well as a number of additional components: liquid paraffin, cetyl alcohol, myristyl alcohol, benzyl alcohol, lactic acid, stearyl alcohol, polysorbate 60, sorbitan stearate, water.
Batrafen varnish contains the active component ciclopirox and a number of additional components: ethyl acetate, copolymer of butyl hydromaleate and methoxyethylene, isopropanol.
How does varnish work?
Batrafen nail polish, according to reviews, is effective against microorganisms sensitive to cycloperox, and has a high medicinal concentration of the main active ingredient (8%) - cycloperox olamine.
Thanks to its liquid texture, the drug easily penetrates into the thickness of the nail and nail bed, where the most viable fungal infection is located. The varnish reliably seals the plate of the affected nail, preventing the supply of oxygen to microorganisms, which disrupts the process of their reproduction.
In this way, the infection cells are destroyed, mature spores are destroyed and the transport of substances necessary for their life is disrupted. The antibacterial effect of the product extends to mold and yeast-like fungal infections, as well as Trichomonas and mycoplasmas.
The drug is effective against:
- dermatophytes;
- streptococci;
- staphylococci;
- fungi such as Candida;
- pathogens of microsporia;
- sporotrichosis;
- trichophytosis;
- mycetomas.
pharmachologic effect
The medicine has an antifungal effect.
The product has a wide spectrum of influence and has good penetration ability. The antifungal effect of Batrafen is associated with inhibition of entry into the cell and induction of removal from it of components that are necessary for the functioning of the cell.
The active component of the drug ciclopirox olamine is effective against yeast-like fungi, dermatomycetes, molds, and other species. There is also an antibacterial effect against most gram-negative bacteria and gram-positive microorganisms.
Pharmacodynamics
Cream for external use. Batrafen is a broad-spectrum antifungal agent with good penetrating ability. The active ingredient ciclopirox olamine is effective against dermatomycetes, yeast-like, mold and other types of fungi. It has an antibacterial effect against gram-positive strains of bacteria and most gram-negative pathogens.
Nail polish. Broad-spectrum antifungal drug. Active against Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton tonsurans, Trichophyton quinckeanum, Trichophyton equinum, Trichophyton concentricum, Trichophyton epilans, Trichophyton ferrugineum, Trichophyton gallinae, Trichophyton schoenleinii, Trichophyton soudanense, Trichophyton terrestre, Trichophyton violaceum, Microsporum canis, Microsporum gypseum , Microsporum audouinii, Microsporum langeronii, Microsporum nanum, Epidermophyton floccosum, Candida (Candida albicans, Candida tropicalis, Candida krusei, Candida parapsilosis, Candida pseudotropicalis, Candida lipolytica, Candida guilliermondii, Candida brumpti, Candida utilis, Candida viswanathii), C ryptococcus neoformans, Histoplasma capsulatum, Sporotrichum schenckii, Torulopsis glabrata, Blastomyces dermatitidis, Paracoccidioides brasiliensis, Saccharomyces cerevisiae, Torula bergeri, Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, Penicillium chrysogenum, Penicillium notatum, Absidia corymbifera, Mucor miehei, Pae cilomyces variotii, Fusarium solani, Madurella grisea, Madurella mycetomatis, Allescheria boydii, Cladosporium carrionii, Cladosporium trichoides, Phialophora jeanselmei, Phialophora pedrosoi, Phialophora gougerotti, Hormodendrum dermatitidis, Pyrenochaeta romeroi, Leptosphaeria senegalensis. The antifungal effect of ciclopirox is based on inhibiting the entry into the cell and inducing the removal from the cell of components necessary for its life. It has an antibacterial effect against gram-positive and most gram-negative pathogens. Suppresses the development of mycoplasmas and trichomonas.
Pharmacokinetics and pharmacodynamics
After Batrafen cream has been applied to a large surface of the skin and left for 6 or more hours, it may enter the bloodstream in small doses - approximately 1.3%. It is approximately 94–97% bound to plasma proteins in the body, the half-life is 1.7 hours. It is excreted in the urine.
Provided that nail polish is used for one day, the fungicidal concentrations are 20–30 times greater than plasma Cmax. of mycosis within 48 hours .
Manufacturer
Cream. Aventis Pharma Ltd., India. Plot No. C-1, Madkaim Industrial Estate, Madkaim, Mardol Post, Ponda, Goa - 403404, India.
Nail polish. Sanofi-Aventis Deutschland GmbH, D-65926, Frankfurt am Main, Germany.
Consumer complaints should be sent to the address in Russia: 125009, Moscow, st. Tverskaya, 22.
Tel.; Fax.
If the drug is packaged at Pharm CJSC, consumer claims should be sent to the address: 141345, Moscow region, Sergiev Posad district, Svatkovo village, p/o Svatkovo.
Tel/fax
Instructions for use of Batrafen (Method and dosage)
Antifungal agents Batrafen are used externally only.
