Relieves anti-wrinkle ointment. Instructions for use, recipes, reviews

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  • 09-10-2020
  • Author: Mysekret Team
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Pimples, blackheads and blackheads are familiar to every person. These defects spoil the appearance and cause concern. To get rid of skin contamination, many cosmetics have been invented, one of which is Radevit cream. The pharmaceutical drug copes well with the above flaws and wrinkles.

Release forms and composition of the drug

Radevit comes in the form of a cream and ointment for application to the skin. The product in the form of an ointment has a delicate, uniform texture. It has no inclusions or foreign impurities. Its color varies from white to a slight yellowish tint.


Radevit anti-wrinkle ointment: recommendations from cosmetologists for use

The cream differs only in its less viscous consistency. Hydrogenated fat and petroleum jelly are not used for its production. The pharmacological action of the 2 forms is the same. At the same time, the cream begins to work faster. Due to its texture, it stains clothes much less.

Radevit, an anti-wrinkle ointment, reviews of which from cosmetologists help evaluate the results of use, is available in an aluminum tube and a cardboard box. No other packaging is provided by the manufacturer. This is important to consider when purchasing to avoid purchasing a fake.

The medicine is sold complete with detailed official instructions for use. There are several volumes of the product: 10, 20 and 35 g.

1 g of the drug includes:

  • 5 mg vitamin E. It is also called alpha-tocopherol acetate. Considered a natural antioxidant. Prevents the appearance of signs of early aging. Protects the skin from the negative effects of free radicals. Helps remove accumulated toxins from the skin. The substance accumulates in the layers of the epidermis. This helps to increase the hydrophobic properties of the skin. Moisture begins to evaporate less from the surface.
  • 50 mg vitamin D2 . Thanks to it, dry skin is reduced and inflammatory processes are relieved. There is also an increase in resistance to various negative environmental factors. The healing process of small cracks and scratches on the surface of the face is accelerated. In the composition of the drug Radevit-Active, the substance is replaced with colecalciferol, also known as vitamin D
  • 10 mg of retinol palmitate or vitamin A. Protects against the appearance of signs of photoaging of the facial skin, makes deep folds and wrinkles less noticeable. Able to retain moisture in epidermal cells. The component is included in many cosmetic products aimed at combating age-related manifestations.

The special texture of the drug is provided by auxiliary components. They are also used to extend the shelf life of the ointment.

Among them:

  • purified water;
  • glycerol;
  • ethanol;
  • Vaseline oil;
  • emulsion wax;
  • butylated hydroxyanisole;
  • butylated hydroxytoluene.

Glycerin and petroleum jelly help the process of skin restoration and moisturizing.

Description of Radevit cream

Radevit cream is an anti-inflammatory, immunostimulating ointment. People call it cream, because many are accustomed to using the medicine as a skin care product. Cream and ointment are one drug that acts equally effectively. There are minor differences between them.

The cream is less viscous and wears off faster from the surface of the skin, and stains clothes less. Enclosed in a convenient tube that allows you to squeeze out Radevit like an ordinary cream. The ointment is sold in aluminum tubes of 10, 20 or 35 grams. The kit includes cardboard packaging and official instructions for use of the medicine.

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Radevit cream has the following effect:

  • Fights allergic rashes and skin inflammations. Radevit has a soft texture, so mothers are not afraid to treat their children with it.
  • Protects the epithelium from external factors, so it is good to use it in winter. Saves from frostbite of the skin, peeling, chapping. The product can be applied to the skin of the entire body.
  • Prevents the appearance of wrinkles and smoothes existing ones.
  • For lips, the cream will be a good balm, softening them, filling them with vitamins and protecting them from cold air currents.
  • Gets rid of acne.

Using the medical drug Radevit, a significant difference is visible within a month. The appearance of the skin becomes fresh because the cream fills the skin with nutrients and moisture necessary for a healthy epidermis. Rough hands become soft, lips soft. Pimples, wounds, cracks heal quickly, wrinkles are smoothed out. The skin acquires a healthy tone and freshness.

Pharmacological properties

The drug has an anti-inflammatory and regenerative effect. Its use can eliminate itching of the skin. The ointment helps strengthen the protective function of the epidermis, normalizes the process of cell death, moisturizes and nourishes the tissues.

Radevit also has other effects on the skin:

  • enhances fibroblast activity;
  • accelerates the recovery process in cells;
  • protects collagen from destruction under the influence of ultraviolet rays;
  • increases elasticity;
  • moisturizes the surface;
  • deeply nourishes;
  • makes the deep layers denser;
  • improves skin tone and texture;
  • enhances the production of elastin, collagen and hyaluronic acid in the body.
  • promotes thinning of the surface layer.

Vitaminized ointment does not have a direct effect on folds and wrinkles. It only moisturizes and activates the natural regeneration process in cells. Due to this, the signs of aging become less noticeable.

Side effects

The medication is usually well accepted by the body, regardless of age. However, every cosmetic and therapeutic product has side effects:

  • If a person has increased skin sensitivity, an allergy may occur, manifesting itself in different ways: skin rash, urticaria, swelling and hyperemia of the epidermis, in rare cases, Quincke's edema and anaphylactic shock may occur. In this case, consult a specialist and select another analogue;
  • If your skin has acute inflammation, then using the cream will increase itching and redness;
  • For pregnant women, the medication is prescribed at the discretion of the dermatologist.

Pharmacodynamics and pharmacokinetics

Laboratory studies on the absorption of the active components of the drug into the human bloodstream have not been conducted. Presumably, the substances are absorbed only in the layers of the skin. There they exhibit a therapeutic effect and activate the cellular metabolic process.

The pharmacological effect of the drug lies in the work of the vitamin composition.

The concentration of active components in the ointment leads to:

  • improving the functional condition of the skin and increasing its elasticity;
  • strengthening the protective function of subcutaneous fatty tissue and skin;
  • normalizing the process of formation of the stratum corneum;
  • reducing severe itching.

