The drug “Restylane” is a biogel created on the basis of hyaluronic acid and allows you to correct both superficial and deep wrinkles. Its action is like a magnet that attracts microparticles of water, resulting in smoothing of the skin at the injection sites. All components are completely compatible with the tissues of the human body, which makes its use absolutely safe. The final products after digestion of the drug are only carbon dioxide and water.
This product is supported by its approval by the FDA of the United States Department of Health and Human Services. Having previously conducted a series of studies, experts from this authoritative organization unanimously recognized the safety and high effectiveness of the anti-age drug Restylane. Over the years since its invention (and this was more than 20 years ago), about 12 million successful procedures have been carried out.
Separately, it is necessary to note the complex effect of Restylane, which is equally effective both for correcting wrinkles and for increasing volume. At the same time, both specialists and patients note its immediate effect: after injections, wrinkles are rapidly smoothed out, the skin becomes elastic and youthful; lips acquire natural plumpness. The effect is noticeable not only directly in the area of drug administration, but also in neighboring areas.
In order to give volume to tissues, previously only synthetic gels (silicone, acrylic) were used. But since they are foreign to the body, their use caused many problems (compression, inflammation, migration), which were often solved only through surgery. The need for natural drugs led to the fact that in the 90s. (Sweden) developed Restylane, reviews of which today are beyond praise. The first tests showed the obvious advantage of biogel. In addition, the hyaluronic acid in it is not of animal origin.
Please note that due to its balanced composition, critical dosages are never used when carrying out cosmetic procedures with biogel. If the volume of the administered substance is insufficient, additional injections are given. They are carried out immediately, without waiting for the already injected substance to be absorbed.
"Restylane", in contrast to artificial drugs:
- Perfectly compatible with human tissues
- Does not interfere with biochemical processes, allowing cells, oxygen molecules, hormones and nutrients to move freely
- Normalizes metabolism in the skin
- Sterile
- Does not cause allergies and does not contain protein impurities
- Does not contribute to the formation of compactions and inflammation of the skin around the injection site
- The number of injections is not limited; an additional volume of the drug can be administered without waiting for the previous portion to be completely absorbed
- The injected volume of gel can be reduced using a natural enzyme that destroys hyaluronic acid
- After the end of its action, the drug disintegrates without any residue into neutral substances - water and carbon dioxide.
Use of hyaluronidase in case of unsuccessful results
In case of a possible unaesthetic appearance, migration of the gel under the skin or inflammation, the patient wants to return to its previous appearance. For this purpose, hyaluronidase of animal origin is used. The enzyme accelerates the biodegradation of HA: it decomposes it into enzymes, after which they are excreted by the blood and lymph flow . Hyaluronidase powder is dissolved with saline before being introduced into the corrected area by injection or sonophoresis (with ultrasound). The drug is able to remove the filler within 2 days.
The method also has a negative side, since the solution can cause swelling that persists for a long time. In addition, uneven filler removal is possible, which is especially noticeable on the lips. If the patient is prone to allergies, then hyaluronidase must be administered along with antihistamines.
Restylane filler
Today, the product is one of the most popular fillers (dermal fillers) for contouring. Its purpose is to restore the lack of volume in problem areas of the face by penetrating under the epidermis and filling cavities in wrinkles and folds.
All such drugs have different compositions, characteristics, methods of carrying out the procedure, principles of action, pros and cons of use.
The filler must have certain qualities that must be taken into account when choosing:
- the absence of components that can cause an allergic reaction, as well as carcinogenic substances;
- good biological compatibility with tissues of the human body;
- ability to be completely absorbed;
- ability for long-term storage.
There are three types of fillers:
- permanent – consisting of both natural and synthetic components;
- temporary - have the highest degree of security, which is why they are the most popular, even despite the short validity period (up to 0.5 year);
- permanent - special biogels consisting only of components of synthetic origin (polymers).
The series, in addition to the basic drug of the same name, also includes other types of fillers. We provide a list of them below in the table.