Batrafen cream, instructions for use
The product in the form of a cream should be applied to areas that have been affected by the fungus twice a day. After application, dry the area treated with cream. It is necessary to practice therapy until the symptoms of the fungal disease disappear. Typically, treatment lasts about two weeks. To prevent recurrence of the disease, it is advisable to use the cream for another 1-2 weeks after the signs of the disease disappear.
Varnish Batrafen, instructions for use
Before applying varnish to the surface of the nail plate, you need to remove as much of the affected nail as possible, and file the remaining nail plate so that it is uneven. The product should be applied to the nail affected by the disease once a day, every other day, practicing this regimen during the first month of treatment. In the second month, varnish should be applied 2 times a week, in the third month – once a week.
During the treatment, once a week, the varnish must be removed using a solvent and the overgrown part of the nail plate must be cut off. If the varnish is damaged during the period between its application, only the part of the plate that was cleared of varnish should be coated with the product.
Treatment continues until symptoms disappear, but not longer than six months.
About the use of the drug Batrafen for nail diseases.
Ph.D. Ostroverkhov O.P.
LET'S TAKE A CAREFUL LOOK AT OUR NAILS! When they talk about the beauty of a person, they mean the beauty of the face, the harmony of the body and legs. A beautiful body does not tolerate flaws, even the smallest and most inconspicuous ones. Even having beautiful hands and slender legs does not save you from the repulsive effect if your gaze accidentally falls on unhealthy nails.
Some women are downright horrified when their nail accidentally breaks or begins to peel. This, of course, is annoying, but it’s much more unpleasant when your nails become seriously ill for a long time. Most often this occurs due to fungi. A nail is a horny plate that lies on the nail bed and grows from the nail root. There are many blood vessels and nerve endings at the root and bed of the nail. Therefore, the nails are very sensitive, with the exception of the free edge, which is not connected to the bed and can be cut off painlessly.
A healthy person's nails are pink, shiny, smooth and fully consistent with the shape of the finger. In older people, superficial longitudinal grooves and stripes sometimes appear in the nail plate. The nail grows at a rate of about 0.1 millimeter per day and is completely renewed from the root to the free edge, usually in 170 days. Young people's nails grow faster than older people's, and men's nails grow faster than women's. Faster in summer than in winter.
What happens to nails with fungal diseases?
Smooth and pink nails become dull, yellowish, thickened and split. But “fungus” is not just an annoying cosmetic defect, but a serious disease that requires long-term treatment, which must be started immediately as soon as you discover this illness.
They are transmitted from a sick person to a healthy person most often in a swimming pool, bathhouse, sauna, nail salon, or through shared shoes. The latter especially applies to clothing markets, where one pair of shoes can be on the feet of more than a dozen people before being sold! And if one of them has a fungal infection of the feet, then the chance of getting a fungal infection in the “lucky” owner of this pair is very high. Such a “gift” may not manifest itself in any way for a very long time, because a healthy body does not allow the fungus to develop.
Vascular diseases and varicose veins, cuts and wounds can also affect the occurrence of fungal diseases. Boots, boots, leatherette shoes, synthetic tights, socks - all this leads to severe sweating of the feet. When the feet “do not breathe,” they are almost always wet, and a microclimate arises on the surface of the skin, which creates ideal conditions for the growth of fungi.
Pathogenic microorganisms and fungi are present on the skin of every person, however, they do not always cause diseases. The development of infection is possible with a general weakening of the body's defenses. Colds, lack of vitamins - all this leads to a decrease in immunity, and as a result - to the development of fungal infections of the nails (onychomycosis). If the fungus is not treated, it can gradually spread throughout the entire body, causing a number of serious disorders, such as allergic reactions, stomatitis, and respiratory diseases. Dealing with this adversity is not easy.
Fungal spores can withstand drying, heating to 100 and freezing to minus 60 °C. What to do? In some cases, especially if the patient is negligent about his health, it is necessary to resort to surgical intervention - nail removal. In order to prevent this, treatment must begin at the earliest possible stage of the lesion, when the nail plate is not yet deeply affected by the fungus. Currently, high-quality drugs have been developed and are effectively used to treat fungal infections.
How to treat an infected nail? Take pills, use ointments? In some severe cases, antifungal tablets are necessary, but, unfortunately, in the vast majority they are very toxic, causing irreparable damage to a number of internal organs. Antifungal ointment is not fixed on the nail, as it is easily wiped off from its surface, for example, with a sock.
The best dosage form for the local treatment of onychomycosis is varnish, since it remains on the nail for a long time, effectively penetrates under the nail plate and is easy to use. One of the most famous and effective varnishes in Russia is Batrafen varnish. Quite a long time passes from the start of treatment until healthy nails fully grow, so the treatment process requires persistence and patience.