Treatment of eczema with Radevit

Eczema

– a chronic skin disease, its occurrence is associated with allergies, that is, an unusual reaction of the skin to ordinary influences. The skin usually performs its function of protecting the body from external influences very well. For eczema to occur, special conditions are needed - a hereditary predisposition to the development of allergic reactions, a special state of the immune system, ready to respond to an irritant with excessive force, sensitization (encountering an allergen in the past) and/or long-term (2-3 weeks) exposure for the formation of the immune system. answer.

What can be allergens?

There are many allergens around us - scientists count more than 5000. They can enter the body in different ways - through the mouth (food, medicines), through the skin (various detergents, dyes, cleaning substances, cosmetics, wool, ointments, creams, deodorants), through respiratory tract (pollen, perfumes, aerosols), by injection, bites.

Why does the disease occur?

The skin usually performs its function of protecting the body from external influences very well. For eczema to occur, special conditions are needed - a hereditary predisposition to the development of allergic reactions, a special state of the immune system, ready to respond to an irritant with excessive force, sensitization (encountering an allergen in the past) and/or long-term (2-3 weeks) exposure for the formation of the immune system. answer. With the long-term existence of the disease, a reaction develops not only to the substance that originally caused it, but also to other substances similar and dissimilar to it.

What happens in the skin?

Bubbles appear in the surface layer of the skin, and inflammation occurs in the depths.

How does the disease progress and how does it end?

Multiple small blisters appear in a certain area of ​​the skin, often the site of allergen penetration. They are located against the background of reddened skin and are always accompanied by itching. When scratching, microorganisms penetrate the skin and crusts appear. After healing, the skin darkens and thickens, with bumps, dryness and flaking. Usually, the initial focus is joined by others, sometimes far from the original focus. If treatment is carried out correctly, itching and inflammation stop. Without treatment, the disease can continue indefinitely, either dying down or flaring up again. Inadequate treatment leads to a new exacerbation after a very short period of time (sometimes after a few days). Except in cases where the allergen is detected at the initial stage of the disease and excluded, there is hardly any hope for a cure. At the same time, it is always possible to improve the condition of the skin and achieve complete disappearance of rashes for a long time.

Is eczema contagious?

Eczema is not a contagious disease, but if infection occurs, and this is a common occurrence in the absence of treatment, then the patient is contagious.

What is the most effective treatment?

Treatment consists of diet, internal and external remedies. If even one component is missing, there is little hope for lasting improvement. During an exacerbation, the diet should be followed by all patients, regardless of whether any food product caused the exacerbation or not. This is due to the fact that some foods can increase itching. Chocolate and chocolate candies, coffee, honey, jam, nuts, citrus fruits, kiwi, pineapples and juices from them, mayonnaise and other seasonings, everything spicy, smoked, pickles, marinades are excluded, the amount of liquid is limited. The method of cooking also matters - it is better if it is boiled and steamed dishes. It must be said that some dermatologists are adherents of a much more strict diet, and sometimes even fasting. Indeed, 2-3 days of fasting are often healing. I believe that when prescribing modern medicines there is no need to follow an overly strict diet, and fasting can only be useful for those patients who have already had experience of fasting in the past and did not suffer from it morally. In addition, a significant proportion of patients have chronic diseases of the gastrointestinal tract, which exclude the possibility of fasting without harm to health. So, the diet is prescribed for the entire period of treatment (usually 1-1.5 months). After this, the prohibited products are introduced gradually - once every 3-4 days, to monitor whether any of them causes a deterioration in the skin condition. Internal treatment is prescribed only by a dermatologist. Usually these are several drugs of different groups based on the health status of each patient. External treatment is used in all cases. As a rule, external agents, such as Radevit®, are applied to the skin 2 times a day. In the morning, it is better to use medications that are easily and quickly applied to the skin; after a few minutes they should be absorbed so that you can get dressed and not worry about the smell, dirty clothes during the working day, without experiencing discomfort from the feeling of fat on the body. But in the evening and at night you don’t have to think about it. Therefore, dermatologists resort to 2-3 medications, alternating them at different times of the day, taking into account employment, profession, work schedule and the nature of the patient.

How harmful are hormonal ointments?

You always have to resort to drugs from this group during an exacerbation. Excellent anti-inflammatory and antipruritic effect immediately makes the patient’s life easier. However, even the strongest corticosteroid ointments (they are usually called hormonal) are not able to cope with inflammation for a long time if used as an independent treatment. The recommended duration of treatment with corticosteroids is no more than 2 weeks; this is usually enough to relieve the severity of the exacerbation. When the acute period has passed, treatment is continued with ointments that do not contain hormones. There are many such ointments; they are weaker than hormonal ointments, but are suitable for long-term use. Of these, it is more convenient to use emulsion-based ointments in the morning (imported emulsion-based ointments are called creams, and domestic ones can be called ointments), they are easily absorbed into the skin and usually do not smell, they contain vitamins (vitamin A contained in Radevit® ointment is especially useful for the skin ), fatty acids, methyluracil. In the evening, you can use fat-based ointments with a dissolving effect, containing sulfur, ichthyol, naphthalan, and tar. These ointments usually have an odor and are difficult to remove from the skin.

How to care for skin with eczema?