Type of filler Restylane | Main areas of use |
Touch* | For the correction of superficial wrinkles |
Perlane** | For the correction of deep wrinkles, folds in the lip area and between the eyebrows, and the contours of the chin. Duration of action: 4–6 months. more than the basic Restylane filler |
SubQ | For correction of cheeks, cheekbones and facial contours |
Lipp | To improve and increase lip volume |
Vital | For mesotherapy procedures and biorevitalization |
Vital Light | |
Lip Volume | The latest generation product for lip correction. Designed to accommodate high muscle activity in the nasolabial area |
Lip Refresh |
* low viscosity filler
** high viscosity filler
"Restylane Touch" is used for superficial skin problems to fill shallow folds and fine wrinkles in the corners of the eyes, facial wrinkles around the mouth. Suitable for those with thin skin.
Restylane Perlane is used for more serious problems to improve the shape of certain areas: cheekbones, chin. Effectively eliminates glabellar and nasolabial folds, deep wrinkles. It is injected deeply and absorbs longer than other fillers in this series.
"Restylane Sub Q" is a product for improving the contours of the face and replenishing volume in certain areas, mainly the cheekbones and chin. Recommended for deep injections. The advantages of the drug include a short recovery period after the procedure, safety, predictability of the result, ease of use, and duration of the effect. No preparation is required for the procedure.
"Restylane Lip" is designed for correction of the lip area (mainly for augmentation). It is based on a special formula that prevents rapid resorption.
Indications for use:
- the need for lip correction and augmentation;
- wrinkles around the mouth;
- "folds of sorrow";
- fold on the chin;
- drooping corners of the mouth.
The duration of action of “Lip” is one year.
"Restylane Vital" is an innovative product, a colorless gel based on hyaluronic acid. Helps improve tone, moisturizes, promotes skin elasticity, fills with energy, radiance and freshness. Has a wide range of indications:
- dehydration;
- photoaging;
- rehabilitation of facial skin after injuries, laser exposure, visits to a solarium.
Suitable for eyelids, décolleté, cheeks, forehead, lips, nose, neck, chin, back of hands.
An important advantage of the drug “Vital” is its effectiveness regardless of skin type, including oily skin, which provokes acne. Recommended for young patients to prevent early aging.
"Restylane Vital Light" is a natural remedy for those with thin and highly sensitive skin. Increases tone, gives the skin a healthy appearance, improves elasticity. Indications for use are anti-aging prevention in young patients, thin skin in the décolleté, neck, and arms.
Restylane Lip Volume is a subdermal filler designed to improve the shape of the lips and give them natural volume. Contains lidocaine, which makes the injection procedure absolutely painless. Gently and evenly fills the voids between fabric fibers. Thanks to modern production technology, hyaluronic acid (the main component of Lip Volume) becomes completely compatible with body tissues. Duration of action – from 6 to 9 months.
“Restylane Lip Refresh” is a recently presented new generation filler, created not for augmentation, but for rejuvenation of the skin of the lips. Today there are no analogues to this drug in the world. The duration of action of Lip Refresh is not very long - up to 4-5 months. But during this time it acts very effectively: it makes lips soft, elastic, normalizes and maintains skin hydrobalance.
Precautionary measures
The patient must inform the cosmetologist about the treatment (drug) and procedures being taken before undergoing contouring. You should trust the injection of fillers only to an experienced specialist to avoid an ugly result ! After the procedure, the doctor must destroy the used syringe with needle and auxiliary materials.
To prepare the tissues before the filler is introduced and after the procedure, it is necessary to perform a professionally correct massage of the corrected area. The skin should be disinfected.
Restylane injections allow:
- Get rid of crow's feet at the outer corners of the eyes and wrinkles on the eyelids
- Get rid of vertical wrinkles between the eyebrows and horizontal ones on the forehead
- Get rid of wrinkles on the back of the nose and oblique wrinkles on the sides of the bridge of the nose
- Get rid of vertical wrinkles in the corners of the mouth, under and above the lips
- Smooth out nasolabial folds
- Smooth out acne scars
- Change the shape of your lips and make them bigger
- Change the shape of the chin, cheekbones and cheeks
- Prevent deepening of wrinkles on young skin
Restylane injections are contraindicated if:
Inflammatory or infectious process in the area of the intended injection- Bleeding disorder
- Exacerbation of common diseases
- Tendency to develop keloid scars
- Taking antibiotics and anticoagulants
- Pregnancy and lactation period
- Active form of herpes;
- Autoimmune diseases;
- Oncological diseases;
- ARVI;
- Diabetes.
In rare cases, side effects may include pain at the injection site and a feeling of skin tension, redness, swelling, bruising and slight itching. They usually do not require treatment and go away within two days if they occur on the face, or within a week if they occur on the lips.