Before applying Batrafen varnish for the first time, the affected nail must be cut as short as possible with scissors. After this, the entire surface of the nail is filed with a nail file (don’t forget to treat the scissors and nail file with alcohol after the procedure). A thin layer of varnish (no longer required) is applied to the affected nail in 1-2 strokes. Once a week, remove nail polish with a regular solvent and repeat the procedure with scissors and a nail file. The treatment regimen is as follows: 1 month - varnish is applied to the nails every other day; 2 months - varnish is applied to the nails 2 times a week; 3 month - varnish is applied to the nails once a week. Usually one bottle of Batrafen varnish is enough for a three-month course of treatment. Do not forget to close the bottle tightly after using the varnish to prevent the varnish from drying out. Batrafen varnish can be used not only for treatment purposes, but also for the prevention of fungal infections when visiting saunas, swimming pools and other public places where you have to walk barefoot. For women, the use of Batrafen varnish will not be an obstacle to the application of cosmetic varnishes, which can be applied to medicinal varnish.
In conclusion, one more important question: is it really so important to treat affected nails if it does not cause discomfort and the patient is not interested in cosmetic issues? First of all, such a person can transmit a fungal infection to his loved ones. If you don’t care about your own health, think about your children, about your parents (in old age, fungal infections are especially severe and difficult to cure). If a patient has a fungal infection only the nails are affected, then in his relative the infection may affect the feet, palms and fingers. The final decision about the presence of a fungal nail disease can only be given by an experienced dermatologist, so in all cases of changes in the nails, contact a specialist. So let's take a closer look at our nails!
Analogs
Level 4 ATX code matches:
Mikonorm
Undecin
Gentian violet
Zinkundan
Exoderil
Exiter
Lotseril
Lamisil Dermgel
Lamisil Uno
Lamisil
Salicylic acid
Salicylic ointment
Keto Plus
Exifin
Fungoterbin
Mycoseptin
Thermikon
Nitrofungin
Sulsena
Baziron AS
Analogues of the drug Batrafen in the form of an ointment are the drugs Ciclopirox , Dafnedzhin .
An analogue of Batrafen varnish is Loceryl .
Which is better: Batrafen or Lotseril?
Lac Loceryl affects the structure of the fungal cell membrane, as well as the process of their biosynthesis. The active ingredient of the drug is amorolfine . In general, the effect of this drug is similar to that of Batrafen, and its price is slightly higher.
Indications
According to the instructions, the varnish is used to eliminate the symptoms of the following diseases:
- pityriasis versicolor;
- fungal nail diseases;
- dermatosis;
- fungal vaginitis and vulvovaginitis;
- candidiasis;
- tinea pedis.
The drug is used as a basic, prophylactic and additional agent in complex therapy for the treatment of all types of fungal infections.
When to start treatment
The sooner treatment is started, the faster the fungal disease can be eliminated and the development of a chronic form can be prevented. To determine the type of pathogen, consultation with a dermatologist or mycologist is necessary. With the help of laboratory tests, the doctor will be able to identify the causative agent of the fungal infection.
At the appointment, the dermatologist conducts a visual examination of the patient and pays attention to symptoms. To make a correct diagnosis and select effective treatment, a scraping is taken from the affected nail.
Laboratory methods for determining fungus:
- microscopic examination;
- clearance with a special Wood's lamp;
- cultural study - culture of scrapings.
In case of self-medication, there is a possibility that the fungal pathogens will not be completely destroyed. This is fraught with complications and the disease becoming chronic.
Healthy nails have a smooth nail plate and a natural pink tint. When affected by a fungus, the plate becomes dull, then yellow spots appear. The nails begin to thicken and split. Batrafen nail polish, according to the instructions and reviews, can be used not only as the main remedy, but also as a preventive measure against fungal nail infections.
special instructions
Treatment with Batrafen varnish is more effective the earlier it is started. The drug will show a good result if the area covered by fungal microflora occupies no more than 70% of the nail plate, and its base (matrix) and surrounding skin are not infected. With a larger coverage area, antifungal therapy in the form of tablets and ointments must be added to the medicinal varnish.
The varnish can only be used externally. Contact with mucous membranes must be avoided.
During treatment, you should not use manicure varnish or extend your nails, as the effectiveness of treatment with Batrafen is reduced.
All means and instruments during treatment must be strictly individual. After use, it is important to ensure disinfection of materials and treatment areas. It is useful to combine treatment with Batrafen varnish with taking vitamins and medications that increase immunity.
Side effects
Batrafen nail polish rarely provokes complications and unpleasant reactions.
Side effects include skin manifestations:
- itching;
- burning;
- peeling;
- redness;
- irritation;
- edema;
- allergic reaction.
If such symptoms occur, you should stop using the product and change to a similar drug suggested by a dermatologist.
To reduce the likelihood of such manifestations, apply varnish only to damaged areas of the skin and nail plate.
Contraindications
Batrafen nail polish is an effective and safe product, but it has a number of contraindications.
It cannot be used:
- during pregnancy;
- during breastfeeding;
Batrafen nail polish should not be used during breastfeeding. - children under 10 years old;
- persons with individual intolerance to components.