For eczema in the acute stage, it is better not to wet the affected skin. This is the basic rule for all patients. If your hands are affected, all housework should be done with gloves. Thick colored rubber gloves with a cotton coating inside (sold in hardware stores) are best suited for this; they are selected according to the size of the hand, like any other gloves, and in everyday life you need to have several pairs of them. As your gloved hands become wet, you should change them or stop doing housework. Contact with vegetables, fruits, cleaning agents, furniture care products, solvents and car cosmetics is especially harmful to hands. It is extremely undesirable to contaminate the skin with substances that are difficult to wash off. During an exacerbation, it is better to replace hand washing by cleaning them with wet wipes. If you need to use detergents, it is better to prefer odorless soap or gel, with the addition of cream or oils. In addition, so-called syndets (“soap without soap”) are now on sale - special detergents that cleanse the skin without the use of soap. The shower procedure should be short, the water should be warm (not hot!), detergents should be washed off quickly and easily, the skin, after drying with a towel (necessarily soft!) is still a little damp, immediately lubricated with cream or ointment. With eczema, the skin where there were previously rashes is usually dry, and irritation or new foci of inflammation easily occur on such skin. Due to this, she needs additional care. Creams for the body, hands, feet should always be at hand. Many cosmetic companies that produce medicinal cosmetics (sold in pharmacies) are developing special low-allergenic products for the care of dry and easily irritated skin, such as Radevit® ointment. Cosmetic creams always have a complex composition, and some of their components for eczema can cause irritation or even provoke a new exacerbation. In such cases, instead of cosmetic cream, you can use medications made on an emulsion basis, which contain vitamin A. During the treatment of eczema, it is not recommended to change cosmetics, perfumes, or washing powder, so as not to expose the skin to an unnecessary risk of developing an allergic reaction.

Can women use decorative cosmetics during treatment?

If your facial skin is affected, I think there is nothing wrong with wearing makeup. A woman’s usual appearance does not attract attention and creates inner comfort for her. Modern cosmetics (mascara, foundation, powder, eye shadow) are of high enough quality so as not to complicate the recovery period. But when you return home from work, you need to immediately remove your makeup. This is done using makeup remover milk and then an alcohol-free toner. After this, it is better to apply the remedy prescribed by the doctor. Never remove makeup with water!

Consolidation of treatment results

For any chronic skin disease, after the main course of treatment, care must be taken to ensure that the disease does not return. These are measures to improve immunity, reduce sensitivity to certain allergens, and treat common (non-skin) diseases that could contribute to the development of the disease. The best way to simultaneously solve all these problems is spa treatment. Take a vacation and go to a resort. And it doesn’t have to be a seaside resort in the summer; it’s better to time the trip to coincide with the end of treatment with a dermatologist. In recent years, it has been established that the best results for allergic diseases are obtained at local resorts, where the body is not subjected to the test of changing climatic zones. And the duration of stay there may be shorter, given that during the period of adaptation to the new climate, medical procedures are not carried out. If resort treatment is not possible, a dispensary or health center is a good choice, where you can carry out the same examination and the same procedures as at the resort. And vitamins applied in ointments and creams directly to the skin will help normalize local (in the skin) immunity.

prof. IN AND. Albanova

Indications for use

Radevit, an anti-wrinkle ointment, reviews of cosmetologists about which speak of a visible rejuvenation effect with regular use, are prescribed for a number of medical indications. They include pathological abnormalities of the skin, the course of the inflammatory process and the presence of damaged cells.

Situations when the use of the drug is necessary:

  • Ichthyosis. A hereditary disease, the main symptom of which is a violation of the formation of the stratum corneum. In case of pathology, the ointment is used as a component of complex treatment.
  • Seborrheic dermatitis. It is characterized by increased production of fat by the sebaceous glands.
  • Erosion and cracks on the surface of various natures.
  • Chemical and thermal burns ;
  • Damage caused by radiation.
  • Trophic ulcers of a non-infected nature. Their appearance is associated with insufficient tissue nutrition.
  • Allergic dermatitis during the period of weakening the inflammatory process and improving the appearance of the skin.

  • Psoriasis. It is a chronic disease. It occurs under the influence of constant stress, taking medications, endocrine pathologies and bad habits.
  • Eczema. A non-infectious disease that has a chronic form. Occurs under the influence of various factors that cause damage.
  • Atopic dermatitis. Long-term inflammation of the skin, which is recurrent in nature. Pathology develops under the influence of genetic abnormalities occurring in tissues.
  • Neurodermatitis. It manifests itself as a rash, skin lichenification and the formation of papules. The affected skin is very itchy. Radevit is effective against such itching.
  • Diffuse neurodermatitis. Associated with deviations in the innervation of the epidermis.

The drug is used for prophylactic purposes against the occurrence of various inflammatory processes and allergic manifestations on the skin. Radevit in the form of an ointment or cream is also suitable for preventing the onset of signs of aging.

Dermatologists and cosmetologists recommend Radevit to their patients to improve skin condition.

Regular use helps prolong the youth of the skin. The moisturizing and restorative properties of the product allow it to be used to solve cosmetic problems.

Contraindications

In some situations, the use of ointment is unacceptable. The drug can cause exacerbation of chronic diseases and the acquisition of new ones. The list of contraindications is small.

It is prohibited to use the product when:

  • individual intolerance to the components of the composition;
  • hypervitaminosis A, E, D;
  • in parallel, taking products containing vitamin A;
  • acute form of inflammatory skin pathologies;
  • pregnancy;
  • overdose of vitamins, which led to poisoning;
  • breastfeeding.

Radevit and atopic dermatitis

HELL

– a chronic allergic skin disease that begins in early childhood (in 90% of patients – before one year), accompanied by intense itching. It is based on genetic predisposition.

How does the disease begin?

Blood pressure begins in children at 2-3 months of age. age, usually bottle-fed, but often breast-fed (if the breastfeeding woman does not follow a diet). Initially, redness appears on the baby’s cheeks and bottom, less often on other areas of the skin - the tummy, hips, shoulders. The skin in the area of ​​redness becomes uneven, rough, and, if left untreated, becomes covered with a crust. The child becomes restless, sleeps poorly, and slightly older children experience itching. Itching intensifies with sweating and excitement. When contacting a pediatrician or dermatologist, the disease is often called food allergy, allergic dermatitis or exudative diathesis, since it is not yet chronic; if the skin lesions exist for a long time, the diagnosis is changed to AD. There is no mistake here, we are talking about different phases of the same disease.