Side effects
After injections of Restylane Perlane, side effects appear:
- bruises and itching at the injection site;
- noticeable swelling and edema;
- hematoma, hyperemia and slight bleeding;
- excessive increase in the volume of the corrected zone due to incorrect calculation of the drug;
- acne-like papules;
- occlusion of the lumen of the terminal artery when filler enters a blood vessel;
- the appearance of infection in soft tissues due to insufficient disinfection of the skin before injections.
The infection must be treated, excessive increase in volume can be removed with hyaluronidase, and the remaining phenomena will go away on their own after 1-3 days in the skin of the face, after 2-8 days around the lips.
Procedure technology
The injection procedure takes 30-40 minutes. Biogel is injected into the dermis strictly under a fold or wrinkle using successive injections with a thin needle. Using Restylane , lip augmentation is performed by a series of injections into their contours. Anesthesia is usually not needed for injection into fine wrinkles. But when nasolabial folds are smoothed out with the help of the drug or facial features are changed, then either local anesthesia using lidocaine cream or conduction anesthesia is performed. After Restylane injections, reviews of which can be seen on our website, a hospital stay is not required.
Lip correction with Restylane:
After the procedure, the result is noticeable almost immediately, but it becomes most pronounced after a week. Wrinkles become smaller or disappear completely, and lips acquire a seductive appearance after Restylane injections, you can see photos on our website.
The duration of action of the Restylane injection varies from person to person, but usually from 6 to 12 months. The more dehydrated the tissues and the faster the metabolic processes, the faster the effect will pass. At the same time, massages, saunas, electrical procedures and other effects that improve blood circulation in tissues contribute to a greater rate of absorption of the drug.
If you are interested in the drug "Restylane", then you can read patient reviews on the forum of our portal and ask experienced cosmetologists at Moscow clinics. More detailed information and the cost of injections can be found by calling Moscow cosmetology clinics, which can be easily found on our portal.
About precautions, adverse reactions and ways to eliminate them:
- excessive increase in volume of lips and cheekbones is easily eliminated with injections of hyaluronidase;
- redness, itching, swelling are short-term side effects that go away on their own within 6-7 days;
- hematomas and bleeding in the injection area may occur if the patient takes certain medications (aspirin, ibuprofen, naproxen, thrombolytics, etc.). It is always necessary to warn the cosmetologist about taking medications;
- infection of the soft tissues of the face can occur due to poorly disinfected skin before the procedure;
- hyperpigmentation in the injection area sometimes occurs in patients with dark skin; goes away in about a month.
In addition, it should be borne in mind that studies of the safety of Restylane drugs in pregnant and lactating women, as well as in minor patients, have not been conducted. Therefore, it is better for patients in these categories to refrain from performing manipulations.
You also need to know about the US Department of Health restrictions on the volume of gel used:
- 1.5 ml when injected into the lips;
- 6 ml for wrinkle correction.
Contraindications
Beauty injections should not be used if the patient is taking immunosuppressants, aspirin or other blood thinning drugs.
Contraindications also include:
- allergy to hyaluronic acid;
- blood related diseases;
- skin diseases - infectious, inflammatory, tumors, growths in the injection area;
- oncological, autoimmune and mental diseases;
- hypersensitivity;
- herpes;
- fear of injections;
- recent aggressive cosmetic procedures (less than 2 weeks);
- if there is already silicone or other permanent implants at the correction site;
- infectious diseases, as well as chronic diseases in the acute stage.
Attention! There is also no experience testing Restylane on pregnant and nursing mothers, so the drug is also not recommended for use in this category of people.
Photos before and after
Forum member “Gerbera Ani”
Forum member “Fame Fatal”
Forum member “Tanechka_Tanya”
Restylane injections: alternative means
Today, to correct small expression wrinkles in the corners of the eyes (“crow’s feet”), around the mouth, on the forehead and between the eyebrows, Botox injections are often used rather than Restylane gel or other fillers.
For patients with pronounced facial wrinkles, cosmetologists often recommend treatment in two stages: first with Botox, and after three weeks, complete the process of anti-aging therapy with Restylane injections. This practice allows you to get more tangible and long-term results. It has long proven its effectiveness and is rightfully considered the “gold standard” in clinics in Europe and America.