What role does heredity play?

Hereditary factors are very important; more than 30 different genes located on different chromosomes determine a hereditary predisposition to the disease. But this is only a predisposition. For it to become a disease, additional provoking factors are needed. We call them risk factors for the development of AD. They can be divided into external and internal. Significant external factors in the first year of life primarily include food, later inhalation, bacterial, parasitic, medicinal, contact, etc. become more important. Internal factors include heredity, other allergic diseases (non-skin, for example, allergic rhinitis, conjunctivitis, bronchial asthma, pollen allergy), high skin sensitivity to irritants, nervous system diseases, dysbacteriosis.

Stress, emotional stress, unfavorable environmental conditions, and improper skin care are important factors in the occurrence of the disease.

Is AD contagious? Can a child attend kindergarten and school?

No, the disease itself is not contagious, but with intense, constant scratching, yellowish-brown crusts appear on the skin. This is a symptom of skin infection with microbes. In this case, the child becomes contagious, and microbial infection occurs through contact, that is, by touching the diseased skin. In such cases, the child should not visit the child care facility until the infection can be dealt with. The possibility of further attendance at kindergarten or school is decided by a pediatrician or dermatologist.

Can blood pressure be cured?

Yes, timely treatment almost always leads to recovery. But the hereditary predisposition to the development of the disease remains unchanged, so it is very important to avoid further provoking factors. During adolescence and adulthood, other allergic skin diseases may occur, the most common being hand eczema and allergic skin reactions to food.

What worsens the course of the disease?

First of all, non-compliance with the diet prescribed by the doctor. The diet can be prescribed by a dermatologist, pediatrician, allergist-immunologist or nutritionist. But the most important thing is for the mother of a sick child to carefully monitor the skin’s reaction to certain foods and exclude them from the diet. Daily keeping of a food diary, even the most primitive one, which is a record of a list of food eaten during the day with notes on accidentally consumed foods (donated candy, ice cream, nuts, etc.) and the condition of the skin on the same day, allows you to quickly identify what should be excluded. Any infectious diseases, emotional overload, bad weather, smoking in the family, and dust in the apartment also worsen the condition of the skin. With age, seasonal fluctuations in the course of the disease develop, with improvement in summer and worsening in early spring and late autumn.

How to treat blood pressure?

Treatment must be taken seriously. External remedies alone are never sufficient for recovery or long-term improvement. It is also necessary to use internal treatment to ensure a long-term effect. Oral medications are prescribed by a dermatologist or an immunologist-allergist, so we will not dwell on this here, we will only note that without medical help, “home remedies” alone cannot cure the disease.

Now about external means. In recent years, corticosteroid ointments have taken the leading place among them; they are commonly called hormonal. From the many (more than 50) drugs in this series, dermatologists choose an ointment for each child in accordance with the optimal balance of benefit, safety and price. Without denying the undoubted benefits of corticosteroid ointments during periods of exacerbation of blood pressure, we note that none of them is suitable for long-term use, and the disease can be active for many months. In addition, no drug has been developed specifically for the treatment of children. In this regard, each specialist, trying to minimize the drug load on the child’s body by reducing the concentration of the drug applied to the skin, usually suggests mixing hormonal ointment with various creams, oils, solutions or other ointments. Mixing is extremely undesirable, since this may change the effect of both components of the mixture. It is much better to first use a hormonal ointment for a short time (5-7 days), and then change it to one that does not contain hormones. There are such means and there are many of them.

There are other situations in which it is necessary to decide on replacing hormonal ointments, for example: a child has been treated with corticosteroid ointments for a long time, addiction has set in - what to treat next? Or - there is no more inflammation and itching, but the skin remains dry and easily irritated - how to eliminate these phenomena?

In such cases, ointments containing vitamin A, naftalan oil, tar, methyluracil, etc. are used. Dermatologists know these products and can always help in choosing a drug depending on the problems being solved.

What place do children's cosmetics play in treatment?

Baby creams, powders, foams, soaps, shampoos are cosmetic, that is, they do not have auxiliary care products or medicinal value. It is impossible to replace the treatment of blood pressure with the use of such drugs, no matter what miraculous effect is declared by advertising and the inscription on the packaging. At the same time, accompanying treatment with care products cannot be underestimated. For example, when washing a child, it is better to use soaps, gels and foams specially designed for children. Creams can be used to soften the skin during a favorable period when there are no manifestations of the disease.

What medications can be used in the interval between exacerbations?

In order to prevent the onset of another exacerbation, it is better to use medicinal ointments with vitamins; vitamins A, D and E are especially useful and necessary for the skin. In addition, it is very important during this period to take care of improving immunity, treating internal diseases, and strengthening the body.

Is it possible to travel to the South, Turkey and Egypt with a sick child?

It is always useful to relax in the South by the sea. It should be remembered that when the climate zone changes, the child’s adaptation period takes about 10 days. This is a dangerous period - you can get a cold, your skin condition may worsen, herpes, infections, poor health, lethargy, and fever are common. The younger the child is, the more difficult adaptation is. Complete rest and health benefits come only after this period. In this regard, my recommendation is that a vacation in the South should be long, taking a child to the sea for 1-2 weeks is dangerous - this is a difficult test for the body, because when returning to its usual habitat, the adaptation process begins again, and its duration is the same . And a few more words about the trip to the South. Exposure to the sun is very dangerous - sunburn can occur despite the application of sunscreen. Keep children in the shade, especially between 10 a.m. and 4 p.m., and at other times use creams with an SPF of at least 40. Remember that most of these creams should be reapplied after swimming. And if sunburn does occur, medicinal ointments with vitamin A will help you. You can buy them at the pharmacy without a prescription, but you need to do this in advance - they are not sold abroad.

prof. IN AND. Albanova

Instructions for use, dosage of the drug

The ointment has a wide range of action. Before starting use, it is important to decide what result is expected from the course of therapy. This feature is very important, because the approach to drawing up a treatment program depends on it.

You shouldn’t expect Radevit to get rid of deep wrinkles that have already appeared on your face. The drug is much more effective when carrying out preventive measures. The use of ointment according to a scheme developed individually by a cosmetologist helps to avoid the appearance of wrinkles on the face.

For face

Signs of skin aging appear against the background of a deficiency of vitamins in the body and the negative influence of the environment. The rich composition of Radevit saturates the skin with essential substances, preventing aging. The skin must first be cleaned of dust, sebaceous secretions and other contaminants.

After cleansing, the effect of Radevit will be maximum. It is recommended to use a moisturizing gel for washing. Wounds and cracks are carefully treated with an antiseptic composition. Then wipe the surface with tonic, lotion and move on to cream. It is recommended to steam the surface to make it easier for the components to penetrate the layers of the epidermis.

To preserve youthful skin, the ointment is applied to the face once a day. It is advisable to carry out the procedure in the evening.

Radevit is distributed in a thin layer, lightly massaging. This will help the beneficial substances quickly absorb into the layers and penetrate as deeply as possible. For therapeutic purposes, apply the product to the affected areas of the skin 2 times a day. The method of use remains the same as for prophylactic use.

It is important to consider that the product does not contain an SPF filter, so in the summer the risk of pigmentation increases. The ointment also works well against acne and pimples. It has a powerful anti-inflammatory effect.

For maximum effect, it is recommended to use moisturizing masks in parallel with the cream. They are applied at a time when the drug has already been completely absorbed into the skin. After a month's course of use, the skin is noticeably moisturized and its metabolic process improves. By retaining moisture in the intercellular space, wrinkles will become less noticeable.

Radevit activates regenerative processes in the skin, which leads to skin renewal. For acne, the drug is used 2 times a day for 3-5 days. Already on the 2nd day of use, redness and itching disappear.

Around eyes

It will not be possible to remove expression lines or age-related wrinkles in the eye area using Radevit. The cream contains retinol. This substance causes severe irritation on the delicate skin of the eyelids. In addition, the use of the product in this area can result in swelling, redness of the skin and tearing.

The effectiveness of Radevit® ointment containing retinol palmitate, ergocalciferol and tocopherol acetate on an emulsion basis was studied in 53 patients with skin diseases. The ointment was applied openly, under gauze or occlusive dressing. It has been established that the ointment has a pronounced softening, moisturizing, reparative effect, reduces skin inflammation, normalizes keratinization processes, restores skin elasticity, its turgor, reduces itching and pain. The ointment is highly effective for skin diseases and conditions accompanied by severe dryness, peeling, formation of cracks, erosions, abrasions, and allergic diseases. The ointment can be recommended to prevent premature skin aging. You should refrain from using it at the height of inflammatory reactions. The ointment is well tolerated and easy to use.

The purpose of the clinical study of the drug

was to clarify the indications for the use of Radevit® ointment in dermatological practice. We observed 53 patients who received inpatient or outpatient treatment at the clinic of skin and venereal diseases of the MMA named after. THEM. Sechenov. Among them are 26 men and 27 women, aged from 14 to 67 years.

The ointment was applied 2 times a day in a thin layer without rubbing for 3 weeks. When applying the ointment to the limbs, gauze bandages were used. In case of abundant layering of scales, occlusive dressings were used. Before starting therapy, all patients underwent a clinical and laboratory examination, which included a general and biochemical blood test, and a urine test.

During the study of the effectiveness of the drug, symptoms such as hyperemia, edema, weeping, infiltration, lichenification, papules, dry skin, peeling, cracks, itching, burning, and soreness were assessed. The dynamics of symptoms were assessed in points before treatment, and then after each week of observation on a 4-point scale: 1 - no symptom, 2 - mildly expressed, 3 - moderately expressed, 4 - severely expressed. The obtained results were subjected to statistical processing using the parametric Student test (t). Differences in symptoms compared with baseline signs were considered significant at P

Three groups of patients were observed:

  1. with disturbances in the keratinization process and age-related changes in the skin;
  2. with dermatitis and allergic dermatoses;
  3. with other diseases.

Disorders of the keratinization process, age-related skin changes

This group included patients with psoriasis - 12 people; patients with easily vulnerable skin exposed to damaging factors, age-related changes, xeroderma - 7 people and 1 patient with ordinary ichthyosis.

Among patients with psoriasis (8 men and 4 women aged 25 to 66 years), ordinary psoriasis was observed in 8 patients, exudative psoriasis in 2, and 2 patients suffered from palmoplantar psoriasis. Duration of the disease from 1 year to 18 years. All patients had a stationary stage of the process. The patients received traditional therapy with sedatives, desensitizing agents, injections of B vitamins, and physiotherapeutic procedures (Ultraviral irradiation, paraffin baths).

As can be seen from table.
1, when using Radevit® ointment during the first week, a significant flattening of the papules is observed. By the end of the second week, the brightness of the rashes, dry skin and peeling significantly decreased in the group as a whole. Plaque infiltration decreased noticeably only by the end of the 3rd week of drug use. When “Radevit” was prescribed under an occlusive dressing for palmoplantar psoriasis, accompanied by pronounced, sharply painful cracks, by the end of the second week, complete epithelization of the cracks, absence of pain, and a slight decrease in hyperemia were noted. However, infiltration in the foci did not change significantly. The best therapeutic effect was observed when treating lesions on the scalp with ointment (occlusive dressings for 1-1.5 hours). Clinical cure was achieved by 16-17 days of therapy. Table No. 1.
Dynamics of clinical symptoms in patients with psoriasis during local treatment with Radevit® ointment in points (M ± m).