The best treatment option for patients with age-related static wrinkles is the use of subcutaneous fillers. The leading American drug control organization, the FDA, has approved several types of such drugs:
- Restylane
- Hylaform Plus;
- Prevelle Silk;
- Juvederm (Yuvederm).
The most famous and in demand of them today are Juvederm and Restylane - both in Europe and the USA, and in Russia.
Let it last longer!
The main distinguishing property of Restylane products from similar fillers with hyaluronic acid is the duration of the effect obtained . The main biogels from this series have a high density, which makes the process of their disintegration longer.
In addition, the “highlight” is the use of the unique NASHA™ technology, which is patented by the manufacturer of Restylane products - the Swedish cosmetic center Q-Med (part of the Galderma concern). This development is aimed at increasing the period of breakdown of HA molecules.
In the human body this takes about two days. Thanks to an innovative method, Restylane preparations contain a stabilized form of hyaluronic acid. Special “cross-link molecules” are inserted into the structure of its molecules, which firmly connect the acid chains together. Thus, hyaluronic acid can “live” in the dermal tissues from six months to one and a half years.
Reviews
Reviews about the procedure will help you make the right decision.
Forum member “Coroka”
The cosmetologist injected Restylane filler into my lips. It turned out amazing, I still can’t get enough of it, I absolutely love it! The sponges are very tasty. The effect is still there after the procedures. I was worried that the swelling or bruising, God forbid, would linger for a long time after the first procedure, but everything went great. Two friends have already followed my example
Forum member "gertruda"
A couple of days ago I pumped Restylane into my nasolabial folds - I’m very pleased))) the folds have smoothed out and the wrinkles have decreased)) I also want to chip my lips along the contour. The effect was said to last for 7-8 months)))
Forum member “Tanechka_Tanya”
I inject Restylane or Perlane 2 times a year, because... During this time, the drug almost completely “dissolves”, BUT, I can say that my lips are still plumper than the SOURCE! That is, a cumulative effect, apparently! Your lips have become much more attractive than they were!
Forum member “YuliaAks”
I enlarged my lips for the first time with Restylane lipstick at the doctor, I remember they gave me dental anesthesia and used 1 syringe. The effect was either due to swelling or the batch of the drug itself was good, but it came home like a proud duck! And this plumpness lasted for about 1 month. And those around them noticed the lip enlargement and gave compliments).
Forum member “Gerbera Ani”
I enlarged my lips with Restylane 1 ml in May. This was my first time. I really liked the result!
Forum member "annah"
I have 1.5 cubes of Restylane, the main part in the circumlabial area - because wrinkles began to form there early, the rest is in the lips. Everyone who saw me before and after would never have guessed that I have “silicone” in my lips, and only when I say “touch” then they feel some kind of compaction in the skin. And I am very pleased with the result. the shape of the lips in combination with tattooing has become much better. It’s a pity that after six months the gel dissolves
Forum member "riimma"
I went to make my own sponges. The doctor selected the drug Restylane for me during a consultation; there are several types, but this one was said to be the most suitable for me.
Author: Sagitova Patimat Plastic surgeon, maxillofacial surgeon, cosmetologist Chief physician of the cosmetology department of the Lux Clinic. Specialist in laser and hardware rejuvenation methods. Participant of international medical congresses and conferences.
What affects the effectiveness of biorevitalization
The composition itself undergoes biodegradation in the skin, gradually resolves and is eliminated naturally. Because of this, the effect does not remain forever; injections have to be repeated. But it remains possible to correct the ongoing aging processes of the dermis using the following procedures.
How effective the injections will be and how long the results will last depends on a number of conditions:
- the age of the patient, if age-related changes have progressed, more procedures will be required;
- skin condition, preservation of its structures;
- the extent of skin changes, the depth of wrinkles, the severity of the relief of the dermis;
- which specific area of the body undergoes the biorevitalization procedure;
- professionalism and experience of the cosmetologist, the correctness of the sessions.
Effect of the drug Restylane
develops gently, gradually. To obtain a noticeable effect, on average, 3-5 procedures are required with an interval of 2-3 weeks between injections.
Since hyaluronic acid filler is absorbable, repeated microinjections will be required to maintain the achieved results. As a rule, the effect after one full course lasts 6-8 months.
Only a cosmetologist can give a more accurate forecast and number of procedures per course after clarifying the patient’s skin condition.