SymptomsBefore treatmentFirst weekSecond weekThird week
Erythema3,0 ± 0,242,43 ± 0,222,0 ± 0,0*1,71 ± 0,20
Papules3,3 ± 0,162,60 ± 0,23*2,30 ± 0,272,10 ± 0,33
Infiltration3,0 ± 0,202,63 ± 0,202,50 ± 0,202,13 ± 0,32*
Dryness3,25 ± 0,312,63 ± 0,402,0 ± 0,33*1,38 ± 0,22
Peeling3,5 ± 0,292,63 ± 0,281,75 ± 0,27*1,50 ± 0,20

In two patients, when using the drug for one week, negative dynamics were noted. Thus, patient M., 48 years old, with diffuse exudative lesions of the scalp, noted an increase in the phenomena of exudation in the form of increased formation of large-plate scales-crusts soaked in serous fluid. The second patient, who used Radevit® on the palms and soles, noted increased itching, hyperemia and pain in the cracks.

Dermatitis and allergic dermatoses

In this group, 19 patients with atopic dermatitis, 8 patients suffering from eczema, and 1 patient with bullous photodermatitis received treatment with Radevit® ointment.

Among the patients with atopic dermatitis there were 8 women and 11 men aged from 14 to 38 years. Clinical diagnosis was established based on the diagnostic criteria proposed by Hanifin and Rajka (1980). The group included patients with both localized skin lesions (hyperemia, lichenification in the elbow and popliteal folds, on the skin of the face and neck), and with widespread small-papular rashes with a tendency to erythroderma. Patients were bothered by a sharp, sometimes painful itching, and a feeling of tightness of the skin. At the clinic, patients received traditional therapy, including antihistamines, desensitizing and psychotropic drugs, vitamins C and B, physiotherapeutic procedures (UV irradiation, D'Arsonval currents, IHF therapy, paraffin baths, etc.), topical indifferent creams and ointments.

Table 2 shows that such characteristics as erythema, papules, infiltration, dry skin, peeling and itching significantly change within a week after the start of smearing the lesions with “Radevit”.
Signs of lichenification significantly decreased by the end of the second week. In this case, almost complete epithelization of the cracks is observed. However, moderate lichenification in the lesions persists even after three weeks of use of the ointment. All patients noted a decrease in the feeling of skin tightness and indicated an increase in its elasticity in the affected areas. From our point of view, the drug should not be prescribed when the severity of the process is pronounced, and especially on the skin of the face. Thus, under our observation was patient M., 17 years old, with facial skin lesions in the form of bright hyperemia, swelling, moderate infiltration, abundant exfoliation and hemorrhagic crusts. When using “Radevit” for a week, the feeling of skin tightness decreased somewhat, but all other symptoms remained, and the hyperemia increased somewhat. Table No. 2.
Dynamics of clinical symptoms in patients with atopic dermatitis during local treatment with Radevit® ointment in points (M ± m).

SymptomsBefore treatmentFirst weekSecond weekThird week
Erythema2,94 ± 0,172,11 ± 0,17*1,65 ± 0,121,35 ± 0,12
Infiltration3,0 ± 0,202,24 ± 0,19*1,71 ± 0,181,59 ± 0,17
Lichenification3,0 ± 0,222,94 ± 0,221,94 ± 0,17*1,82 ± 0,16
Papules2,77 ± 0,232,06 ± 0,23*1,53 ± 0,181,29 ± 0,19
Dryness3,35 ± 0,182,41 ± 0,20*1,88 ± 0,121,53 ± 0,13
Peeling2,82 ± 0,162,06 ± 0,14*1,65 ± 0,121,12 ± 0,11
Cracks2,0 ± 0,311,35 ± 0,121,1 ± 0,12*1,0 ± 0,0
Itching3,06 ± 0,322,12 ± 0,18*1,65 ± 0,191,29 ± 0,12

We observed 4 women and 4 men aged from 20 to 56 years with different types of eczema, in the subacute and chronic stages.
The process was localized more often on the hands and feet and was represented by pronounced skin infiltration, hyperemia, with a stagnant tint, abundant small-papular rashes, deep painful cracks, layers of fine-lamellar scales, and areas of hyperkeratosis on the palms and soles. Patients complained of a feeling of skin tightness and moderate itching. At the same time, traditional therapy was carried out with antihistamines and sedatives, B vitamins, diuretics and laxatives, local baths with sea salt, lotions, indifferent creams and pastes. Table No. 3.
Dynamics of clinical symptoms in patients with eczema during local treatment with Radevit® ointment in points (M ± m).

SymptomsBefore treatmentFirst weekSecond weekThird week
Erythema2,44 ± 0,262,11 ± 0,211,44 ± 0,19*1,33 ± 0,18
Infiltration3,33 ± 0,312,66 ± 0,312,11 ± 0,20*1,88 ± 0,33
Papules2,22 ± 0,331,88 ± 0,311,66 ± 0,321,44 ± 0,23*
Dryness3,44 ± 0,362,44 ± 0,26*1,77 ± 0,161,44 ± 0,19
Peeling3,44 ± 0,362,44 ± 0,311,44 ± 0,26*1,33 ± 0,18
Cracks2,66 ± 0,392,0 ± 0,251,1 ± 0,12*1,0 ± 0,0
Itching2,22 ± 0,231,66 ± 0,251,66 ± 0,231,33 ± 0,18*

When analyzing the results of local therapy of patients with eczema with Radevit® ointment for the whole group, it was found that during the first week only dry skin significantly decreased, by the end of the second week there was a significant weakening in the brightness of the color of the lesions, a decrease in infiltration and peeling, and epithelization of cracks. Papules and itching underwent noticeable regression only at the end of the drug trial, that is, at the end of the third week. Patient P., 56 years old, had mild weeping, which resolved by the 12-13th day of using the ointment.

It seems inappropriate to prescribe the drug in the acute stage of the process. Thus, we noted negative dynamics in a 44-year-old patient who was admitted with a sharp exacerbation of eczema of the hands. Radevit® was prescribed immediately after the swelling decreased and the appearance of fresh blisters stopped. On the third day of use, the appearance of abundant, small, bright pink, conical papules was again noted on the back of the hands. Thus, in such cases, the use of ointment should be considered premature.

The result of prescribing Radevit® ointment for bullous photodermatitis that developed after an overdose of ultraviolet radiation in a patient with psoriasis is interesting. On the third day of using the ointment, swelling and pain completely disappeared; by days 8-10, hyperemia significantly decreased, and active epithelization of erosions was noted. By 19-20 days, complete regression of the rash was achieved.

Other diseases

This group included 5 patients. A positive effect was noted in the treatment of a 33-year-old patient with ulcerative pyoderma of the leg. The duration of the disease was one month. Radevit® ointment was applied under a bandage twice a day after cleaning ulcers and lotions with furacillin solution. Within a week, the hyperemia around the ulcers was completely resolved, the pain syndrome disappeared, and by the end of the second week, complete scarring was recorded.

The ointment also had a beneficial effect on widespread lichen sclerosus in a 65-year-old woman. After using “Radevit,” the elasticity of the lesions noticeably improved, and unpleasant subjective sensations disappeared.

When trying to use the ointment in two patients with alopecia areata and one with lichen planus, no clear dynamics were observed for 3 weeks.

Conclusion

During testing it was established that Radevit® ointment:

  • has a pronounced softening, moisturizing, reparative effect;
  • reduces skin inflammation;
  • normalizes keratinization processes;
  • restores skin elasticity and turgor;
  • reduces itching and pain.

It should be noted that the drug is highly effective in the complex treatment of skin diseases and conditions accompanied by severe dryness, peeling, the formation of cracks, erosions, abrasions (ichthyosis, eczema, age-related skin changes), inflammatory, including allergic, diseases (eczema, atopic dermatitis, dermatitis, psoriasis). The ointment should be recommended for the prevention of premature skin aging.

From our point of view, one should refrain from using the ointment at the height of acute inflammatory reactions, and prescribe it in the subacute and chronic stages of the process, during the period of predominance of dryness and peeling.

It should be noted that Radevit® ointment is well tolerated. Laboratory monitoring during treatment did not reveal any deviations in clinical and biochemical blood tests or urine tests.

O.L. Ivanov, M.A. Samgin, O.V. Grabovskaya

Seal

Side effects

If the rules for using the drug are not followed, unpleasant symptoms may occur.

Radevit, an anti-wrinkle ointment, reviews of cosmetologists about which help to assess the likelihood of complications occurring after taking it, causes adverse reactions in the body:

  • Hypervitaminosis. Occurs with prolonged treatment of large areas of skin and parallel intake of vitamins included in the ointment.
  • Allergic manifestations. Occurs with repeated use of the ointment. In some cases, a negative reaction from the body may occur immediately. A side effect occurs in the form of urticaria. The drug does not cause angioedema and anaphylactic shock. Symptoms disappear after taking antihistamine drops or tablets.

  • Swelling and itching. Most often occurs when using the drug over manifestations of inflammatory skin diseases. Radevit promotes the accumulation of moisture in the lesion, which aggravates the course of the disease.
  • Impact on the child during pregnancy and breastfeeding. The consequences of use have not been fully studied. At the same time, the likelihood of pregnancy complications and congenital defects in the newborn remains. When breastfeeding, a child may have an allergic reaction to the components included in the composition.

The use of ointment can lead to skin irritation, hyperemic reactions and soreness of the skin.

Rules for using Radevit cream

The effect of using the ointment will be visible with systematic use. It is recommended to apply the drug in a thin layer to the skin twice a day:

  • You can apply the ointment to your lips. The cracks will heal, and the protective layer of Radevit will not allow your lips to become chapped. Blot your lips with a paper towel to remove excess;
  • For any type of burn, apply the ointment twice a day to the affected areas and once before bedtime. Regeneration occurs faster at night;
  • If you use Radevit as an anti-wrinkle drug, apply it in the morning and before bed. It is not recommended to apply the cream to the eyelids; smudges and tearing may occur. The result improves if you have previously completed a course of peelings with fruit acids;
  • If you have deep wounds, cracks, or very flaky skin, then buy special bandages at the pharmacy that will help the skin recover. We recommend treating wounds with an antiseptic in advance;
  • In the case of pimples, blackheads, and reddish stains, apply the ointment to a cotton swab and apply it pointwise to the damaged area of ​​the skin. Radevit helps the formation of a new layer of skin, so we recommend using it for teenagers who have abundant secretion of the sebaceous glands.

special instructions

To achieve maximum results when applying ointment, it is important to follow a number of rules.

Among the special instructions for the use of Radevit:

  • The simultaneous use of ointment and other drugs containing vitamins D, E, A and retinoids is prohibited. This will protect the body from the development of hypervitaminosis.
  • The use of hormonal therapy reduces the effectiveness of Radevit application.
  • If side effects occur, you can neutralize the effect of the cream using glucocorticosteroids or salicylates.
  • To prevent the occurrence of hypervitaminosis, it is recommended to apply the cream to small areas of the skin.
  • In case of severe exfoliation of the stratum corneum, the instructions for use recommend applying special dressings over the ointment. They protect the damaged area of ​​the skin from oxygen penetration.
  • Cracks, wounds and other damage must be pre-treated with an antiseptic.

Radevit is suitable for long-term use. The maximum duration of treatment can be 3 months.

Indications and contraindications

Radevit is considered a medicinal cosmetic product, therefore the packaging includes instructions for use.

Indications for use of Radevit cream:

  • dermatitis, dermatoses;
  • chapping of the skin and increased dryness;
  • diffuse keratoma;
  • eczema and psoriasis;
  • seborrhea;
  • diffuse neurodermatitis;
  • cracks;
  • uninfected wounds;
  • erosions and ulcers;
  • burns;
  • prevention of inflammation and allergic reactions after treatment with topical corticosteroids.

Contraindications:

  • hypervitaminosis of one of the vitamins;
  • individual intolerance to individual components;
  • taking retinoids;
  • exacerbation of skin inflammation.

Pregnant women are advised to consult a dermatologist before use. Each case is unique and requires a specialist opinion.

Radevit cream should be applied with extreme caution in the summer. It is advisable to remain indoors for at least two hours after use. The properties of the cream attract ultraviolet rays, and pigment spots may appear on the skin.

Analogs

Radevit, an anti-wrinkle ointment, reviews of which from cosmetologists are in most cases good, has a unique structure. There are no drugs that are the same. Analogues are only similar in their effect.

Among analogues:

  • Linin. The components of the composition are similar to Radevit. Suitable for treating wounds and various surface damage. Accelerates the restoration of tissue integrity and relieves severe itching. The cost for 30 g of the drug starts from 60 rubles.
  • Linetol. Metabolic ointment, the action of which is aimed at normalizing the metabolic processes that occur in the layers of the dermis. Available in solution form. For one 100 ml bottle you will have to pay approximately 138 rubles.
  • Colocyl. The product has an antiseptic and restorative effect. Sold in the form of a sponge, the cost of which varies from 90 to 150 rubles. Apply to damaged skin.
  • Carl. The drug has a wound healing and reparative effect. The sponge is soaked in ointment. Suitable for people who suffer from frequent allergies. It does not cause negative reactions in the body. It is used for radiation diseases of the mucous membranes and skin.

Each drug has its own composition, contraindications and side effects. Therefore, it is not recommended to change the drug yourself to a similar medicine. Before doing this, you should consult with your doctor. He will advise which ointment is best as a replacement.

Compound

Radevit face cream has restorative properties thanks to a selected composition with useful, natural ingredients. The ointment is rich in vitamins A, E, D, which contribute to skin health:

  • A - has an anti-inflammatory and restorative effect. 10 mg of vitamin helps the skin renew itself and the photoaging process slows down. The cream compensates for the lack of this vitamin in people over 35 years of age, in whom it begins to be produced in smaller quantities.
  • E is a natural antioxidant. It is this vitamin that prevents aging and protects the skin from external factors. The skin remains moisturized for a long time, as the vitamin accumulates in it and binds water molecules. It contains 5 mg.
  • D - protects the natural immunity of the epithelium. The vitamin does not allow harmful bacteria to pass through, eliminates inflammation, and prevents dry skin. The ointment contains 50 mg.

In addition to vitamins, Radevit cream includes components to thicken the consistency: glycerin, petroleum jelly, alcohol, butylated hydroxyanisole, ethanol 95%, butylated hydroxytoluene, water.

Price in pharmacies in Moscow, St. Petersburg, regions

The cost of a medicine depends on many parameters. It can be influenced by the pharmacy chain and its location, the pharmaceutical company and the country of manufacture. Radevit is considered an affordable drug, its price is relatively low. You can purchase the ointment both in city pharmacies and through the online store.

The approximate cost in different cities is presented in the table.

CityPrice for 35 g, rub.
Moscowfrom 336
Saint Petersburgfrom 329
Ekaterinburgfrom 313
Ryazanfrom 329
Vladivostokfrom 345

What cosmetologists say about the effectiveness of Radevit ointment

Cosmetologists leave positive reviews about the drug. They note that Radevit in the form of an anti-wrinkle ointment is highly effective.

Its composition is natural. It contains useful substances and is free of aromatic fragrances and dyes. The drug gives good results not only in the fight against wrinkles, but also in flaking and dry skin.

Experts urge you to come for a consultation before using the ointment. Despite the fact that Radevit is one of the effective cosmetic products, its use can be harmful. Still, this is not a simple care cream, but a medicinal ointment. Its purpose requires an individual approach.

Cosmetologists say that you should take its use during menopause and menopause seriously. If the sweat glands are too active, you will have to abandon the product altogether. Compared to anti-aging cosmetics, the consistency of the cream is not as thick and greasy.

Despite this, the product moisturizes and nourishes the skin well. Radevit should be used with caution. It can clog pores. Patients sometimes complain of a feeling of discomfort and a constant feeling of a creamy texture on the skin. Radevit has a wide spectrum of action.

Reviews from cosmetologists say that the ointment can be used to prevent the appearance of wrinkles on the face, moisturize hands and lips. It is also used for complex treatment of dermatological diseases. To get maximum results from application, it is important to follow specific instructions and become familiar with contraindications and side effects.

What is important to know about the effectiveness of the product

Radevit cream and ointments are the development of a Russian pharmaceutical company and at the moment it is one of the most well-proven medicines. Among the numerous drugs for the treatment of skin diseases, it is the ointments and creams of the Radevit brand that are praised for their high effectiveness, balanced composition, which is allowed to be used even by young children, pregnant women (with the consent of the attending physician), and used both for the skin of the hands and faces. It helps fight age-related changes, treats peeling, and saves you from chicks in winter, being an effective means of preventing frostbite.

Curious! Radevit has another huge advantage. This is the price. The product is quite inexpensive (about 300 rubles per tube), but is used very sparingly - a small pea is enough to completely lubricate the face or hands and achieve speedy healing.

The cream is considered a dermoprotector, that is, a way to protect the epithelium from external factors. It does not contain hormones, although the therapeutic effect is superior to many strong drugs. But the main secret is in the unique composition, where the most beneficial components for the skin are selected. Let's tell you what "Radevit" consists of.

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